IBBQ vs XBI
Comparison between INVESCO NASDAQ BIOTECHNOLOGY ETF (IBBQ, ETF) and STATE STREET(R) SPDR(R) S&P(R) BIOTECH ETF (XBI, ETF).
Both IBBQ and XBI are from the Healthcare sector.
5-Year PerformanceIBBQ has outperformed XBI, delivering a return of +5.7% compared to +3.6%
IBBQ vs XBI - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
IBBQ
$73M
Winner
XBI
$11B
Expense Ratio
Winner
IBBQ
0.19%
XBI
0.35%
Max Drawdown
Winner
IBBQ
38.42%
XBI
63.90%
Sharpe Ratio
IBBQ
1.93
Winner
XBI
2.20
5Y Beta
Winner
IBBQ
0.74
XBI
0.96
P/E Ratio
Winner
IBBQ
-44.37
XBI
-8.67
Forward P/E
IBBQ
16.58
XBI
N/A
5Y Dividends CAGR
IBBQ
N/A
XBI
12.45%
5Y EPS CAGR
Winner
IBBQ
16.81%
XBI
5.09%
Debt to Equity
IBBQ
68.74%
Winner
XBI
28.92%
P/S Ratio
Winner
IBBQ
7.10
XBI
9.63
P/B Ratio
Winner
IBBQ
5.18
XBI
5.25
IBBQ vs XBI - Holdings Comparison
IBBQ and XBI have 117 common holdings. Overlap is 40.57%
IBBQ's top 25 holdings weight is 60.46%. XBI's top 25 holdings weight is 31.55%.
| Rank | IBBQ | XBI |
|---|---|---|
| #1 | VERTEX PHARMACEUTICALS INC (VRTX) - 7.87% | APOGEE THERAPEUTICS INC (APGE) - 1.55% |
| #2 | AMGEN INC (AMGN) - 7.85% | ERASCA INC (ERAS) - 1.52% |
| #3 | GILEAD SCIENCES INC (GILD) - 7.23% | MODERNA INC (MRNA) - 1.42% |
| #4 | REGENERON PHARMACEUTICALS INC (REGN) - 4.82% | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 1.39% |
| #5 | REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 2.76% | TWIST BIOSCIENCE CORP (TWST) - 1.31% |
| #6 | ALNYLAM PHARMACEUTICALS INC (ALNY) - 2.62% | VIKING THERAPEUTICS INC (VKTX) - 1.30% |
| #7 | BIOGEN INC (BIIB) - 2.05% | SPYRE THERAPEUTICS INC (SYRE) - 1.30% |
| #8 | ILLUMINA INC (ILMN) - 1.99% | ORUKA THERAPEUTICS INC (ORKA) - 1.29% |
| #9 | MODERNA INC (MRNA) - 1.91% | CG ONCOLOGY INC (CGON) - 1.27% |
| #10 | ROIVANT SCIENCES LTD ORDINARY SHARES (ROIV) - 1.77% | n/a (PRAX) - 1.26% |
| #11 | ROYALTY PHARMA PLC CLASS A (RPRX) - 1.76% | DIANTHUS THERAPEUTICS INC (DNTH) - 1.25% |
| #12 | ARGENX SE ADR (ARGX) - 1.68% | MIRUM PHARMACEUTICALS INC (MIRM) - 1.23% |
| #13 | INSMED INC (INSM) - 1.68% | REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.22% |
| #14 | INCYTE CORP (INCY) - 1.62% | NATERA INC (NTRA) - 1.22% |
| #15 | UNITED THERAPEUTICS CORP (UTHR) - 1.59% | RHYTHM PHARMACEUTICALS INC (RYTM) - 1.22% |
| #16 | GUARDANT HEALTH INC (GH) - 1.52% | PROTAGONIST THERAPEUTICS INC (PTGX) - 1.22% |
| #17 | VIATRIS INC (VTRS) - 1.37% | COGENT BIOSCIENCES INC (COGT) - 1.20% |
| #18 | NEUROCRINE BIOSCIENCES INC (NBIX) - 1.22% | VAXCYTE INC ORDINARY SHARES (PCVX) - 1.19% |
| #19 | ASCENDIS PHARMA AS (ASND) - 1.16% | RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 1.18% |
| #20 | BRIDGEBIO PHARMA INC (BBIO) - 1.14% | CYTOKINETICS INC (CYTK) - 1.18% |
| #21 | MEDPACE HOLDINGS INC (MEDP) - 1.06% | BRIDGEBIO PHARMA INC (BBIO) - 1.17% |
| #22 | JAZZ PHARMACEUTICALS PLC (JAZZ) - 1.06% | ROIVANT SCIENCES LTD ORDINARY SHARES (ROIV) - 1.17% |
| #23 | EXELIXIS INC (EXEL) - 0.98% | SCHOLAR ROCK HOLDING CORP (SRRK) - 1.17% |
| #24 | MADRIGAL PHARMACEUTICALS INC (MDGL) - 0.89% | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 1.16% |
| #25 | AXSOME THERAPEUTICS INC (AXSM) - 0.86% | TG THERAPEUTICS INC (TGTX) - 1.16% |
| Total Holdings | 258 | 157 |
IBBQ vs XBI - Historical Returns
Returns include dividend reinvestment.
