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PTGX vs SPY

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformancePTGX has outperformed SPY, delivering a return of +27.5% compared to +13.3%

PTGX vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
PTGX
$9.83B
Winner
SPY
$795B
Expense Ratio
PTGX
N/A
SPY
0.09%
Max Drawdown
PTGX
85.79%
Winner
SPY
56.47%
Sharpe Ratio
Winner
PTGX
2.17
SPY
1.23
5Y Beta
PTGX
N/A
SPY
1.00
Industry
PTGX
Biotechnology
SPY
N/A
P/E Ratio
PTGX
122.81
Winner
SPY
26.08
Forward P/E
PTGX
38.76
Winner
SPY
21.23
PEG Ratio
PTGX
2.71
Winner
SPY
0.37
5Y Dividends CAGR
PTGX
N/A
SPY
6.00%
5Y EPS CAGR
PTGX
N/A
SPY
26.38%
Debt to Equity
Winner
PTGX
0.00%
SPY
45.86%
Free Cash Flow Yield
PTGX
1.33%
SPY
N/A
P/S Ratio
PTGX
35.59
Winner
SPY
3.75
P/B Ratio
PTGX
11.53
Winner
SPY
5.57

PTGX vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
PTGX
+11.66%
SPY
+3.25%
3M
Winner
PTGX
+56.18%
SPY
+4.16%
6M
Winner
PTGX
+89.59%
SPY
+12.42%
1Y
Winner
PTGX
+179.91%
SPY
+20.62%
5Y(CAGR)
Winner
PTGX
+27.52%
SPY
+13.34%
10Y(CAGR)
Winner
PTGX
+29.74%
SPY
+15.21%
Max(CAGR)
Winner
PTGX
+29.62%
SPY
+8.57%

PTGX vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearPTGXSPY
2026+80.48%+12.94%
2025+124.06%+18.00%
2024+64.82%+25.59%
2023+112.71%+26.72%
2022-69.11%-18.64%
2021+74.49%+30.52%
2020+190.91%+17.28%
2019+2.32%+31.09%
2018-68.18%-5.24%
2017-1.79%+20.78%
2016+87.95%+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

PTGX vs SPY Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current PTGX drawdown is -0.81%. The current SPY drawdown is -1.34%.

RankPTGXSPY
#1-85.79%
Sep 1, 2021 - Mar 10, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-82.13%
Dec 5, 2016 - Feb 16, 2021		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-31.58%
Mar 11, 2025 - Aug 27, 2025		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-20.33%
Oct 17, 2016 - Nov 10, 2016		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-19.04%
Mar 19, 2021 - May 18, 2021		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-16.38%
Dec 12, 2025 - Mar 9, 2026		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-15.52%
Oct 10, 2025 - Nov 24, 2025		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-12.77%
Feb 16, 2021 - Mar 2, 2021		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-12.03%
Apr 17, 2026 - Jun 11, 2026		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-11.53%
Aug 19, 2016 - Aug 31, 2016		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-9.62%
Jun 8, 2021 - Jun 11, 2021		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-8.53%
Aug 27, 2025 - Sep 18, 2025		-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-7.78%
Jul 7, 2026 - Jul 17, 2026		-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-7.43%
Mar 31, 2026 - Apr 15, 2026		-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-7.20%
Jun 14, 2021 - Jun 16, 2021		-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between PTGX and SPY is 0.84 which considered as a strong positive correlation - the stocks tend to move together.

0.84
-101

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