XBI vs EZU
Comparison between STATE STREET(R) SPDR(R) S&P(R) BIOTECH ETF (XBI, ETF) and ISHARES MSCI EUROZONE ETF (EZU, ETF).
5-Year PerformanceEZU has outperformed XBI, delivering a return of +10.4% compared to +4.5%
XBI vs EZU - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
XBI
$9.60B
EZU
$9.60B
Expense Ratio
Winner
XBI
0.35%
EZU
0.50%
Max Drawdown
Winner
XBI
63.90%
EZU
67.97%
Sharpe Ratio
Winner
XBI
2.24
EZU
1.14
5Y Beta
XBI
0.97
Winner
EZU
0.79
P/E Ratio
XBI
-9.20
EZU
N/A
5Y Dividends CAGR
XBI
12.45%
Winner
EZU
16.52%
5Y EPS CAGR
XBI
6.71%
EZU
N/A
Debt to Equity
XBI
36.66%
EZU
N/A
P/S Ratio
XBI
9.00
EZU
N/A
P/B Ratio
XBI
4.96
EZU
N/A
XBI vs EZU - Holdings Comparison
XBI and EZU have 1 common holdings. Overlap is -0.04%
XBI's top 25 holdings weight is 31.60%. EZU's top 25 holdings weight is 50.81%.
| Rank | XBI | EZU |
|---|---|---|
| #1 | APOGEE THERAPEUTICS INC (APGE) - 1.61% | ASML HOLDING NV (n/a) - 9.89% |
| #2 | ORUKA THERAPEUTICS INC (ORKA) - 1.42% | SIEMENS AG (n/a) - 3.09% |
| #3 | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 1.41% | BANCO SANTANDER SA (n/a) - 2.56% |
| #4 | ERASCA INC (ERAS) - 1.39% | ALLIANZ SE (n/a) - 2.33% |
| #5 | DIANTHUS THERAPEUTICS INC (DNTH) - 1.31% | SCHNEIDER ELECTRIC SE (n/a) - 2.32% |
| #6 | VIKING THERAPEUTICS INC (VKTX) - 1.30% | SAP SE (n/a) - 2.07% |
| #7 | SPYRE THERAPEUTICS INC (SYRE) - 1.28% | TOTALENERGIES SE (TTE:XPAR) - 1.98% |
| #8 | TWIST BIOSCIENCE CORP (TWST) - 1.28% | IBERDROLA SA (n/a) - 1.97% |
| #9 | MODERNA INC (MRNA) - 1.28% | SIEMENS ENERGY AG ORDINARY SHARES (n/a) - 1.90% |
| #10 | CG ONCOLOGY INC (CGON) - 1.27% | BANCO BILBAO VIZCAYA ARGENTARIA SA (n/a) - 1.82% |
| #11 | PROTAGONIST THERAPEUTICS INC (PTGX) - 1.26% | LVMH MOET HENNESSY LOUIS VUITTON SE (n/a) - 1.78% |
| #12 | n/a (PRAX) - 1.25% | SAFRAN SA (n/a) - 1.76% |
| #13 | REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.24% | AIRBUS SE (n/a) - 1.71% |
| #14 | MIRUM PHARMACEUTICALS INC (MIRM) - 1.23% | AIR LIQUIDE SA (n/a) - 1.63% |
| #15 | RHYTHM PHARMACEUTICALS INC (RYTM) - 1.21% | INFINEON TECHNOLOGIES AG (n/a) - 1.58% |
| #16 | COGENT BIOSCIENCES INC (COGT) - 1.21% | UNICREDIT SPA (n/a) - 1.57% |
| #17 | VAXCYTE INC ORDINARY SHARES (PCVX) - 1.21% | BNP PARIBAS ACT. CAT.A (n/a) - 1.50% |
| #18 | RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 1.20% | L'OREAL SA (n/a) - 1.36% |
| #19 | NATERA INC (NTRA) - 1.20% | INTESA SANPAOLO (n/a) - 1.24% |
| #20 | ROIVANT SCIENCES LTD ORDINARY SHARES (ROIV) - 1.19% | DEUTSCHE TELEKOM AG (n/a) - 1.21% |
| #21 | BRIDGEBIO PHARMA INC (BBIO) - 1.19% | SANOFI SA (n/a) - 1.21% |
| #22 | ALKERMES PLC (ALKS) - 1.17% | ING GROEP NV (n/a) - 1.20% |
| #23 | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 1.17% | ENEL SPA (n/a) - 1.14% |
| #24 | CYTOKINETICS INC (CYTK) - 1.17% | AXA SA (n/a) - 1.02% |
| #25 | INSMED INC (INSM) - 1.15% | ANHEUSER-BUSCH INBEV SA/NV (n/a) - 0.97% |
| Total Holdings | 156 | 227 |
XBI vs EZU - Historical Returns
Returns include dividend reinvestment.
