RAL vs SYRE

Comparison between RALSTON PURINA CO (RAL, Company) and Spyre Therapeutics Inc (SYRE, Company).

RAL is from the Technology sector, while SYRE is from the Healthcare sector.

RAL vs SYRE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RAL(COMPANY)	SYRE(COMPANY)
Market Cap	$7.85B	$7.82B
Max Drawdown	31.79%	99.11%
Sharpe Ratio	1.02	2.87
5Y Beta	1.60	1.75
Industry	Electronic Components	Biotechnology
P/E Ratio	-6.38	-40.18
Forward P/E	37.59	N/A
Dividend Yield	0.21%	N/A
5Y EPS CAGR	N/A	-2.15%
Debt to Equity	73.35%	0.00%
Free Cash Flow Yield	3.85%	-2.37%
P/S Ratio	3.70	650.22
P/B Ratio	5.08	17.32

Market Cap

Winner

RAL

$7.85B

SYRE

$7.82B

Max Drawdown

Winner

RAL

31.79%

SYRE

99.11%

Sharpe Ratio

RAL

1.02

Winner

SYRE

2.87

5Y Beta

Winner

RAL

1.60

SYRE

1.75

Industry

RAL

Electronic Components

SYRE

Biotechnology

P/E Ratio

RAL

-6.38

Winner

SYRE

-40.18

Forward P/E

RAL

37.59

SYRE

N/A

Dividend Yield

RAL

0.21%

SYRE

N/A

5Y EPS CAGR

RAL

N/A

SYRE

-2.15%

Debt to Equity

RAL

73.35%

Winner

SYRE

0.00%

Free Cash Flow Yield

Winner

RAL

3.85%

SYRE

-2.37%

P/S Ratio

Winner

RAL

3.70

SYRE

650.22

P/B Ratio

Winner

RAL

5.08

SYRE

17.32

RAL vs SYRE - Historical Returns

Returns include dividend reinvestment.

Period	RAL	SYRE
1 month	+1.60%	+3.03%
3 months	+55.11%	+44.41%
6 months	+31.15%	+212.13%
1 year	+46.81%	+461.43%
5 years(CAGR)	N/A	-9.42%
10 years(CAGR)	N/A	-1.50%
Max(CAGR)	+42.46%	-8.31%

RAL

+1.60%

Winner

SYRE

+3.03%

Winner

RAL

+55.11%

SYRE

+44.41%

RAL

+31.15%

Winner

SYRE

+212.13%

RAL

+46.81%

Winner

SYRE

+461.43%

5Y(CAGR)

RAL

N/A

SYRE

-9.42%

10Y(CAGR)

RAL

N/A

SYRE

-1.50%

Max(CAGR)

Winner

RAL

+42.46%

SYRE

-8.31%

RAL vs SYRE - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	RAL	SYRE
2026	+37.58%	+226.98%
2025	+5.22%	+37.36%
2024	N/A	+8.79%
2023	N/A	+104.27%
2022	N/A	-90.57%
2021	N/A	-44.51%
2020	N/A	+1.55%
2019	N/A	-4.98%
2018	N/A	+39.22%
2017	N/A	+18.38%
2016	N/A	-55.48%

RAL vs SYRE Drawdown Comparison

The maximum drawdown for RAL was -31.79%, occurring on Feb 5, 2026. Recovery took 67 trading sessions.

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The current RAL drawdown is -4.48%. The current SYRE drawdown is -66.64%.

Rank	RAL	SYRE
#1	-31.79% Feb 4, 2026 - May 12, 2026	-99.11% Apr 8, 2016 - Jun 21, 2023
#2	-16.00% Jul 10, 2025 - Nov 28, 2025	N/A
#3	-9.11% Jun 30, 2026 - Jul 16, 2026	N/A
#4	-6.78% Jun 30, 2025 - Jul 9, 2025	N/A
#5	-4.50% May 13, 2026 - May 22, 2026	N/A
#6	-4.40% Dec 11, 2025 - Dec 19, 2025	N/A
#7	-3.97% Jun 3, 2026 - Jun 9, 2026	N/A
#8	-3.78% Jan 15, 2026 - Jan 22, 2026	N/A
#9	-2.60% Dec 19, 2025 - Jan 9, 2026	N/A
#10	-2.41% Jan 22, 2026 - Feb 3, 2026	N/A
#11	-2.24% Jun 15, 2026 - Jun 23, 2026	N/A
#12	-2.12% Jun 9, 2026 - Jun 11, 2026	N/A
#13	-1.86% Jun 25, 2026 - Jun 30, 2026	N/A
#14	-1.66% May 27, 2026 - Jun 3, 2026	N/A
#15	-1.28% Nov 28, 2025 - Dec 3, 2025	N/A