SBIO vs ADPV
Comparison between ALPS MEDICAL BREAKTHROUGHS ETF (SBIO, ETF) and ADAPTIV SELECT ETF (ADPV, ETF).
SBIO vs ADPV - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
Winner
SBIO
$190M
ADPV
$190M
Expense Ratio
Winner
SBIO
0.50%
ADPV
1.00%
Max Drawdown
SBIO
63.06%
Winner
ADPV
22.30%
Sharpe Ratio
Winner
SBIO
2.26
ADPV
0.54
5Y Beta
SBIO
1.01
Winner
ADPV
0.76
P/E Ratio
Winner
SBIO
-5.74
ADPV
163.17
Forward P/E
SBIO
N/A
ADPV
15.24
PEG Ratio
SBIO
N/A
ADPV
-1.85
5Y Dividends CAGR
SBIO
9.24%
ADPV
N/A
Debt to Equity
SBIO
0.42%
Winner
ADPV
-116.72%
P/S Ratio
SBIO
8.00
Winner
ADPV
0.99
P/B Ratio
SBIO
4.14
Winner
ADPV
2.37
SBIO vs ADPV - Holdings Comparison
SBIO and ADPV have 1 common holdings. Overlap is 0.00%
SBIO's top 25 holdings weight is 56.86%. ADPV's top 25 holdings weight is 98.01%.
| Rank | SBIO | ADPV |
|---|---|---|
| #1 | CRINETICS PHARMACEUTICALS INC (CRNX) - 4.38% | INTEL CORP (INTC) - 6.09% |
| #2 | APOGEE THERAPEUTICS INC (APGE) - 4.11% | HEWLETT PACKARD ENTERPRISE CO (HPE) - 4.93% |
| #3 | XENON PHARMACEUTICALS INC (XENE) - 3.41% | VIAVI SOLUTIONS INC (VIAV) - 4.82% |
| #4 | CG ONCOLOGY INC (CGON) - 3.22% | TERAWULF INC (WULF) - 4.39% |
| #5 | DIANTHUS THERAPEUTICS INC (DNTH) - 2.72% | ROIVANT SCIENCES LTD ORDINARY SHARES (ROIV) - 4.36% |
| #6 | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 2.70% | INVESCO LTD (IVZ) - 4.30% |
| #7 | ORUKA THERAPEUTICS INC (ORKA) - 2.65% | VIATRIS INC (VTRS) - 4.27% |
| #8 | n/a (DFTX) - 2.63% | HEALTHCARE REALTY TRUST INC (HR) - 4.18% |
| #9 | VERADERMICS INC (MANE) - 2.59% | MILLICOM INTERNATIONAL CELLULAR SA (TIGO) - 4.17% |
| #10 | EDGEWISE THERAPEUTICS INC (EWTX) - 2.59% | ARROWHEAD PHARMACEUTICALS INC (ARWR) - 4.10% |
| #11 | ACADIA PHARMACEUTICALS INC (ACAD) - 2.25% | HOST HOTELS & RESORTS INC (HST) - 3.93% |
| #12 | RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 2.25% | CENTENE CORP (CNC) - 3.89% |
| #13 | DENALI THERAPEUTICS INC (DNLI) - 2.15% | ELEMENT SOLUTIONS INC (ESI) - 3.81% |
| #14 | NEWAMSTERDAM PHARMA CO NV (NAMS) - 2.09% | TFS FINANCIAL CORP (TFSL) - 3.81% |
| #15 | DYNE THERAPEUTICS INC ORDINARY SHARES (DYN) - 2.00% | ANTERO MIDSTREAM CORP (AM) - 3.64% |
| #16 | STRUCTURE THERAPEUTICS INC ADR (GPCR) - 1.95% | TECHNIPFMC PLC (FTI) - 3.56% |
| #17 | IDEAYA BIOSCIENCES INC (IDYA) - 1.63% | NOV INC (NOV) - 3.49% |
| #18 | MBX BIOSCIENCES INC (MBX) - 1.55% | CENTRAL BANCOMPANY INC CLASS A (CBC) - 3.47% |
| #19 | VERA THERAPEUTICS INC CLASS A (VERA) - 1.52% | FORD MOTOR CO (F) - 3.43% |
| #20 | CELLDEX THERAPEUTICS INC (CLDX) - 1.52% | MDU RESOURCES GROUP INC (MDU) - 3.35% |
| #21 | DISC MEDICINE INC ORDINARY SHARES (IRON) - 1.50% | PERMIAN RESOURCES CORP CLASS A (PR) - 3.34% |
| #22 | n/a (TARS) - 1.37% | HALLIBURTON CO (HAL) - 3.32% |
| #23 | BIOCRYST PHARMACEUTICALS INC (BCRX) - 1.36% | INGRAM MICRO HOLDING CORP (INGM) - 3.21% |
| #24 | KAILERA THERAPEUTICS INC (KLRA) - 1.36% | APA CORP (APA) - 3.15% |
| #25 | IMMUNOME INC ORDINARY SHARES (IMNM) - 1.36% | MACY'S INC (M) - 3.00% |
| Total Holdings | 107 | 28 |
SBIO vs ADPV - Historical Returns
Returns include dividend reinvestment.
