USEW vs SBIO
Comparison between Cambria US EW ETF (USEW, ETF) and ALPS MEDICAL BREAKTHROUGHS ETF (SBIO, ETF).
USEW vs SBIO - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
USEW
$190M
Winner
SBIO
$190M
Expense Ratio
Winner
USEW
0.30%
SBIO
0.50%
Max Drawdown
Winner
USEW
8.25%
SBIO
63.06%
Sharpe Ratio
USEW
1.18
Winner
SBIO
2.26
5Y Beta
Winner
USEW
0.88
SBIO
1.01
P/E Ratio
USEW
N/A
SBIO
-5.74
5Y Dividends CAGR
USEW
N/A
SBIO
9.24%
Debt to Equity
USEW
N/A
SBIO
0.42%
P/S Ratio
USEW
N/A
SBIO
8.00
P/B Ratio
USEW
N/A
SBIO
4.14
USEW vs SBIO - Holdings Comparison
USEW and SBIO have 3 common holdings. Overlap is 0.02%
USEW's top 25 holdings weight is 48.80%. SBIO's top 25 holdings weight is 56.86%.
| Rank | USEW | SBIO |
|---|---|---|
| #1 | INVESCO S&P 500® LOW VOLATILITY ETF (SPLV) - 6.64% | CRINETICS PHARMACEUTICALS INC (CRNX) - 4.38% |
| #2 | STATE STREET® SPDR® S&P 500® ETF (SPY) - 4.04% | APOGEE THERAPEUTICS INC (APGE) - 4.11% |
| #3 | NVIDIA CORP (NVDA) - 3.44% | XENON PHARMACEUTICALS INC (XENE) - 3.41% |
| #4 | MICROSOFT CORP (MSFT) - 3.34% | CG ONCOLOGY INC (CGON) - 3.22% |
| #5 | APPLE INC (AAPL) - 3.01% | DIANTHUS THERAPEUTICS INC (DNTH) - 2.72% |
| #6 | INVESCO QQQ TRUST (QQQ) - 2.88% | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 2.70% |
| #7 | FIDELITY VALUE FACTOR ETF (FVAL) - 2.74% | ORUKA THERAPEUTICS INC (ORKA) - 2.65% |
| #8 | VANGUARD S&P 500 ETF (VOO) - 2.46% | n/a (DFTX) - 2.63% |
| #9 | ISHARES RUSSELL 1000 VALUE ETF (IWD) - 1.89% | VERADERMICS INC (MANE) - 2.59% |
| #10 | n/a (MDYV) - 1.86% | EDGEWISE THERAPEUTICS INC (EWTX) - 2.59% |
| #11 | INVESCO S&P 500® EQUAL WEIGHT ETF (RSP) - 1.83% | ACADIA PHARMACEUTICALS INC (ACAD) - 2.25% |
| #12 | VANGUARD TOTAL STOCK MARKET ETF (VTI) - 1.68% | RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 2.25% |
| #13 | ALPHABET INC CLASS C (GOOG) - 1.67% | DENALI THERAPEUTICS INC (DNLI) - 2.15% |
| #14 | INVESCO S&P GLOBAL WATER ETF (CGW) - 1.55% | NEWAMSTERDAM PHARMA CO NV (NAMS) - 2.09% |
| #15 | AMAZON.COM INC (AMZN) - 1.53% | DYNE THERAPEUTICS INC ORDINARY SHARES (DYN) - 2.00% |
| #16 | META PLATFORMS INC CLASS A (META) - 1.46% | STRUCTURE THERAPEUTICS INC ADR (GPCR) - 1.95% |
| #17 | BERKSHIRE HATHAWAY INC CLASS B (BRK-B) - 1.46% | IDEAYA BIOSCIENCES INC (IDYA) - 1.63% |
| #18 | BROADCOM INC (AVGO) - 1.37% | MBX BIOSCIENCES INC (MBX) - 1.55% |
| #19 | VANGUARD VALUE ETF (VTV) - 1.25% | VERA THERAPEUTICS INC CLASS A (VERA) - 1.52% |
| #20 | PROSHARES S&P 500 DIVIDEND ARISTOCRATS (NOBL) - 1.12% | CELLDEX THERAPEUTICS INC (CLDX) - 1.52% |
| #21 | n/a (SHOP) - 0.33% | DISC MEDICINE INC ORDINARY SHARES (IRON) - 1.50% |
| #22 | ISHARES CORE S&P MID-CAP ETF (IJH) - 0.32% | n/a (TARS) - 1.37% |
| #23 | ISHARES MSCI USA MOMENTUM FACTOR ETF (MTUM) - 0.32% | BIOCRYST PHARMACEUTICALS INC (BCRX) - 1.36% |
| #24 | ISHARES MSCI USA MIN VOL FACTOR ETF (USMV) - 0.31% | KAILERA THERAPEUTICS INC (KLRA) - 1.36% |
| #25 | AMERICAN EXPRESS CO (AXP) - 0.30% | IMMUNOME INC ORDINARY SHARES (IMNM) - 1.36% |
| Total Holdings | 557 | 107 |
USEW vs SBIO - Historical Returns
Returns include dividend reinvestment.
