PTGX vs BRKR

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Bruker Corp (BRKR, Company).

Both PTGX and BRKR are from the Healthcare sector.

5-Year PerformancePTGX has outperformed BRKR, delivering a return of +27.4% compared to -8.6%

PTGX vs BRKR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	BRKR(COMPANY)
Market Cap	$6.67B	$6.67B
Max Drawdown	85.79%	94.83%
Sharpe Ratio	1.87	0.49
5Y Beta	0.26	1.22
Industry	Biotechnology	Medical Devices
P/E Ratio	-56.45	-326.87
Forward P/E	23.75	15.22
PEG Ratio	0.00	1.52
Dividend Yield	N/A	0.45%
5Y Dividends CAGR	N/A	4.56%
5Y EPS CAGR	1.43%	N/A
Debt to Equity	0.00%	67.41%
Free Cash Flow Yield	-1.77%	0.77%
P/S Ratio	90.08	1.93
P/B Ratio	9.75	2.75

Market Cap

PTGX

$6.67B

Winner

BRKR

$6.67B

Max Drawdown

Winner

PTGX

85.79%

BRKR

94.83%

Sharpe Ratio

Winner

PTGX

1.87

BRKR

0.49

5Y Beta

Winner

PTGX

0.26

BRKR

1.22

Industry

PTGX

Biotechnology

BRKR

Medical Devices

P/E Ratio

PTGX

-56.45

Winner

BRKR

-326.87

Forward P/E

PTGX

23.75

Winner

BRKR

15.22

PEG Ratio

Winner

PTGX

0.00

BRKR

1.52

Dividend Yield

PTGX

N/A

BRKR

0.45%

5Y Dividends CAGR

PTGX

N/A

BRKR

4.56%

5Y EPS CAGR

PTGX

1.43%

BRKR

N/A

Debt to Equity

Winner

PTGX

0.00%

BRKR

67.41%

Free Cash Flow Yield

PTGX

-1.77%

Winner

BRKR

0.77%

P/S Ratio

PTGX

90.08

Winner

BRKR

1.93

P/B Ratio

PTGX

9.75

Winner

BRKR

2.75

PTGX vs BRKR - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	BRKR
1 month	-3.09%	+8.61%
3 months	+25.39%	+17.62%
6 months	+20.77%	+3.29%
1 year	+130.08%	+17.49%
5 years(CAGR)	+27.37%	-8.64%
10 years(CAGR)	+24.87%	+5.09%
Max(CAGR)	+24.87%	+2.60%

PTGX

-3.09%

Winner

BRKR

+8.61%

Winner

PTGX

+25.39%

BRKR

+17.62%

Winner

PTGX

+20.77%

BRKR

+3.29%

Winner

PTGX

+130.08%

BRKR

+17.49%

5Y(CAGR)

Winner

PTGX

+27.37%

BRKR

-8.64%

10Y(CAGR)

Winner

PTGX

+24.87%

BRKR

+5.09%

Max(CAGR)

Winner

PTGX

+24.87%

BRKR

+2.60%

PTGX vs BRKR - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	PTGX	BRKR
2026	+17.21%	-10.74%
2025	+124.06%	-19.50%
2024	+64.82%	-18.68%
2023	+112.71%	+6.70%
2022	-69.11%	-15.34%
2021	+74.49%	+57.75%
2020	+190.91%	+5.77%
2019	+2.32%	+74.60%
2018	-68.18%	-13.33%
2017	-1.79%	+59.94%
2016	+87.95%	-9.90%
2015	N/A	+23.64%
2014	N/A	+0.56%
2013	N/A	+23.52%
2012	N/A	+20.84%
2011	N/A	-24.95%
2010	N/A	+36.51%
2009	N/A	+175.34%
2008	N/A	-69.28%
2007	N/A	+83.70%
2006	N/A	+52.02%
2005	N/A	+24.94%
2004	N/A	-22.05%
2003	N/A	-10.26%
2002	N/A	-70.00%
2001	N/A	-20.71%
2000	N/A	+2.17%

PTGX vs BRKR Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for BRKR was -94.83%, occurring on Mar 12, 2003. Recovery took 4734 trading sessions.

The current PTGX drawdown is -3.59%. The current BRKR drawdown is -54.11%.

Rank	PTGX	BRKR
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-94.83% Aug 31, 2000 - Jun 28, 2019
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-68.72% Mar 21, 2024 - Sep 3, 2025
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-46.31% Sep 3, 2021 - Mar 7, 2024
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-41.49% Jan 16, 2020 - Dec 7, 2020
#5	-19.04% Mar 19, 2021 - May 18, 2021	-22.01% Jul 5, 2019 - Nov 27, 2019
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-8.91% Jan 20, 2021 - Feb 16, 2021
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-8.70% Feb 24, 2021 - Mar 31, 2021
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-6.67% Aug 16, 2000 - Aug 21, 2000
#9	-11.53% Aug 19, 2016 - Aug 31, 2016	-5.11% Apr 27, 2021 - Jun 8, 2021
#10	-9.62% Jun 8, 2021 - Jun 11, 2021	-4.64% Nov 27, 2019 - Dec 20, 2019
#11	-8.53% Aug 27, 2025 - Sep 18, 2025	-4.63% Jun 15, 2021 - Jun 28, 2021
#12	-7.43% Mar 31, 2026 - Apr 15, 2026	-4.51% Aug 22, 2000 - Aug 24, 2000
#13	-7.20% Jun 14, 2021 - Jun 16, 2021	-3.94% Aug 9, 2000 - Aug 16, 2000
#14	-7.18% Apr 17, 2026 - May 1, 2026	-3.91% Dec 18, 2020 - Jan 6, 2021
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	-3.26% Feb 16, 2021 - Feb 24, 2021