1M
XBI
-3.97%
Winner
EZU
+3.97%
3M
Winner
XBI
+17.85%
EZU
+8.40%
6M
Winner
XBI
+25.50%
EZU
+8.15%
1Y
Winner
XBI
+85.27%
EZU
+23.54%
5Y(CAGR)
XBI
+4.46%
Winner
EZU
+10.36%
10Y(CAGR)
XBI
+9.75%
Winner
EZU
+10.77%
Max(CAGR)
Winner
XBI
+11.96%
EZU
+5.34%
XBI vs EZU - Annual Returns (2001 - 2026)
Returns include dividend reinvestment.
| Year | XBI | EZU |
|---|---|---|
| 2026 | +29.62% | +12.05% |
| 2025 | +33.70% | +41.08% |
| 2024 | -0.05% | +3.71% |
| 2023 | +9.54% | +21.81% |
| 2022 | -28.10% | -18.04% |
| 2021 | -20.55% | +12.61% |
| 2020 | +49.01% | +6.29% |
| 2019 | +30.54% | +23.88% |
| 2018 | -17.55% | -17.16% |
| 2017 | +42.81% | +27.62% |
| 2016 | -12.49% | +3.55% |
| 2015 | +12.40% | -1.76% |
| 2014 | +44.27% | -7.62% |
| 2013 | +42.97% | +26.14% |
| 2012 | +32.95% | +19.92% |
| 2011 | +3.91% | -18.64% |
| 2010 | +15.74% | -5.69% |
| 2009 | -0.82% | +24.52% |
| 2008 | -8.58% | -45.63% |
| 2007 | +30.24% | +17.77% |
| 2006 | -6.48% | +30.87% |
| 2005 | N/A | +9.23% |
| 2004 | N/A | +19.83% |
| 2003 | N/A | +38.67% |
| 2002 | N/A | -22.54% |
| 2001 | N/A | -22.44% |
XBI vs EZU Drawdown Comparison
The maximum drawdown for XBI was -63.89%, occurring on May 11, 2022. This drawdown has not yet recovered.
The maximum drawdown for EZU was -65.34%, occurring on Mar 9, 2009. Recovery took 2568 trading sessions.
The current XBI drawdown is -8.97%.
| Rank | XBI | EZU |
|---|---|---|
| #1 | -63.89% Feb 8, 2021 - May 11, 2022 | -65.34% Oct 31, 2007 - Jan 12, 2018 |
| #2 | -49.25% Jul 17, 2015 - Jan 12, 2018 | -50.74% Jan 3, 2001 - Dec 23, 2004 |
| #3 | -37.67% Aug 14, 2008 - Apr 14, 2011 | -41.36% Jan 26, 2018 - Dec 2, 2020 |
| #4 | -35.26% Jun 20, 2018 - May 11, 2020 | -36.06% Sep 2, 2021 - Feb 21, 2024 |
| #5 | -29.06% Feb 27, 2014 - Oct 28, 2014 | -15.08% May 10, 2006 - Sep 28, 2006 |
| #6 | -26.72% Jul 22, 2011 - Jan 27, 2012 | -15.02% Mar 18, 2025 - May 2, 2025 |
| #7 | -22.71% Dec 6, 2007 - Jul 15, 2008 | -13.70% Jul 17, 2007 - Oct 9, 2007 |
| #8 | -21.93% Feb 27, 2006 - Aug 8, 2007 | -13.06% Feb 25, 2026 - Jun 2, 2026 |
| #9 | -15.10% Sep 21, 2012 - Jan 14, 2013 | -10.97% Sep 27, 2024 - Feb 13, 2025 |
| #10 | -14.51% Jan 29, 2018 - Jun 5, 2018 | -9.22% May 15, 2024 - Sep 26, 2024 |
| #11 | -13.70% Jul 20, 2020 - Oct 12, 2020 | -8.62% Mar 8, 2005 - Aug 2, 2005 |
| #12 | -13.36% Oct 2, 2013 - Jan 7, 2014 | -7.65% Feb 26, 2007 - Mar 30, 2007 |
| #13 | -13.21% Mar 19, 2015 - May 29, 2015 | -7.08% Jun 15, 2021 - Aug 13, 2021 |
| #14 | -11.51% Jan 21, 2014 - Feb 20, 2014 | -6.86% Sep 9, 2005 - Dec 12, 2005 |
| #15 | -10.38% May 30, 2013 - Jul 10, 2013 | -5.77% Nov 12, 2025 - Dec 10, 2025 |
Correlation
Correlation between XBI and EZU is 0.75 which considered as a strong positive correlation - the stocks tend to move together.
0.75
-101
Dividend Comparison (2001 - 2026)
XBI vs EZU dividend yield comparison.
| Year | XBI | EZU |
|---|---|---|
| 2026 | 0.09% | 1.72% |
| 2025 | 0.37% | 2.85% |
| 2024 | 0.15% | 2.90% |
| 2023 | 0.02% | 2.56% |
| 2022 | 0.00% | 2.79% |
| 2021 | 0.04% | 2.46% |
| 2020 | 0.20% | 2.13% |
| 2019 | 0.00% | 2.84% |
| 2018 | 0.28% | 3.47% |
| 2017 | 0.24% | 1.91% |
| 2016 | 0.26% | 3.07% |
| 2015 | 0.61% | 2.18% |
| 2014 | 1.07% | 2.97% |
| 2013 | 0.17% | 2.23% |
| 2012 | 0.22% | 2.73% |
| 2011 | 0.00% | 4.18% |
| 2010 | 0.00% | 2.61% |
| 2009 | 0.28% | 2.79% |
| 2008 | 1.27% | 7.69% |
| 2007 | 0.26% | 2.48% |
| 2006 | 0.00% | 1.79% |
| 2005 | 0.00% | 1.70% |
| 2004 | 0.00% | 1.79% |
| 2003 | 0.00% | 1.38% |
| 2002 | 0.00% | 1.03% |
| 2001 | 0.00% | 1.19% |
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