SYRE vs CAE

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Cae Inc (CAE, Company).

SYRE is from the Healthcare sector, while CAE is from the Industrials sector.

5-Year PerformanceCAE has outperformed SYRE, delivering a return of -4.3% compared to -9.4%

SYRE vs CAE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	CAE(COMPANY)
Market Cap	$7.82B	$7.84B
Max Drawdown	99.11%	80.06%
Sharpe Ratio	2.87	-0.43
5Y Beta	1.75	0.97
Industry	Biotechnology	Aerospace & Defense
P/E Ratio	-40.18	34.40
Forward P/E	N/A	27.70
PEG Ratio	N/A	1.83
5Y Dividends CAGR	N/A	3.71%
5Y EPS CAGR	-2.15%	N/A
Debt to Equity	0.00%	60.97%
Free Cash Flow Yield	-2.37%	4.25%
P/S Ratio	650.22	1.63
P/B Ratio	17.32	2.07

Market Cap

SYRE

$7.82B

Winner

CAE

$7.84B

Max Drawdown

SYRE

99.11%

Winner

CAE

80.06%

Sharpe Ratio

Winner

SYRE

2.87

CAE

-0.43

5Y Beta

SYRE

1.75

Winner

CAE

0.97

Industry

SYRE

Biotechnology

CAE

Aerospace & Defense

P/E Ratio

Winner

SYRE

-40.18

CAE

34.40

Forward P/E

SYRE

N/A

CAE

27.70

PEG Ratio

SYRE

N/A

CAE

1.83

5Y Dividends CAGR

SYRE

N/A

CAE

3.71%

5Y EPS CAGR

SYRE

-2.15%

CAE

N/A

Debt to Equity

Winner

SYRE

0.00%

CAE

60.97%

Free Cash Flow Yield

SYRE

-2.37%

Winner

CAE

4.25%

P/S Ratio

SYRE

650.22

Winner

CAE

1.63

P/B Ratio

SYRE

17.32

Winner

CAE

2.07

SYRE vs CAE - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	CAE
1 month	+3.03%	-0.08%
3 months	+44.41%	-2.24%
6 months	+212.13%	-25.17%
1 year	+461.43%	-13.45%
5 years(CAGR)	-9.42%	-4.35%
10 years(CAGR)	-1.50%	+7.41%
Max(CAGR)	-8.31%	+10.20%

Winner

SYRE

+3.03%

CAE

-0.08%

Winner

SYRE

+44.41%

CAE

-2.24%

Winner

SYRE

+212.13%

CAE

-25.17%

Winner

SYRE

+461.43%

CAE

-13.45%

5Y(CAGR)

SYRE

-9.42%

Winner

CAE

-4.35%

10Y(CAGR)

SYRE

-1.50%

Winner

CAE

+7.41%

Max(CAGR)

SYRE

-8.31%

Winner

CAE

+10.20%

SYRE vs CAE - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYRE	CAE
2026	+226.98%	-19.70%
2025	+37.36%	+24.83%
2024	+8.79%	+19.44%
2023	+104.27%	+10.95%
2022	-90.57%	-24.95%
2021	-44.51%	-5.15%
2020	+1.55%	+4.90%
2019	-4.98%	+44.34%
2018	+39.22%	-0.57%
2017	+18.38%	+35.16%
2016	-55.48%	+30.88%
2015	N/A	-11.59%
2014	N/A	+5.25%
2013	N/A	+26.12%
2012	N/A	+4.66%
2011	N/A	-14.27%
2010	N/A	+39.58%
2009	N/A	+19.14%
2008	N/A	-49.60%
2007	N/A	+47.73%
2006	N/A	+27.39%
2005	N/A	+75.51%
2004	N/A	-5.92%
2003	N/A	+36.71%
2002	N/A	-52.78%
2001	N/A	-9.22%
2000	N/A	+135.45%
1999	N/A	+30.10%

SYRE vs CAE Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for CAE was -79.28%, occurring on Mar 28, 2003. Recovery took 1333 trading sessions.

The current SYRE drawdown is -66.64%. The current CAE drawdown is -27.08%.

Rank	SYRE	CAE
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-79.28% Jun 22, 2001 - Oct 12, 2006
#2	N/A	-69.59% Jul 13, 2007 - Jan 21, 2014
#3	N/A	-67.99% Feb 7, 2020 - Apr 9, 2021
#4	N/A	-54.98% Nov 9, 2021 - Sep 30, 2022
#5	N/A	-27.92% Apr 2, 2014 - Jul 29, 2016
#6	N/A	-17.90% Jun 12, 2018 - Jan 30, 2019
#7	N/A	-15.82% Jun 10, 2021 - Nov 5, 2021
#8	N/A	-15.69% Dec 13, 2000 - Mar 9, 2001
#9	N/A	-15.00% Jan 11, 2000 - Feb 7, 2000
#10	N/A	-13.71% Mar 6, 2000 - Jul 17, 2000
#11	N/A	-13.01% Jul 12, 2019 - Jan 8, 2020
#12	N/A	-10.14% Jul 12, 2017 - Oct 13, 2017
#13	N/A	-9.84% Mar 9, 2001 - May 8, 2001
#14	N/A	-9.52% Sep 18, 2000 - Nov 3, 2000
#15	N/A	-8.59% May 17, 2019 - Jul 2, 2019