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XBI vs IXN

Comparison between STATE STREET(R) SPDR(R) S&P(R) BIOTECH ETF (XBI, ETF) and ISHARES GLOBAL TECH ETF (IXN, ETF).

XBI is from the Healthcare sector, while IXN is from the Technology sector.

5-Year PerformanceIXN has outperformed XBI, delivering a return of +19.9% compared to +4.5%

XBI vs IXN - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Net Assets
Winner
XBI
$9.60B
IXN
$9.50B
Expense Ratio
Winner
XBI
0.35%
IXN
0.39%
Max Drawdown
XBI
63.90%
Winner
IXN
56.25%
Sharpe Ratio
Winner
XBI
2.24
IXN
1.42
5Y Beta
Winner
XBI
0.97
IXN
1.46
P/E Ratio
Winner
XBI
-9.20
IXN
32.31
Forward P/E
XBI
N/A
IXN
19.48
PEG Ratio
XBI
N/A
IXN
0.21
5Y Dividends CAGR
XBI
12.45%
Winner
IXN
19.43%
5Y EPS CAGR
XBI
6.71%
Winner
IXN
35.85%
Debt to Equity
Winner
XBI
36.66%
IXN
55.54%
P/S Ratio
XBI
9.00
Winner
IXN
5.96
P/B Ratio
Winner
XBI
4.96
IXN
7.77

XBI vs IXN - Holdings Comparison

XBI and IXN have 1 common holdings. Overlap is -0.08%

XBI's top 25 holdings weight is 31.60%. IXN's top 25 holdings weight is 77.95%.

RankXBIIXN
#1
APOGEE THERAPEUTICS INC (APGE) - 1.61%
NVIDIA CORP (NVDA) - 13.09%
#2
ORUKA THERAPEUTICS INC (ORKA) - 1.42%
APPLE INC (AAPL) - 12.70%
#3
KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 1.41%
MICROSOFT CORP (MSFT) - 7.94%
#4
ERASCA INC (ERAS) - 1.39%
n/a (n/a) - 5.12%
#5
DIANTHUS THERAPEUTICS INC (DNTH) - 1.31%
BROADCOM INC (AVGO) - 4.89%
#6
VIKING THERAPEUTICS INC (VKTX) - 1.30%
MICRON TECHNOLOGY INC (MU) - 4.08%
#7
SPYRE THERAPEUTICS INC (SYRE) - 1.28%
SAMSUNG ELECTRONICS CO LTD (n/a) - 3.75%
#8
TWIST BIOSCIENCE CORP (TWST) - 1.28%
ADVANCED MICRO DEVICES INC (AMD) - 3.31%
#9
MODERNA INC (MRNA) - 1.28%
SK HYNIX INC (n/a) - 3.01%
#10
CG ONCOLOGY INC (CGON) - 1.27%
ASML HOLDING NV (n/a) - 2.65%
#11
PROTAGONIST THERAPEUTICS INC (PTGX) - 1.26%
INTEL CORP (INTC) - 2.12%
#12
n/a (PRAX) - 1.25%
APPLIED MATERIALS INC (AMAT) - 1.73%
#13
REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.24%
CISCO SYSTEMS INC (CSCO) - 1.66%
#14
MIRUM PHARMACEUTICALS INC (MIRM) - 1.23%
LAM RESEARCH CORP (LRCX) - 1.61%
#15
RHYTHM PHARMACEUTICALS INC (RYTM) - 1.21%
n/a (PLTR) - 1.12%
#16
COGENT BIOSCIENCES INC (COGT) - 1.21%
KLA CORP (KLAC) - 1.12%
#17
VAXCYTE INC ORDINARY SHARES (PCVX) - 1.21%
PALO ALTO NETWORKS INC (PANW) - 1.07%
#18
RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 1.20%
INTERNATIONAL BUSINESS MACHINES CORP (IBM) - 1.04%
#19
NATERA INC (NTRA) - 1.20%
TEXAS INSTRUMENTS INC (TXN) - 1.02%
#20
ROIVANT SCIENCES LTD ORDINARY SHARES (ROIV) - 1.19%
SANDISK CORP ORDINARY SHARES (SNDK) - 0.95%
#21
BRIDGEBIO PHARMA INC (BBIO) - 1.19%
ORACLE CORP (ORCL) - 0.90%
#22
ALKERMES PLC (ALKS) - 1.17%
MARVELL TECHNOLOGY INC (MRVL) - 0.80%
#23
TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 1.17%
TOKYO ELECTRON LTD (n/a) - 0.77%
#24
CYTOKINETICS INC (CYTK) - 1.17%
MEDIATEK INC (n/a) - 0.75%
#25
INSMED INC (INSM) - 1.15%
CROWDSTRIKE HOLDINGS INC CLASS A (CRWD) - 0.75%
Total Holdings156147

XBI vs IXN - Historical Returns

Returns include dividend reinvestment.