1M
Winner
SBIO
+10.77%
ADPV
-4.60%
3M
Winner
SBIO
+16.31%
ADPV
+9.38%
6M
Winner
SBIO
+22.65%
ADPV
+1.10%
1Y
Winner
SBIO
+99.16%
ADPV
+17.55%
5Y(CAGR)
SBIO
+7.32%
ADPV
N/A
10Y(CAGR)
SBIO
+11.27%
ADPV
N/A
Max(CAGR)
SBIO
+9.47%
Winner
ADPV
+18.75%
SBIO vs ADPV - Annual Returns (2014 - 2026)
Returns include dividend reinvestment.
| Year | SBIO | ADPV |
|---|---|---|
| 2026 | +29.55% | +6.33% |
| 2025 | +53.69% | +19.47% |
| 2024 | +4.25% | +47.93% |
| 2023 | +11.05% | -0.71% |
| 2022 | -30.19% | +0.57% |
| 2021 | -17.90% | N/A |
| 2020 | +23.09% | N/A |
| 2019 | +47.58% | N/A |
| 2018 | -13.24% | N/A |
| 2017 | +44.12% | N/A |
| 2016 | -25.20% | N/A |
| 2015 | +26.42% | N/A |
| 2014 | +0.00% | N/A |
SBIO vs ADPV Drawdown Comparison
The maximum drawdown for SBIO was -63.06%, occurring on Oct 27, 2023. Recovery took 1350 trading sessions.
The maximum drawdown for ADPV was -22.30%, occurring on Mar 10, 2025. Recovery took 147 trading sessions.
The current SBIO drawdown is -5.74%. The current ADPV drawdown is -4.72%.
| Rank | SBIO | ADPV |
|---|---|---|
| #1 | -63.06% Feb 8, 2021 - Jun 25, 2026 | -22.30% Feb 18, 2025 - Sep 18, 2025 |
| #2 | -49.69% Jul 17, 2015 - Jun 6, 2018 | -14.73% Jul 18, 2023 - Feb 8, 2024 |
| #3 | -39.30% Dec 24, 2019 - Jun 23, 2020 | -13.88% Oct 14, 2025 - Jan 6, 2026 |
| #4 | -32.42% Sep 28, 2018 - Nov 25, 2019 | -12.82% Mar 3, 2023 - Jul 13, 2023 |
| #5 | -13.78% Apr 23, 2015 - May 20, 2015 | -11.86% Jan 22, 2026 - May 11, 2026 |
| #6 | -13.03% Jun 23, 2020 - Oct 7, 2020 | -10.25% Jul 16, 2024 - Aug 23, 2024 |
| #7 | -11.31% Mar 19, 2015 - Apr 13, 2015 | -8.81% Apr 8, 2024 - May 8, 2024 |
| #8 | -7.98% Jul 9, 2026 - Jul 16, 2026 | -8.14% Jun 12, 2026 - Jul 16, 2026 |
| #9 | -6.72% Jun 6, 2018 - Sep 28, 2018 | -7.99% Dec 6, 2024 - Jan 22, 2025 |
| #10 | -6.30% Jan 27, 2015 - Feb 17, 2015 | -6.16% May 15, 2024 - Jul 16, 2024 |
| #11 | -6.29% Jun 22, 2015 - Jul 13, 2015 | -4.16% Oct 28, 2024 - Nov 6, 2024 |
| #12 | -6.19% Dec 22, 2020 - Jan 7, 2021 | -4.11% Jun 4, 2026 - Jun 11, 2026 |
| #13 | -4.88% Oct 13, 2020 - Oct 27, 2020 | -4.02% Aug 30, 2024 - Sep 19, 2024 |
| #14 | -3.81% Jan 14, 2015 - Jan 20, 2015 | -3.49% Feb 15, 2024 - Feb 27, 2024 |
| #15 | -3.39% Oct 27, 2020 - Nov 4, 2020 | -3.30% May 11, 2026 - May 26, 2026 |
Correlation
Correlation between SBIO and ADPV is 0.83 which considered as a strong positive correlation - the stocks tend to move together.
0.83
-101
Dividend Comparison (2017 - 2025)
SBIO vs ADPV dividend yield comparison.
| Year | SBIO | ADPV |
|---|---|---|
| 2025 | 0.00% | 0.70% |
| 2024 | 3.55% | 0.67% |
| 2023 | 0.22% | 0.22% |
| 2022 | 0.00% | 0.25% |
| 2019 | 0.04% | 0.00% |
| 2018 | 2.79% | 0.00% |
| 2017 | 1.77% | 0.00% |
Select Stocks to Compare
Popular: SBIO vs SPYADPV vs SPY
More Comparisons
Compare with similar stocks