SYRE vs PL

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Planet Labs PBC - Class A (PL, Company).

SYRE is from the Healthcare sector, while PL is from the Industrials sector.

5-Year PerformancePL has outperformed SYRE, delivering a return of +15.7% compared to -9.0%

SYRE vs PL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	PL(COMPANY)
Market Cap	$7.82B	$7.81B
Max Drawdown	99.11%	85.73%
Sharpe Ratio	2.80	1.50
5Y Beta	1.74	2.32
Industry	Biotechnology	Aerospace & Defense
P/E Ratio	-40.18	-31.85
PEG Ratio	N/A	-0.51
5Y EPS CAGR	-2.15%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.37%	0.60%
P/S Ratio	650.22	24.00
P/B Ratio	17.32	18.55

Market Cap

Winner

SYRE

$7.82B

$7.81B

Max Drawdown

SYRE

99.11%

Winner

85.73%

Sharpe Ratio

Winner

SYRE

2.80

1.50

5Y Beta

Winner

SYRE

1.74

2.32

Industry

SYRE

Biotechnology

Aerospace & Defense

P/E Ratio

Winner

SYRE

-40.18

-31.85

PEG Ratio

SYRE

N/A

-0.51

5Y EPS CAGR

SYRE

-2.15%

N/A

Debt to Equity

SYRE

0.00%

Free Cash Flow Yield

SYRE

-2.37%

Winner

0.60%

P/S Ratio

SYRE

650.22

Winner

24.00

P/B Ratio

Winner

SYRE

17.32

18.55

SYRE vs PL - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	PL
1 month	+18.43%	-22.17%
3 months	+46.59%	-42.24%
6 months	+218.81%	-24.02%
1 year	+480.28%	+199.27%
5 years(CAGR)	-9.03%	+15.65%
10 years(CAGR)	-0.98%	N/A
Max(CAGR)	-8.12%	+14.86%

Winner

SYRE

+18.43%

-22.17%

Winner

SYRE

+46.59%

-42.24%

Winner

SYRE

+218.81%

-24.02%

Winner

SYRE

+480.28%

+199.27%

5Y(CAGR)

SYRE

-9.03%

Winner

+15.65%

10Y(CAGR)

SYRE

-0.98%

N/A

Max(CAGR)

SYRE

-8.12%

Winner

+14.86%

SYRE vs PL - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	SYRE	PL
2026	+233.98%	+0.29%
2025	+37.36%	+396.73%
2024	+8.79%	+69.75%
2023	+104.27%	-45.11%
2022	-90.57%	-27.62%
2021	-44.51%	-37.88%
2020	+1.55%	N/A
2019	-4.98%	N/A
2018	+39.22%	N/A
2017	+18.38%	N/A
2016	-55.48%	N/A

SYRE vs PL Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for PL was -85.73%, occurring on Apr 30, 2024. Recovery took 961 trading sessions.

The current SYRE drawdown is -65.93%. The current PL drawdown is -60.18%.

Rank	SYRE	PL
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-85.73% Nov 22, 2021 - Sep 23, 2025
#2	N/A	-60.18% May 28, 2026 - Jul 24, 2026
#3	N/A	-29.01% Jan 16, 2026 - Mar 20, 2026
#4	N/A	-28.83% Oct 7, 2025 - Dec 11, 2025
#5	N/A	-21.15% Mar 25, 2026 - Apr 2, 2026
#6	N/A	-14.57% Apr 16, 2026 - May 11, 2026
#7	N/A	-9.70% Dec 12, 2025 - Dec 19, 2025
#8	N/A	-7.17% Apr 8, 2026 - Apr 16, 2026
#9	N/A	-6.61% Dec 23, 2025 - Jan 5, 2026
#10	N/A	-5.91% Mar 20, 2026 - Mar 25, 2026
#11	N/A	-3.37% May 14, 2026 - May 22, 2026
#12	N/A	-2.77% May 11, 2026 - May 14, 2026
#13	N/A	-2.48% Nov 9, 2021 - Nov 15, 2021
#14	N/A	-2.40% Apr 2, 2026 - Apr 8, 2026
#15	N/A	-2.30% Apr 29, 2021 - Oct 28, 2021