1M
XBI
-3.97%
Winner
IXN
+3.69%
3M
Winner
XBI
+17.85%
IXN
+9.98%
6M
XBI
+25.50%
Winner
IXN
+32.61%
1Y
Winner
XBI
+85.27%
IXN
+47.36%
5Y(CAGR)
XBI
+4.46%
Winner
IXN
+19.88%
10Y(CAGR)
XBI
+9.75%
Winner
IXN
+23.96%
Max(CAGR)
XBI
+11.96%
Winner
IXN
+12.48%

XBI vs IXN - Annual Returns (2001 - 2026)

Returns include dividend reinvestment.

YearXBIIXN
2026+29.62%+33.17%
2025+33.70%+25.60%
2024-0.05%+28.36%
2023+9.54%+54.20%
2022-28.10%-30.60%
2021-20.55%+30.90%
2020+49.01%+41.15%
2019+30.54%+47.55%
2018-17.55%-6.75%
2017+42.81%+40.11%
2016-12.49%+15.95%
2015+12.40%+4.27%
2014+44.27%+16.69%
2013+42.97%+21.45%
2012+32.95%+13.68%
2011+3.91%-4.54%
2010+15.74%+8.27%
2009-0.82%+48.03%
2008-8.58%-42.01%
2007+30.24%+12.40%
2006-6.48%+6.99%
2005N/A+5.43%
2004N/A+2.41%
2003N/A+41.04%
2002N/A-38.26%
2001N/A+0.32%

XBI vs IXN Drawdown Comparison

The maximum drawdown for XBI was -63.89%, occurring on May 11, 2022. This drawdown has not yet recovered.

The maximum drawdown for IXN was -55.66%, occurring on Mar 9, 2009. Recovery took 1099 trading sessions.

The current XBI drawdown is -8.97%. The current IXN drawdown is -5.82%.

RankXBIIXN
#1-63.89%
Feb 8, 2021 - May 11, 2022		-55.66%
Oct 31, 2007 - Mar 13, 2012
#2-49.25%
Jul 17, 2015 - Jan 12, 2018		-55.51%
Dec 6, 2001 - Jan 4, 2007
#3-37.67%
Aug 14, 2008 - Apr 14, 2011		-36.30%
Dec 27, 2021 - Nov 20, 2023
#4-35.26%
Jun 20, 2018 - May 11, 2020		-30.89%
Feb 19, 2020 - Jun 10, 2020
#5-29.06%
Feb 27, 2014 - Oct 28, 2014		-25.55%
Feb 18, 2025 - Jun 24, 2025
#6-26.72%
Jul 22, 2011 - Jan 27, 2012		-23.64%
Aug 29, 2018 - Apr 12, 2019
#7-22.71%
Dec 6, 2007 - Jul 15, 2008		-16.87%
Jul 10, 2024 - Dec 16, 2024
#8-21.93%
Feb 27, 2006 - Aug 8, 2007		-16.10%
Jun 2, 2026 - Jul 29, 2026
#9-15.10%
Sep 21, 2012 - Jan 14, 2013		-14.88%
Dec 4, 2015 - Jul 12, 2016
#10-14.51%
Jan 29, 2018 - Jun 5, 2018		-14.63%
May 21, 2015 - Nov 2, 2015
#11-13.70%
Jul 20, 2020 - Oct 12, 2020		-14.13%
Apr 2, 2012 - Apr 30, 2013
#12-13.36%
Oct 2, 2013 - Jan 7, 2014		-13.80%
Oct 29, 2025 - Apr 14, 2026
#13-13.21%
Mar 19, 2015 - May 29, 2015		-11.29%
Sep 2, 2020 - Dec 1, 2020
#14-11.51%
Jan 21, 2014 - Feb 20, 2014		-10.79%
Jan 26, 2018 - Mar 9, 2018
#15-10.38%
May 30, 2013 - Jul 10, 2013		-10.02%
Jul 19, 2007 - Sep 27, 2007

Correlation

Correlation between XBI and IXN is 0.79 which considered as a strong positive correlation - the stocks tend to move together.

0.79
-101

Dividend Comparison (2004 - 2026)

XBI vs IXN dividend yield comparison.

YearXBIIXN
20260.09%0.12%
20250.37%1.04%
20240.15%0.43%
20230.02%0.55%
20220.00%0.81%
20210.04%0.58%
20200.20%0.63%
20190.00%1.06%
20180.28%0.94%
20170.24%0.93%
20160.26%1.03%
20150.61%1.12%
20141.07%1.14%
20130.17%1.02%
20120.22%1.08%
20110.00%0.99%
20100.00%0.67%
20090.28%0.61%
20081.27%1.19%
20070.26%0.36%
20060.00%0.22%
20050.00%0.05%
20040.00%1.21%

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