1M
Winner
IBBQ
+6.92%
XBI
+5.92%
3M
IBBQ
+8.65%
Winner
XBI
+13.39%
6M
IBBQ
+10.81%
Winner
XBI
+20.65%
1Y
IBBQ
+50.50%
Winner
XBI
+80.72%
5Y(CAGR)
Winner
IBBQ
+5.69%
XBI
+3.60%
10Y(CAGR)
IBBQ
N/A
XBI
+10.28%
Max(CAGR)
IBBQ
+5.82%
Winner
XBI
+11.89%
IBBQ vs XBI - Annual Returns (2006 - 2026)
Returns include dividend reinvestment.
| Year | IBBQ | XBI |
|---|---|---|
| 2026 | +15.20% | +27.26% |
| 2025 | +32.76% | +33.70% |
| 2024 | -2.37% | -0.05% |
| 2023 | +5.49% | +9.54% |
| 2022 | -10.89% | -28.10% |
| 2021 | -6.71% | -20.55% |
| 2020 | N/A | +49.01% |
| 2019 | N/A | +30.54% |
| 2018 | N/A | -17.55% |
| 2017 | N/A | +42.81% |
| 2016 | N/A | -12.49% |
| 2015 | N/A | +12.40% |
| 2014 | N/A | +44.27% |
| 2013 | N/A | +42.97% |
| 2012 | N/A | +32.95% |
| 2011 | N/A | +3.91% |
| 2010 | N/A | +15.74% |
| 2009 | N/A | -0.82% |
| 2008 | N/A | -8.58% |
| 2007 | N/A | +30.24% |
| 2006 | N/A | -6.48% |
IBBQ vs XBI Drawdown Comparison
The maximum drawdown for IBBQ was -37.94%, occurring on Jun 13, 2022. Recovery took 1062 trading sessions.
The maximum drawdown for XBI was -63.89%, occurring on May 11, 2022. This drawdown has not yet recovered.
The current IBBQ drawdown is -4.65%. The current XBI drawdown is -10.63%.
| Rank | IBBQ | XBI |
|---|---|---|
| #1 | -37.94% Aug 9, 2021 - Oct 30, 2025 | -63.89% Feb 8, 2021 - May 11, 2022 |
| #2 | -8.34% Feb 24, 2026 - Apr 14, 2026 | -49.25% Jul 17, 2015 - Jan 12, 2018 |
| #3 | -6.82% Apr 17, 2026 - Jun 22, 2026 | -37.67% Aug 14, 2008 - Apr 14, 2011 |
| #4 | -6.32% Jul 7, 2026 - Jul 20, 2026 | -35.26% Jun 20, 2018 - May 11, 2020 |
| #5 | -4.66% Jul 1, 2021 - Aug 3, 2021 | -29.06% Feb 27, 2014 - Oct 28, 2014 |
| #6 | -3.73% Jan 22, 2026 - Feb 24, 2026 | -26.72% Jul 22, 2011 - Jan 27, 2012 |
| #7 | -3.65% Nov 28, 2025 - Dec 22, 2025 | -22.71% Dec 6, 2007 - Jul 15, 2008 |
| #8 | -3.53% Dec 24, 2025 - Jan 7, 2026 | -21.93% Feb 27, 2006 - Aug 8, 2007 |
| #9 | -3.00% Jan 7, 2026 - Jan 22, 2026 | -15.10% Sep 21, 2012 - Jan 14, 2013 |
| #10 | -2.38% Jun 11, 2021 - Jun 25, 2021 | -14.51% Jan 29, 2018 - Jun 5, 2018 |
| #11 | -2.06% Oct 31, 2025 - Nov 10, 2025 | -13.70% Jul 20, 2020 - Oct 12, 2020 |
| #12 | -1.85% Nov 18, 2025 - Nov 24, 2025 | -13.36% Oct 2, 2013 - Jan 7, 2014 |
| #13 | -1.32% Aug 5, 2021 - Aug 9, 2021 | -13.21% Mar 19, 2015 - May 29, 2015 |
| #14 | -0.71% Apr 15, 2026 - Apr 17, 2026 | -11.51% Jan 21, 2014 - Feb 20, 2014 |
| #15 | -0.48% Dec 22, 2025 - Dec 24, 2025 | -10.38% May 30, 2013 - Jul 10, 2013 |
Correlation
Correlation between IBBQ and XBI is 0.93 which considered as a very strong positive correlation - the stocks move almost identically together.
0.93
-101
Dividend Comparison (2007 - 2026)
IBBQ vs XBI dividend yield comparison.
| Year | IBBQ | XBI |
|---|---|---|
| 2026 | 0.22% | 0.09% |
| 2025 | 0.90% | 0.37% |
| 2024 | 1.14% | 0.15% |
| 2023 | 0.81% | 0.02% |
| 2022 | 0.76% | 0.00% |
| 2021 | 0.63% | 0.04% |
| 2020 | 0.00% | 0.20% |
| 2019 | 0.00% | 0.00% |
| 2018 | 0.00% | 0.28% |
| 2017 | 0.00% | 0.24% |
| 2016 | 0.00% | 0.26% |
| 2015 | 0.00% | 0.61% |
| 2014 | 0.00% | 1.07% |
| 2013 | 0.00% | 0.17% |
| 2012 | 0.00% | 0.22% |
| 2009 | 0.00% | 0.28% |
| 2008 | 0.00% | 1.27% |
| 2007 | 0.00% | 0.26% |
Select Stocks to Compare
Popular: IBBQ vs SPYXBI vs SPY
More Comparisons
Compare with similar stocks