SPRO vs SY

Comparison between Spero Therapeutics Inc (SPRO, Company) and So-Young International Inc (SY, Company).

Both SPRO and SY are from the Healthcare sector.

5-Year PerformanceSY has outperformed SPRO, delivering a return of -25.1% compared to -28.6%

SPRO vs SY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SPRO(COMPANY)	SY(COMPANY)
Market Cap	$147M	$146M
Max Drawdown	97.46%	97.54%
Sharpe Ratio	0.09	1.21
5Y Beta	0.60	0.84
Industry	Biotechnology	Health Information Services
P/E Ratio	9.31	-4.23
Forward P/E	N/A	16.29
PEG Ratio	0.00	N/A
Dividend Yield	N/A	5.26%
5Y Dividends CAGR	30.26%	N/A
Debt to Equity	0.00%	2.56%
Free Cash Flow Yield	4.93%	-10.29%
P/S Ratio	2.42	0.11
P/B Ratio	2.81	0.86

Market Cap

Winner

SPRO

$147M

$146M

Max Drawdown

Winner

SPRO

97.46%

97.54%

Sharpe Ratio

SPRO

0.09

Winner

1.21

5Y Beta

Winner

SPRO

0.60

0.84

Industry

SPRO

Biotechnology

Health Information Services

P/E Ratio

SPRO

9.31

Winner

-4.23

Forward P/E

SPRO

N/A

16.29

PEG Ratio

SPRO

0.00

N/A

Dividend Yield

SPRO

N/A

5.26%

5Y Dividends CAGR

SPRO

30.26%

N/A

Debt to Equity

Winner

SPRO

0.00%

2.56%

Free Cash Flow Yield

Winner

SPRO

4.93%

-10.29%

P/S Ratio

SPRO

2.42

Winner

0.11

P/B Ratio

SPRO

2.81

Winner

0.86

SPRO vs SY - Historical Returns

Returns include dividend reinvestment.

Period	SPRO	SY
1 month	+12.20%	-36.95%
3 months	+10.04%	-40.19%
6 months	+22.84%	-39.81%
1 year	-1.38%	+98.10%
5 years(CAGR)	-28.65%	-25.06%
10 years(CAGR)	-2.10%	N/A
Max(CAGR)	-0.31%	-25.83%

Winner

SPRO

+12.20%

-36.95%

Winner

SPRO

+10.04%

-40.19%

Winner

SPRO

+22.84%

-39.81%

SPRO

-1.38%

Winner

+98.10%

5Y(CAGR)

SPRO

-28.65%

Winner

-25.06%

10Y(CAGR)

SPRO

-2.10%

N/A

Max(CAGR)

Winner

SPRO

-0.31%

-25.83%

SPRO vs SY - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	SPRO	SY
2026	+21.28%	-30.34%
2025	+115.74%	+232.45%
2024	-32.24%	-27.16%
2023	-15.52%	-11.03%
2022	-88.58%	-60.67%
2021	-10.71%	-70.24%
2020	+96.45%	-8.41%
2019	+53.59%	-32.86%
2018	-49.34%	N/A
2017	+2.17%	N/A
2015	+125.03%	N/A
2014	-36.85%	N/A
2013	+87.73%	N/A
2012	-15.94%	N/A
2011	-18.88%	N/A
2010	-29.17%	N/A
2009	+37.55%	N/A
2008	-59.66%	N/A
2007	+44.06%	N/A
2006	+26.56%	N/A
2005	-15.34%	N/A
2004	+7.04%	N/A

SPRO vs SY Drawdown Comparison

The maximum drawdown for SPRO was -97.46%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for SY was -97.54%, occurring on Oct 31, 2022. This drawdown has not yet recovered.

The current SPRO drawdown is -87.09%. The current SY drawdown is -89.53%.

Rank	SPRO	SY
#1	-97.46% Dec 28, 2020 - Apr 8, 2025	-97.54% May 3, 2019 - Oct 31, 2022
#2	-85.13% Jul 17, 2007 - Nov 2, 2017	N/A
#3	-70.48% Apr 12, 2018 - Dec 8, 2020	N/A
#4	-42.56% May 17, 2005 - Feb 16, 2007	N/A
#5	-32.47% Nov 13, 2017 - Apr 9, 2018	N/A
#6	-18.79% Mar 12, 2007 - Jun 19, 2007	N/A
#7	-9.16% Jun 25, 2007 - Jul 3, 2007	N/A
#8	-8.75% Dec 3, 2004 - Mar 28, 2005	N/A
#9	-5.73% Feb 21, 2007 - Mar 7, 2007	N/A
#10	-5.34% Dec 8, 2020 - Dec 16, 2020	N/A
#11	-4.94% Mar 28, 2005 - May 11, 2005	N/A
#12	-4.48% Dec 17, 2020 - Dec 21, 2020	N/A
#13	-4.01% Jul 9, 2007 - Jul 13, 2007	N/A
#14	-2.82% Nov 22, 2004 - Nov 24, 2004	N/A
#15	-2.50% Nov 24, 2004 - Dec 1, 2004	N/A