PTGX vs DBX

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Dropbox Inc - Class A (DBX, Company).

PTGX is from the Healthcare sector, while DBX is from the Technology sector.

5-Year PerformancePTGX has outperformed DBX, delivering a return of +24.4% compared to +0.4%

PTGX vs DBX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	DBX(COMPANY)
Market Cap	$6.48B	$6.48B
Max Drawdown	85.79%	62.64%
Sharpe Ratio	1.74	-0.11
5Y Beta	0.26	0.78
Industry	Biotechnology	Software - Infrastructure
P/E Ratio	-54.82	14.21
Forward P/E	21.37	9.17
PEG Ratio	0.00	0.38
5Y EPS CAGR	1.43%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-1.82%	15.12%
P/S Ratio	87.39	2.55
P/B Ratio	9.90	29.81

Market Cap

PTGX

$6.48B

Winner

DBX

$6.48B

Max Drawdown

PTGX

85.79%

Winner

DBX

62.64%

Sharpe Ratio

Winner

PTGX

1.74

DBX

-0.11

5Y Beta

Winner

PTGX

0.26

DBX

0.78

Industry

PTGX

Biotechnology

DBX

Software - Infrastructure

P/E Ratio

Winner

PTGX

-54.82

DBX

14.21

Forward P/E

PTGX

21.37

Winner

DBX

9.17

PEG Ratio

Winner

PTGX

0.00

DBX

0.38

5Y EPS CAGR

PTGX

1.43%

DBX

N/A

Debt to Equity

PTGX

0.00%

DBX

0.00%

Free Cash Flow Yield

PTGX

-1.82%

Winner

DBX

15.12%

P/S Ratio

PTGX

87.39

Winner

DBX

2.55

P/B Ratio

Winner

PTGX

9.90

DBX

29.81

PTGX vs DBX - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	DBX
1 month	-3.66%	+10.82%
3 months	+23.26%	+6.95%
6 months	+19.45%	-8.13%
1 year	+122.63%	-4.69%
5 years(CAGR)	+24.38%	+0.39%
10 years(CAGR)	+24.80%	-0.54%
Max(CAGR)	+24.80%	-0.54%

PTGX

-3.66%

Winner

DBX

+10.82%

Winner

PTGX

+23.26%

DBX

+6.95%

Winner

PTGX

+19.45%

DBX

-8.13%

Winner

PTGX

+122.63%

DBX

-4.69%

5Y(CAGR)

Winner

PTGX

+24.38%

DBX

+0.39%

10Y(CAGR)

Winner

PTGX

+24.80%

DBX

-0.54%

Max(CAGR)

Winner

PTGX

+24.80%

DBX

-0.54%

PTGX vs DBX - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	PTGX	DBX
2026	+17.01%	+1.19%
2025	+124.06%	-5.95%
2024	+64.82%	+4.31%
2023	+112.71%	+29.98%
2022	-69.11%	-10.34%
2021	+74.49%	+11.29%
2020	+190.91%	+22.66%
2019	+2.32%	-13.35%
2018	-68.18%	-28.27%
2017	-1.79%	N/A
2016	+87.95%	N/A

PTGX vs DBX Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for DBX was -62.64%, occurring on Mar 12, 2020. This drawdown has not yet recovered.

The current PTGX drawdown is -3.75%. The current DBX drawdown is -35.12%.

Rank	PTGX	DBX
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-62.64% Jun 18, 2018 - Mar 12, 2020
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-13.92% Apr 12, 2018 - Jun 14, 2018
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-4.59% Apr 3, 2018 - Apr 11, 2018
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-3.97% Mar 29, 2018 - Apr 3, 2018
#5	-19.04% Mar 19, 2021 - May 18, 2021	-1.81% Mar 26, 2018 - Mar 28, 2018
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	N/A
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	N/A
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	N/A
#9	-11.53% Aug 19, 2016 - Aug 31, 2016	N/A
#10	-9.62% Jun 8, 2021 - Jun 11, 2021	N/A
#11	-8.53% Aug 27, 2025 - Sep 18, 2025	N/A
#12	-7.43% Mar 31, 2026 - Apr 15, 2026	N/A
#13	-7.20% Jun 14, 2021 - Jun 16, 2021	N/A
#14	-7.18% Apr 17, 2026 - May 1, 2026	N/A
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	N/A