USEW vs CANC

Comparison between Cambria US EW ETF (USEW, ETF) and TEMA ONCOLOGY ETF (CANC, ETF).

USEW vs CANC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	USEW(ETF)	CANC(ETF)
Net Assets	$190M	$190M
Expense Ratio	0.30%	0.75%
Max Drawdown	8.25%	97.53%
Sharpe Ratio	1.08	1.94
5Y Beta	0.87	0.74
P/E Ratio	N/A	-28.43
5Y EPS CAGR	N/A	10.35%
Debt to Equity	N/A	66.51%
P/S Ratio	N/A	9.17
P/B Ratio	N/A	7.23

Net Assets

Winner

USEW

$190M

CANC

$190M

Expense Ratio

Winner

USEW

0.30%

CANC

0.75%

Max Drawdown

Winner

USEW

8.25%

CANC

97.53%

Sharpe Ratio

USEW

1.08

Winner

CANC

1.94

5Y Beta

USEW

0.87

Winner

CANC

0.74

P/E Ratio

USEW

N/A

CANC

-28.43

5Y EPS CAGR

USEW

N/A

CANC

10.35%

Debt to Equity

USEW

N/A

CANC

66.51%

P/S Ratio

USEW

N/A

CANC

9.17

P/B Ratio

USEW

N/A

CANC

7.23

USEW vs CANC - Holdings Comparison

USEW and CANC have 11 common holdings. Overlap is 0.93%

USEW's top 25 holdings weight is 48.80%. CANC's top 25 holdings weight is 74.89%.

Rank	USEW	CANC
#1	INVESCO S&P 500® LOW VOLATILITY ETF (SPLV) - 6.64%	REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 6.05%
#2	STATE STREET® SPDR® S&P 500® ETF (SPY) - 4.04%	ELI LILLY AND CO (LLY) - 4.93%
#3	NVIDIA CORP (NVDA) - 3.44%	COGENT BIOSCIENCES INC (COGT) - 4.92%
#4	MICROSOFT CORP (MSFT) - 3.34%	NOVARTIS AG REGISTERED SHARES (n/a) - 4.01%
#5	APPLE INC (AAPL) - 3.01%	ROCHE HOLDING AG ADR (RHHBY) - 3.76%
#6	INVESCO QQQ TRUST (QQQ) - 2.88%	MERCK & CO INC (MRK) - 3.39%
#7	FIDELITY VALUE FACTOR ETF (FVAL) - 2.74%	JOHNSON & JOHNSON (JNJ) - 3.34%
#8	VANGUARD S&P 500 ETF (VOO) - 2.46%	LEGEND BIOTECH CORP ADR (LEGN) - 3.27%
#9	ISHARES RUSSELL 1000 VALUE ETF (IWD) - 1.89%	BRISTOL-MYERS SQUIBB CO (BMY) - 3.25%
#10	n/a (MDYV) - 1.86%	ABBVIE INC (ABBV) - 3.23%
#11	INVESCO S&P 500® EQUAL WEIGHT ETF (RSP) - 1.83%	IMMUNOME INC ORDINARY SHARES (IMNM) - 3.21%
#12	VANGUARD TOTAL STOCK MARKET ETF (VTI) - 1.68%	EXELIXIS INC (EXEL) - 2.86%
#13	ALPHABET INC CLASS C (GOOG) - 1.67%	ASTRAZENECA PLC (AZN:XLON) - 2.72%
#14	INVESCO S&P GLOBAL WATER ETF (CGW) - 1.55%	IDEAYA BIOSCIENCES INC (IDYA) - 2.63%
#15	AMAZON.COM INC (AMZN) - 1.53%	CG ONCOLOGY INC (CGON) - 2.61%
#16	META PLATFORMS INC CLASS A (META) - 1.46%	BRIDGEBIO PHARMA INC (BBIO) - 2.59%
#17	BERKSHIRE HATHAWAY INC CLASS B (BRK-B) - 1.46%	AMGEN INC (AMGN) - 2.53%
#18	BROADCOM INC (AVGO) - 1.37%	GENMAB AS ADR (GMAB) - 2.42%
#19	VANGUARD VALUE ETF (VTV) - 1.25%	CELCUITY INC (CELC) - 2.40%
#20	PROSHARES S&P 500 DIVIDEND ARISTOCRATS (NOBL) - 1.12%	FIRST AMERICAN TREASURY OBLIGS X (FXFXX) - 1.91%
#21	n/a (SHOP) - 0.33%	ERASCA INC (ERAS) - 1.88%
#22	ISHARES CORE S&P MID-CAP ETF (IJH) - 0.32%	BEONE MEDICINES LTD ADR (ONC) - 1.86%
#23	ISHARES MSCI USA MOMENTUM FACTOR ETF (MTUM) - 0.32%	RELAY THERAPEUTICS INC ORDINARY SHARES (RLAY) - 1.78%
#24	ISHARES MSCI USA MIN VOL FACTOR ETF (USMV) - 0.31%	HALOZYME THERAPEUTICS INC (HALO) - 1.68%
#25	AMERICAN EXPRESS CO (AXP) - 0.30%	ENLIVEN THERAPEUTICS INC (ELVN) - 1.66%
Total Holdings	557	60

