PTGX vs COLB

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Columbia Banking System Inc (COLB, Company).

PTGX is from the Healthcare sector, while COLB is from the Financial Services sector.

5-Year PerformancePTGX has outperformed COLB, delivering a return of +24.8% compared to +2.0%

PTGX vs COLB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	COLB(COMPANY)
Market Cap	$8.88B	$8.87B
Max Drawdown	85.79%	86.81%
Sharpe Ratio	2.09	1.14
5Y Beta	0.24	1.14
Industry	Biotechnology	Banks - Regional
P/E Ratio	110.94	12.81
Forward P/E	30.96	10.26
PEG Ratio	2.44	5.41
Dividend Yield	N/A	4.74%
5Y Dividends CAGR	N/A	10.32%
5Y EPS CAGR	N/A	-2.54%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	1.47%	14.73%
P/S Ratio	117.93	3.54
P/B Ratio	13.40	1.17

Market Cap

Winner

PTGX

$8.88B

COLB

$8.87B

Max Drawdown

Winner

PTGX

85.79%

COLB

86.81%

Sharpe Ratio

Winner

PTGX

2.09

COLB

1.14

5Y Beta

Winner

PTGX

0.24

COLB

1.14

Industry

PTGX

Biotechnology

COLB

Banks - Regional

P/E Ratio

PTGX

110.94

Winner

COLB

12.81

Forward P/E

PTGX

30.96

Winner

COLB

10.26

PEG Ratio

Winner

PTGX

2.44

COLB

5.41

Dividend Yield

PTGX

N/A

COLB

4.74%

5Y Dividends CAGR

PTGX

N/A

COLB

10.32%

5Y EPS CAGR

PTGX

N/A

COLB

-2.54%

Debt to Equity

PTGX

0.00%

COLB

0.00%

Free Cash Flow Yield

PTGX

1.47%

Winner

COLB

14.73%

P/S Ratio

PTGX

117.93

Winner

COLB

3.54

P/B Ratio

PTGX

13.40

Winner

COLB

1.17

PTGX vs COLB - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	COLB
1 month	+3.56%	-2.74%
3 months	+47.57%	+7.00%
6 months	+72.65%	-0.09%
1 year	+186.24%	+39.14%
5 years(CAGR)	+24.83%	+2.02%
10 years(CAGR)	+28.74%	+3.96%
Max(CAGR)	+28.74%	+6.66%

Winner

PTGX

+3.56%

COLB

-2.74%

Winner

PTGX

+47.57%

COLB

+7.00%

Winner

PTGX

+72.65%

COLB

-0.09%

Winner

PTGX

+186.24%

COLB

+39.14%

5Y(CAGR)

Winner

PTGX

+24.83%

COLB

+2.02%

10Y(CAGR)

Winner

PTGX

+28.74%

COLB

+3.96%

Max(CAGR)

Winner

PTGX

+28.74%

COLB

+6.66%

PTGX vs COLB - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PTGX	COLB
2026	+67.32%	+13.66%
2025	+124.06%	+9.97%
2024	+64.82%	+8.38%
2023	+112.71%	-3.10%
2022	-69.11%	-6.25%
2021	+74.49%	-4.16%
2020	+190.91%	-8.19%
2019	+2.32%	+13.95%
2018	-68.18%	-14.37%
2017	-1.79%	-0.31%
2016	+87.95%	+47.89%
2015	N/A	+23.24%
2014	N/A	+4.20%
2013	N/A	+49.96%
2012	N/A	-5.65%
2011	N/A	-9.53%
2010	N/A	+27.06%
2009	N/A	+37.91%
2008	N/A	-57.72%
2007	N/A	-12.36%
2006	N/A	+21.87%
2005	N/A	+17.16%
2004	N/A	+21.34%
2003	N/A	+69.18%
2002	N/A	-0.27%
2001	N/A	-4.30%
2000	N/A	+20.25%
1999	N/A	-3.67%

PTGX vs COLB Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for COLB was -85.93%, occurring on Mar 9, 2009. Recovery took 2236 trading sessions.

The current PTGX drawdown is -0.21%. The current COLB drawdown is -19.08%.

Rank	PTGX	COLB
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-85.93% Jun 30, 2006 - May 20, 2015
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-60.76% Mar 12, 2021 - May 12, 2023
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-53.60% Dec 4, 2017 - Feb 8, 2021
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-36.63% Nov 30, 1999 - Mar 17, 2003
#5	-19.04% Mar 19, 2021 - May 18, 2021	-24.14% Nov 11, 2015 - Nov 9, 2016
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-23.02% Mar 31, 2004 - Dec 28, 2004
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-19.21% Dec 27, 2016 - Nov 2, 2017
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-15.73% Jul 28, 2005 - Oct 31, 2005
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-14.85% Dec 28, 2004 - Jul 20, 2005
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-14.11% Aug 17, 2015 - Oct 28, 2015
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-8.58% Apr 19, 2006 - Jun 29, 2006
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-8.02% Feb 24, 2021 - Mar 8, 2021
#13	-7.78% Jul 7, 2026 - Jul 17, 2026	-7.94% Jul 14, 2003 - Sep 19, 2003
#14	-7.43% Mar 31, 2026 - Apr 15, 2026	-7.16% Sep 22, 2003 - Oct 7, 2003
#15	-7.20% Jun 14, 2021 - Jun 16, 2021	-6.86% Oct 14, 2003 - Nov 5, 2003