SYRE vs HQY

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Healthequity Inc (HQY, Company).

Both SYRE and HQY are from the Healthcare sector.

5-Year PerformanceHQY has outperformed SYRE, delivering a return of +4.6% compared to -10.2%

SYRE vs HQY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	HQY(COMPANY)
Market Cap	$8.05B	$7.98B
Max Drawdown	99.11%	60.65%
Sharpe Ratio	2.92	0.00
5Y Beta	1.76	0.94
Industry	Biotechnology	Health Information Services
P/E Ratio	-41.36	35.10
Forward P/E	N/A	20.28
PEG Ratio	N/A	0.38
5Y EPS CAGR	-2.15%	114.60%
Debt to Equity	0.00%	46.04%
Free Cash Flow Yield	-2.31%	6.11%

Market Cap

Winner

SYRE

$8.05B

HQY

$7.98B

Max Drawdown

SYRE

99.11%

Winner

HQY

60.65%

Sharpe Ratio

Winner

SYRE

2.92

HQY

0.00

5Y Beta

SYRE

1.76

Winner

HQY

0.94

Industry

SYRE

Biotechnology

HQY

Health Information Services

P/E Ratio

Winner

SYRE

-41.36

HQY

35.10

Forward P/E

SYRE

N/A

HQY

20.28

PEG Ratio

SYRE

N/A

HQY

0.38

5Y EPS CAGR

SYRE

-2.15%

Winner

HQY

114.60%

Debt to Equity

Winner

SYRE

0.00%

HQY

46.04%

Free Cash Flow Yield

SYRE

-2.31%

Winner

HQY

6.11%

SYRE vs HQY - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	HQY
1 month	+22.12%	+9.31%
3 months	+47.95%	+13.62%
6 months	+208.46%	+9.35%
1 year	+566.69%	-1.15%
5 years(CAGR)	-10.25%	+4.57%
10 years(CAGR)	-1.01%	+12.23%
Max(CAGR)	-8.15%	+15.15%

Winner

SYRE

+22.12%

HQY

+9.31%

Winner

SYRE

+47.95%

HQY

+13.62%

Winner

SYRE

+208.46%

HQY

+9.35%

Winner

SYRE

+566.69%

HQY

-1.15%

5Y(CAGR)

SYRE

-10.25%

Winner

HQY

+4.57%

10Y(CAGR)

SYRE

-1.01%

Winner

HQY

+12.23%

Max(CAGR)

SYRE

-8.15%

Winner

HQY

+15.15%

SYRE vs HQY - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SYRE	HQY
2026	+233.78%	+4.39%
2025	+37.36%	-5.37%
2024	+8.79%	+45.01%
2023	+104.27%	+9.23%
2022	-90.57%	+31.60%
2021	-44.51%	-35.80%
2020	+1.55%	-3.52%
2019	-4.98%	+25.31%
2018	+39.22%	+28.36%
2017	+18.38%	+16.10%
2016	-55.48%	+62.27%
2015	N/A	+1.50%
2014	N/A	+44.60%

SYRE vs HQY Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for HQY was -60.65%, occurring on Dec 20, 2021. Recovery took 1516 trading sessions.

The current SYRE drawdown is -65.95%. The current HQY drawdown is -16.98%.

Rank	SYRE	HQY
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-60.65% Nov 7, 2018 - Nov 18, 2024
#2	N/A	-54.61% Nov 11, 2015 - Sep 8, 2016
#3	N/A	-36.07% Feb 12, 2025 - Feb 12, 2026
#4	N/A	-26.64% Dec 26, 2014 - Mar 24, 2015
#5	N/A	-25.46% Jun 8, 2017 - Feb 14, 2018
#6	N/A	-20.14% Oct 10, 2016 - Nov 11, 2016
#7	N/A	-19.61% Sep 10, 2014 - Nov 18, 2014
#8	N/A	-19.35% Aug 5, 2015 - Nov 10, 2015
#9	N/A	-18.68% Jan 18, 2017 - Jun 7, 2017
#10	N/A	-17.11% Sep 11, 2018 - Nov 7, 2018
#11	N/A	-12.96% Nov 21, 2024 - Jan 21, 2025
#12	N/A	-10.53% Feb 21, 2018 - Feb 28, 2018
#13	N/A	-10.23% Nov 28, 2014 - Dec 22, 2014
#14	N/A	-10.22% Jul 26, 2018 - Aug 14, 2018
#15	N/A	-10.21% Aug 14, 2014 - Sep 10, 2014