MSA vs PTGX

Comparison between MSA Safety Inc (MSA, Company) and Protagonist Therapeutics Inc (PTGX, Company).

MSA is from the Industrials sector, while PTGX is from the Healthcare sector.

5-Year PerformancePTGX has outperformed MSA, delivering a return of +27.4% compared to +1.5%

MSA vs PTGX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MSA(COMPANY)	PTGX(COMPANY)
Market Cap	$6.68B	$6.67B
Max Drawdown	71.48%	85.79%
Sharpe Ratio	0.36	1.87
5Y Beta	0.80	0.26
Industry	Security & Protection Services	Biotechnology
P/E Ratio	23.13	-56.45
Forward P/E	19.61	23.75
PEG Ratio	10.04	0.00
Dividend Yield	1.22%	N/A
5Y Dividends CAGR	4.25%	N/A
5Y EPS CAGR	20.02%	1.43%
Debt to Equity	45.24%	0.00%
Free Cash Flow Yield	4.63%	-1.77%
P/S Ratio	3.47	90.08
P/B Ratio	4.85	9.75

Market Cap

Winner

MSA

$6.68B

PTGX

$6.67B

Max Drawdown

Winner

MSA

71.48%

PTGX

85.79%

Sharpe Ratio

MSA

0.36

Winner

PTGX

1.87

5Y Beta

MSA

0.80

Winner

PTGX

0.26

Industry

MSA

Security & Protection Services

PTGX

Biotechnology

P/E Ratio

MSA

23.13

Winner

PTGX

-56.45

Forward P/E

Winner

MSA

19.61

PTGX

23.75

PEG Ratio

MSA

10.04

Winner

PTGX

0.00

Dividend Yield

MSA

1.22%

PTGX

N/A

5Y Dividends CAGR

MSA

4.25%

PTGX

N/A

5Y EPS CAGR

Winner

MSA

20.02%

PTGX

1.43%

Debt to Equity

MSA

45.24%

Winner

PTGX

0.00%

Free Cash Flow Yield

Winner

MSA

4.63%

PTGX

-1.77%

P/S Ratio

Winner

MSA

3.47

PTGX

90.08

P/B Ratio

Winner

MSA

4.85

PTGX

9.75

MSA vs PTGX - Historical Returns

Returns include dividend reinvestment.

Period	MSA	PTGX
1 month	+3.55%	-3.09%
3 months	-14.94%	+25.39%
6 months	+10.20%	+20.77%
1 year	+9.32%	+130.08%
5 years(CAGR)	+1.54%	+27.37%
10 years(CAGR)	+15.25%	+24.87%
Max(CAGR)	+15.54%	+24.87%

Winner

MSA

+3.55%

PTGX

-3.09%

MSA

-14.94%

Winner

PTGX

+25.39%

MSA

+10.20%

Winner

PTGX

+20.77%

MSA

+9.32%

Winner

PTGX

+130.08%

5Y(CAGR)

MSA

+1.54%

Winner

PTGX

+27.37%

10Y(CAGR)

MSA

+15.25%

Winner

PTGX

+24.87%

Max(CAGR)

MSA

+15.54%

Winner

PTGX

+24.87%

MSA vs PTGX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MSA	PTGX
2026	+6.16%	+17.21%
2025	-1.68%	+124.06%
2024	-0.19%	+64.82%
2023	+19.28%	+112.71%
2022	-1.31%	-69.11%
2021	+4.45%	+74.49%
2020	+17.61%	+190.91%
2019	+34.89%	+2.32%
2018	+21.47%	-68.18%
2017	+13.96%	-1.79%
2016	+66.79%	+87.95%
2015	-15.40%	N/A
2014	+7.28%	N/A
2013	+20.56%	N/A
2012	+31.32%	N/A
2011	+7.35%	N/A
2010	+19.69%	N/A
2009	+14.11%	N/A
2008	-51.53%	N/A
2007	+41.36%	N/A
2006	+0.89%	N/A
2005	-26.70%	N/A
2004	+90.76%	N/A
2003	+160.78%	N/A
2002	-18.11%	N/A
2001	+67.71%	N/A
2000	+20.00%	N/A
1999	+5.15%	N/A

MSA vs PTGX Drawdown Comparison

The maximum drawdown for MSA was -70.36%, occurring on Mar 9, 2009. Recovery took 1296 trading sessions.

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The current MSA drawdown is -15.19%. The current PTGX drawdown is -3.59%.

Rank	MSA	PTGX
#1	-70.36% Dec 20, 2007 - Feb 14, 2013	-85.79% Sep 1, 2021 - Mar 10, 2025
#2	-45.18% Oct 4, 2001 - Aug 20, 2003	-82.13% Dec 5, 2016 - Feb 16, 2021
#3	-38.39% Feb 13, 2020 - Oct 8, 2020	-31.58% Mar 11, 2025 - Aug 27, 2025
#4	-35.28% Feb 22, 2021 - Jun 27, 2023	-20.33% Oct 17, 2016 - Nov 10, 2016
#5	-34.76% Jul 3, 2014 - Aug 23, 2016	-19.04% Mar 19, 2021 - May 18, 2021
#6	-34.27% Jul 16, 2024 - Feb 11, 2026	-16.38% Dec 12, 2025 - Mar 9, 2026
#7	-33.06% Dec 17, 2004 - Aug 8, 2007	-15.52% Oct 10, 2025 - Nov 24, 2025
#8	-26.47% Jun 13, 2000 - Dec 19, 2000	-12.77% Feb 16, 2021 - Mar 2, 2021
#9	-26.07% Jan 20, 2004 - Apr 5, 2004	-11.53% Aug 19, 2016 - Aug 31, 2016
#10	-21.83% Apr 5, 2004 - Jun 7, 2004	-9.62% Jun 8, 2021 - Jun 11, 2021
#11	-20.67% Feb 12, 2026 - Mar 30, 2026	-8.53% Aug 27, 2025 - Sep 18, 2025
#12	-20.64% Jun 1, 2017 - Nov 28, 2017	-7.43% Mar 31, 2026 - Apr 15, 2026
#13	-20.02% Sep 1, 2023 - Feb 29, 2024	-7.20% Jun 14, 2021 - Jun 16, 2021
#14	-19.78% Nov 16, 2018 - May 2, 2019	-7.18% Apr 17, 2026 - May 1, 2026
#15	-19.65% Aug 8, 2007 - Dec 20, 2007	-6.02% Nov 26, 2025 - Dec 8, 2025