1M
USEW
+0.17%
Winner
SBIO
+10.77%
3M
USEW
+6.10%
Winner
SBIO
+16.31%
6M
USEW
+8.53%
Winner
SBIO
+22.65%
1Y
USEW
N/A
SBIO
+99.16%
5Y(CAGR)
USEW
N/A
SBIO
+7.32%
10Y(CAGR)
USEW
N/A
SBIO
+11.27%
Max(CAGR)
Winner
USEW
+18.92%
SBIO
+9.47%
USEW vs SBIO - Annual Returns (2014 - 2026)
Returns include dividend reinvestment.
| Year | USEW | SBIO |
|---|---|---|
| 2026 | +9.76% | +29.55% |
| 2025 | +0.77% | +53.69% |
| 2024 | N/A | +4.25% |
| 2023 | N/A | +11.05% |
| 2022 | N/A | -30.19% |
| 2021 | N/A | -17.90% |
| 2020 | N/A | +23.09% |
| 2019 | N/A | +47.58% |
| 2018 | N/A | -13.24% |
| 2017 | N/A | +44.12% |
| 2016 | N/A | -25.20% |
| 2015 | N/A | +26.42% |
| 2014 | N/A | +0.00% |
USEW vs SBIO Drawdown Comparison
The maximum drawdown for USEW was -7.85%, occurring on Mar 30, 2026. Recovery took 54 trading sessions.
The maximum drawdown for SBIO was -63.06%, occurring on Oct 27, 2023. Recovery took 1350 trading sessions.
The current USEW drawdown is -1.01%. The current SBIO drawdown is -5.74%.
| Rank | USEW | SBIO |
|---|---|---|
| #1 | -7.85% Jan 27, 2026 - Apr 15, 2026 | -63.06% Feb 8, 2021 - Jun 25, 2026 |
| #2 | -3.00% Jun 4, 2026 - Jun 15, 2026 | -49.69% Jul 17, 2015 - Jun 6, 2018 |
| #3 | -2.03% Jan 12, 2026 - Jan 27, 2026 | -39.30% Dec 24, 2019 - Jun 23, 2020 |
| #4 | -1.83% Jul 10, 2026 - Jul 20, 2026 | -32.42% Sep 28, 2018 - Nov 25, 2019 |
| #5 | -1.62% May 14, 2026 - May 22, 2026 | -13.78% Apr 23, 2015 - May 20, 2015 |
| #6 | -1.45% Jun 15, 2026 - Jun 30, 2026 | -13.03% Jun 23, 2020 - Oct 7, 2020 |
| #7 | -1.25% Dec 24, 2025 - Jan 6, 2026 | -11.31% Mar 19, 2015 - Apr 13, 2015 |
| #8 | -1.02% Jul 6, 2026 - Jul 10, 2026 | -7.98% Jul 9, 2026 - Jul 16, 2026 |
| #9 | -0.79% May 6, 2026 - May 14, 2026 | -6.72% Jun 6, 2018 - Sep 28, 2018 |
| #10 | -0.67% Jan 6, 2026 - Jan 9, 2026 | -6.30% Jan 27, 2015 - Feb 17, 2015 |
| #11 | -0.63% Apr 17, 2026 - Apr 30, 2026 | -6.29% Jun 22, 2015 - Jul 13, 2015 |
| #12 | -0.48% May 1, 2026 - May 5, 2026 | -6.19% Dec 22, 2020 - Jan 7, 2021 |
| #13 | -0.42% Jun 2, 2026 - Jun 4, 2026 | -4.88% Oct 13, 2020 - Oct 27, 2020 |
| #14 | -0.21% Jun 30, 2026 - Jul 6, 2026 | -3.81% Jan 14, 2015 - Jan 20, 2015 |
| #15 | -0.11% May 26, 2026 - May 28, 2026 | -3.39% Oct 27, 2020 - Nov 4, 2020 |
Correlation
Correlation between USEW and SBIO is 0.80 which considered as a strong positive correlation - the stocks tend to move together.
0.80
-101
Dividend Comparison (2017 - 2026)
USEW vs SBIO dividend yield comparison.
| Year | USEW | SBIO |
|---|---|---|
| 2026 | 0.44% | 0.00% |
| 2025 | 0.13% | 0.00% |
| 2024 | 0.00% | 3.55% |
| 2023 | 0.00% | 0.22% |
| 2019 | 0.00% | 0.04% |
| 2018 | 0.00% | 2.79% |
| 2017 | 0.00% | 1.77% |
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