USEW vs CANC - Historical Returns

Returns include dividend reinvestment.

Period	USEW	CANC
1 month	+0.51%	+6.69%
3 months	+5.02%	+7.60%
6 months	+7.59%	+11.90%
1 year	N/A	+53.94%
5 years(CAGR)	N/A	-7.32%
Max(CAGR)	+17.48%	-7.32%

USEW

+0.51%

Winner

CANC

+6.69%

USEW

+5.02%

Winner

CANC

+7.60%

USEW

+7.59%

Winner

CANC

+11.90%

USEW

N/A

CANC

+53.94%

5Y(CAGR)

USEW

N/A

CANC

-7.32%

Max(CAGR)

Winner

USEW

+17.48%

CANC

-7.32%

USEW vs CANC - Annual Returns (2021 - 2026)

Returns include dividend reinvestment.

Year	USEW	CANC
2026	+9.07%	+19.41%
2025	+0.77%	+42.13%
2024	N/A	-6.11%
2023	N/A	+515.06%
2022	N/A	-85.58%
2021	N/A	-51.82%

USEW vs CANC Drawdown Comparison

The maximum drawdown for USEW was -7.85%, occurring on Mar 30, 2026. Recovery took 54 trading sessions.

The maximum drawdown for CANC was -97.53%, occurring on Apr 5, 2023. This drawdown has not yet recovered.

The current USEW drawdown is -1.63%. The current CANC drawdown is -50.69%.

Rank	USEW	CANC
#1	-7.85% Jan 27, 2026 - Apr 15, 2026	-97.53% Oct 20, 2021 - Apr 5, 2023
#2	-3.00% Jun 4, 2026 - Jun 15, 2026	-16.18% Oct 5, 2021 - Oct 20, 2021
#3	-2.03% Jan 12, 2026 - Jan 27, 2026	N/A
#4	-1.83% Jul 10, 2026 - Jul 20, 2026	N/A
#5	-1.62% May 14, 2026 - May 22, 2026	N/A
#6	-1.45% Jun 15, 2026 - Jun 30, 2026	N/A
#7	-1.25% Dec 24, 2025 - Jan 6, 2026	N/A
#8	-1.02% Jul 6, 2026 - Jul 10, 2026	N/A
#9	-0.79% May 6, 2026 - May 14, 2026	N/A
#10	-0.67% Jan 6, 2026 - Jan 9, 2026	N/A
#11	-0.63% Apr 17, 2026 - Apr 30, 2026	N/A
#12	-0.48% May 1, 2026 - May 5, 2026	N/A
#13	-0.42% Jun 2, 2026 - Jun 4, 2026	N/A
#14	-0.21% Jun 30, 2026 - Jul 6, 2026	N/A
#15	-0.11% May 26, 2026 - May 28, 2026	N/A