NPO vs PTGX

Comparison between EnPro Industries Inc (NPO, Company) and Protagonist Therapeutics Inc (PTGX, Company).

NPO is from the Industrials sector, while PTGX is from the Healthcare sector.

5-Year PerformanceNPO has outperformed PTGX, delivering a return of +28.2% compared to +24.4%

NPO vs PTGX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NPO(COMPANY)	PTGX(COMPANY)
Market Cap	$6.44B	$6.48B
Max Drawdown	73.26%	85.79%
Sharpe Ratio	1.53	1.74
5Y Beta	1.50	0.26
Industry	Specialty Industrial Machinery	Biotechnology
P/E Ratio	64.36	-54.82
Forward P/E	33.11	21.37
PEG Ratio	1.34	0.00
Dividend Yield	0.42%	N/A
5Y Dividends CAGR	8.24%	N/A
5Y EPS CAGR	6.73%	1.43%
Debt to Equity	38.74%	0.00%
Free Cash Flow Yield	-0.43%	-1.82%
P/S Ratio	5.50	87.39
P/B Ratio	4.04	9.90

Market Cap

NPO

$6.44B

Winner

PTGX

$6.48B

Max Drawdown

Winner

NPO

73.26%

PTGX

85.79%

Sharpe Ratio

NPO

1.53

Winner

PTGX

1.74

5Y Beta

NPO

1.50

Winner

PTGX

0.26

Industry

NPO

Specialty Industrial Machinery

PTGX

Biotechnology

P/E Ratio

NPO

64.36

Winner

PTGX

-54.82

Forward P/E

NPO

33.11

Winner

PTGX

21.37

PEG Ratio

NPO

1.34

Winner

PTGX

0.00

Dividend Yield

NPO

0.42%

PTGX

N/A

5Y Dividends CAGR

NPO

8.24%

PTGX

N/A

5Y EPS CAGR

Winner

NPO

6.73%

PTGX

1.43%

Debt to Equity

NPO

38.74%

Winner

PTGX

0.00%

Free Cash Flow Yield

Winner

NPO

-0.43%

PTGX

-1.82%

P/S Ratio

Winner

NPO

5.50

PTGX

87.39

P/B Ratio

Winner

NPO

4.04

PTGX

9.90

NPO vs PTGX - Historical Returns

Returns include dividend reinvestment.

Period	NPO	PTGX
1 month	+7.40%	-3.66%
3 months	+10.44%	+23.26%
6 months	+40.79%	+19.45%
1 year	+68.85%	+122.63%
5 years(CAGR)	+28.16%	+24.38%
10 years(CAGR)	+21.64%	+24.80%
Max(CAGR)	+16.76%	+24.80%

Winner

NPO

+7.40%

PTGX

-3.66%

NPO

+10.44%

Winner

PTGX

+23.26%

Winner

NPO

+40.79%

PTGX

+19.45%

NPO

+68.85%

Winner

PTGX

+122.63%

5Y(CAGR)

Winner

NPO

+28.16%

PTGX

+24.38%

10Y(CAGR)

NPO

+21.64%

Winner

PTGX

+24.80%

Max(CAGR)

NPO

+16.76%

Winner

PTGX

+24.80%

NPO vs PTGX - Annual Returns (2002 - 2026)

Returns include dividend reinvestment.

Year	NPO	PTGX
2026	+38.33%	+17.01%
2025	+27.37%	+124.06%
2024	+11.54%	+64.82%
2023	+45.70%	+112.71%
2022	+0.14%	-69.11%
2021	+51.83%	+74.49%
2020	+13.62%	+190.91%
2019	+10.28%	+2.32%
2018	-34.84%	-68.18%
2017	+39.41%	-1.79%
2016	+59.13%	+87.95%
2015	-28.56%	N/A
2014	+10.22%	N/A
2013	+37.69%	N/A
2012	+20.86%	N/A
2011	-21.70%	N/A
2010	+51.79%	N/A
2009	+20.59%	N/A
2008	-29.56%	N/A
2007	-6.87%	N/A
2006	+22.68%	N/A
2005	-7.55%	N/A
2004	+101.98%	N/A
2003	+251.39%	N/A
2002	-52.66%	N/A

NPO vs PTGX Drawdown Comparison

The maximum drawdown for NPO was -73.26%, occurring on Oct 14, 2002. Recovery took 239 trading sessions.

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The current NPO drawdown is -6.32%. The current PTGX drawdown is -3.75%.

Rank	NPO	PTGX
#1	-73.26% May 28, 2002 - May 8, 2003	-85.79% Sep 1, 2021 - Mar 10, 2025
#2	-69.88% Jul 12, 2007 - Jun 28, 2011	-82.13% Dec 5, 2016 - Feb 16, 2021
#3	-65.76% Dec 27, 2017 - Mar 8, 2021	-31.58% Mar 11, 2025 - Aug 27, 2025
#4	-49.65% Jan 21, 2014 - Jul 10, 2017	-20.33% Oct 17, 2016 - Nov 10, 2016
#5	-44.37% Jul 19, 2011 - Mar 22, 2013	-19.04% Mar 19, 2021 - May 18, 2021
#6	-36.50% Jul 8, 2003 - Dec 16, 2003	-16.38% Dec 12, 2025 - Mar 9, 2026
#7	-33.79% Jan 13, 2022 - Nov 3, 2022	-15.52% Oct 10, 2025 - Nov 24, 2025
#8	-33.72% Feb 19, 2025 - Jul 25, 2025	-12.77% Feb 16, 2021 - Mar 2, 2021
#9	-26.40% Aug 2, 2004 - Nov 3, 2004	-11.53% Aug 19, 2016 - Aug 31, 2016
#10	-25.60% Dec 29, 2004 - Jul 28, 2005	-9.62% Jun 8, 2021 - Jun 11, 2021
#11	-25.41% May 4, 2006 - Feb 20, 2007	-8.53% Aug 27, 2025 - Sep 18, 2025
#12	-24.78% Nov 15, 2022 - Jun 13, 2023	-7.43% Mar 31, 2026 - Apr 15, 2026
#13	-24.68% Aug 31, 2005 - Mar 30, 2006	-7.20% Jun 14, 2021 - Jun 16, 2021
#14	-22.36% Jul 18, 2023 - Dec 14, 2023	-7.18% Apr 17, 2026 - May 1, 2026
#15	-18.74% Jun 8, 2021 - Nov 5, 2021	-6.02% Nov 26, 2025 - Dec 8, 2025