PTGX vs FR

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and First Industrial Realty Trust Inc (FR, Company).

PTGX is from the Healthcare sector, while FR is from the Real Estate sector.

5-Year PerformancePTGX has outperformed FR, delivering a return of +23.6% compared to +7.7%

PTGX vs FR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	FR(COMPANY)
Market Cap	$8.70B	$8.73B
Max Drawdown	85.79%	96.22%
Sharpe Ratio	1.88	1.73
5Y Beta	0.23	0.71
Industry	Biotechnology	Reit - Industrial
P/E Ratio	-73.61	25.48
Forward P/E	27.86	36.76
PEG Ratio	0.00	0.91
Dividend Yield	N/A	2.79%
5Y Dividends CAGR	N/A	17.56%
5Y EPS CAGR	1.43%	8.87%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-1.36%	5.29%
P/S Ratio	113.99	11.91
P/B Ratio	12.89	3.13

Market Cap

PTGX

$8.70B

Winner

$8.73B

Max Drawdown

Winner

PTGX

85.79%

96.22%

Sharpe Ratio

Winner

PTGX

1.88

1.73

5Y Beta

Winner

PTGX

0.23

0.71

Industry

PTGX

Biotechnology

Reit - Industrial

P/E Ratio

Winner

PTGX

-73.61

25.48

Forward P/E

Winner

PTGX

27.86

36.76

PEG Ratio

Winner

PTGX

0.00

0.91

Dividend Yield

PTGX

N/A

2.79%

5Y Dividends CAGR

PTGX

N/A

17.56%

5Y EPS CAGR

PTGX

1.43%

Winner

8.87%

Debt to Equity

PTGX

0.00%

Free Cash Flow Yield

PTGX

-1.36%

Winner

5.29%

P/S Ratio

PTGX

113.99

Winner

11.91

P/B Ratio

PTGX

12.89

Winner

3.13

PTGX vs FR - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	FR
1 month	+19.32%	+10.21%
3 months	+27.27%	+10.93%
6 months	+61.02%	+16.56%
1 year	+133.09%	+43.92%
5 years(CAGR)	+23.57%	+7.70%
10 years(CAGR)	+27.65%	+12.31%
Max(CAGR)	+27.65%	+8.32%

Winner

PTGX

+19.32%

+10.21%

Winner

PTGX

+27.27%

+10.93%

Winner

PTGX

+61.02%

+16.56%

Winner

PTGX

+133.09%

+43.92%

5Y(CAGR)

Winner

PTGX

+23.57%

+7.70%

10Y(CAGR)

Winner

PTGX

+27.65%

+12.31%

Max(CAGR)

Winner

PTGX

+27.65%

+8.32%

PTGX vs FR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PTGX	FR
2026	+51.43%	+20.58%
2025	+124.06%	+19.72%
2024	+64.82%	-2.60%
2023	+112.71%	+12.50%
2022	-69.11%	-24.00%
2021	+74.49%	+65.38%
2020	+190.91%	+4.89%
2019	+2.32%	+51.44%
2018	-68.18%	-4.73%
2017	-1.79%	+15.40%
2016	+87.95%	+33.59%
2015	N/A	+9.04%
2014	N/A	+21.16%
2013	N/A	+24.15%
2012	N/A	+31.47%
2011	N/A	+7.80%
2010	N/A	+60.44%
2009	N/A	-24.86%
2008	N/A	-74.85%
2007	N/A	-20.53%
2006	N/A	+27.05%
2005	N/A	+2.54%
2004	N/A	+30.89%
2003	N/A	+30.40%
2002	N/A	-2.10%
2001	N/A	+0.54%
2000	N/A	+37.27%
1999	N/A	+15.05%

PTGX vs FR Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for FR was -95.41%, occurring on Mar 3, 2009. Recovery took 3106 trading sessions.

The current PTGX drawdown is -6.27%.

Rank	PTGX	FR
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-95.41% Nov 21, 2006 - Mar 28, 2019
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-41.12% Feb 14, 2020 - Mar 15, 2021
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-35.95% Dec 29, 2021 - Jan 15, 2026
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-25.81% Apr 12, 2002 - Sep 29, 2003
#5	-19.04% Mar 19, 2021 - May 18, 2021	-17.39% Dec 28, 2000 - Feb 20, 2002
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-17.24% Mar 31, 2004 - Aug 24, 2004
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-15.12% Mar 29, 2006 - Aug 22, 2006
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-11.00% Aug 2, 2005 - Nov 18, 2005
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-10.83% Feb 16, 2005 - Jun 17, 2005
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-10.24% Mar 2, 2026 - Apr 17, 2026
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-9.75% Jul 31, 2000 - Nov 21, 2000
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-8.64% Jan 11, 2000 - Apr 13, 2000
#13	-7.78% Jul 7, 2026 - Jul 13, 2026	-8.16% Nov 22, 2005 - Mar 15, 2006
#14	-7.43% Mar 31, 2026 - Apr 15, 2026	-8.05% Dec 22, 2004 - Feb 10, 2005
#15	-7.20% Jun 14, 2021 - Jun 16, 2021	-7.66% Sep 3, 2021 - Oct 14, 2021