PTGX vs THG

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Hanover Insurance Group Inc (THG, Company).

PTGX is from the Healthcare sector, while THG is from the Financial Services sector.

5-Year PerformancePTGX has outperformed THG, delivering a return of +27.4% compared to +8.9%

PTGX vs THG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	THG(COMPANY)
Market Cap	$6.67B	$6.66B
Max Drawdown	85.79%	90.12%
Sharpe Ratio	1.87	0.89
5Y Beta	0.26	0.38
Industry	Biotechnology	Insurance - Property & Casualty
P/E Ratio	-56.45	10.38
Forward P/E	23.75	10.74
PEG Ratio	0.00	0.07
Dividend Yield	N/A	1.93%
5Y Dividends CAGR	N/A	11.24%
5Y EPS CAGR	1.43%	13.85%
Debt to Equity	0.00%	23.63%
Free Cash Flow Yield	-1.77%	18.74%
P/S Ratio	90.08	0.99
P/B Ratio	9.75	1.85

Market Cap

Winner

PTGX

$6.67B

THG

$6.66B

Max Drawdown

Winner

PTGX

85.79%

THG

90.12%

Sharpe Ratio

Winner

PTGX

1.87

THG

0.89

5Y Beta

Winner

PTGX

0.26

THG

0.38

Industry

PTGX

Biotechnology

THG

Insurance - Property & Casualty

P/E Ratio

Winner

PTGX

-56.45

THG

10.38

Forward P/E

PTGX

23.75

Winner

THG

10.74

PEG Ratio

Winner

PTGX

0.00

THG

0.07

Dividend Yield

PTGX

N/A

THG

1.93%

5Y Dividends CAGR

PTGX

N/A

THG

11.24%

5Y EPS CAGR

PTGX

1.43%

Winner

THG

13.85%

Debt to Equity

Winner

PTGX

0.00%

THG

23.63%

Free Cash Flow Yield

PTGX

-1.77%

Winner

THG

18.74%

P/S Ratio

PTGX

90.08

Winner

THG

0.99

P/B Ratio

PTGX

9.75

Winner

THG

1.85

PTGX vs THG - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	THG
1 month	-3.09%	+9.87%
3 months	+25.39%	+13.92%
6 months	+20.77%	+8.49%
1 year	+130.08%	+19.77%
5 years(CAGR)	+27.37%	+8.90%
10 years(CAGR)	+24.87%	+11.51%
Max(CAGR)	+24.87%	+7.03%

PTGX

-3.09%

Winner

THG

+9.87%

Winner

PTGX

+25.39%

THG

+13.92%

Winner

PTGX

+20.77%

THG

+8.49%

Winner

PTGX

+130.08%

THG

+19.77%

5Y(CAGR)

Winner

PTGX

+27.37%

THG

+8.90%

10Y(CAGR)

Winner

PTGX

+24.87%

THG

+11.51%

Max(CAGR)

Winner

PTGX

+24.87%

THG

+7.03%

PTGX vs THG - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PTGX	THG
2026	+17.21%	+9.30%
2025	+124.06%	+22.40%
2024	+64.82%	+29.01%
2023	+112.71%	-8.17%
2022	-69.11%	+5.29%
2021	+74.49%	+16.88%
2020	+190.91%	-12.07%
2019	+2.32%	+28.32%
2018	-68.18%	+11.54%
2017	-1.79%	+21.12%
2016	+87.95%	+16.52%
2015	N/A	+17.70%
2014	N/A	+24.30%
2013	N/A	+56.55%
2012	N/A	+13.94%
2011	N/A	-23.17%
2010	N/A	+7.08%
2009	N/A	+5.78%
2008	N/A	-3.40%
2007	N/A	-5.87%
2006	N/A	+14.26%
2005	N/A	+29.10%
2004	N/A	+6.45%
2003	N/A	+204.96%
2002	N/A	-76.57%
2001	N/A	-33.33%
2000	N/A	+36.05%
1999	N/A	+1.24%

PTGX vs THG Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for THG was -89.84%, occurring on Oct 9, 2002. Recovery took 3234 trading sessions.

The current PTGX drawdown is -3.59%.

Rank	PTGX	THG
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-89.84% Dec 29, 2000 - Nov 8, 2013
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-40.84% Nov 8, 1999 - May 24, 2000
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-40.05% Feb 4, 2020 - Apr 27, 2021
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-30.38% Apr 20, 2022 - Aug 30, 2024
#5	-19.04% Mar 19, 2021 - May 18, 2021	-18.50% Aug 21, 2018 - May 10, 2019
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-17.77% Apr 1, 2016 - Dec 8, 2016
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-14.04% Aug 27, 2021 - Feb 3, 2022
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-13.98% Apr 2, 2025 - May 30, 2025
#9	-11.53% Aug 19, 2016 - Aug 31, 2016	-13.34% Jan 10, 2014 - Mar 31, 2014
#10	-9.62% Jun 8, 2021 - Jun 11, 2021	-12.87% May 24, 2000 - Jul 27, 2000
#11	-8.53% Aug 27, 2025 - Sep 18, 2025	-11.94% Oct 3, 2000 - Dec 7, 2000
#12	-7.43% Mar 31, 2026 - Apr 15, 2026	-11.73% Mar 15, 2017 - Jul 20, 2017
#13	-7.20% Jun 14, 2021 - Jun 16, 2021	-11.07% Aug 16, 2017 - Oct 10, 2017
#14	-7.18% Apr 17, 2026 - May 1, 2026	-10.68% Nov 11, 2015 - Mar 11, 2016
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	-10.32% Nov 29, 2024 - Feb 6, 2025