KPTI vs CMT

Comparison between Karyopharm Therapeutics Inc (KPTI, Company) and Core Molding Technologies (CMT, Company).

KPTI is from the Healthcare sector, while CMT is from the Basic Materials sector.

5-Year PerformanceCMT has outperformed KPTI, delivering a return of +11.6% compared to -43.7%

KPTI vs CMT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KPTI(COMPANY)	CMT(COMPANY)
Market Cap	$203M	$204M
Max Drawdown	99.50%	96.25%
Sharpe Ratio	1.19	1.01
5Y Beta	0.85	0.68
Industry	Biotechnology	Specialty Chemicals
P/E Ratio	-0.61	138.14
Forward P/E	N/A	21.79
PEG Ratio	-0.01	N/A
5Y EPS CAGR	-18.43%	-17.77%
Debt to Equity	0.00%	12.18%
Free Cash Flow Yield	-29.07%	-7.57%

Market Cap

KPTI

$203M

Winner

CMT

$204M

Max Drawdown

KPTI

99.50%

Winner

CMT

96.25%

Sharpe Ratio

Winner

KPTI

1.19

CMT

1.01

5Y Beta

KPTI

0.85

Winner

CMT

0.68

Industry

KPTI

Biotechnology

CMT

Specialty Chemicals

P/E Ratio

Winner

KPTI

-0.61

CMT

138.14

Forward P/E

KPTI

N/A

CMT

21.79

PEG Ratio

KPTI

-0.01

CMT

N/A

5Y EPS CAGR

KPTI

-18.43%

Winner

CMT

-17.77%

Debt to Equity

Winner

KPTI

0.00%

CMT

12.18%

Free Cash Flow Yield

KPTI

-29.07%

Winner

CMT

-7.57%

KPTI vs CMT - Historical Returns

Returns include dividend reinvestment.

Period	KPTI	CMT
1 month	+26.33%	+2.32%
3 months	+7.38%	+14.75%
6 months	+41.60%	+13.17%
1 year	+103.15%	+43.20%
5 years(CAGR)	-43.65%	+11.60%
10 years(CAGR)	-22.42%	+6.00%
Max(CAGR)	-22.92%	+10.49%

Winner

KPTI

+26.33%

CMT

+2.32%

KPTI

+7.38%

Winner

CMT

+14.75%

Winner

KPTI

+41.60%

CMT

+13.17%

Winner

KPTI

+103.15%

CMT

+43.20%

5Y(CAGR)

KPTI

-43.65%

Winner

CMT

+11.60%

10Y(CAGR)

KPTI

-22.42%

Winner

CMT

+6.00%

Max(CAGR)

KPTI

-22.92%

Winner

CMT

+10.49%

KPTI vs CMT - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	KPTI	CMT
2026	+25.45%	+22.30%
2025	-39.54%	+28.53%
2024	-24.96%	-7.08%
2023	-73.47%	+41.45%
2022	-52.11%	+52.64%
2021	-62.00%	-36.25%
2020	-17.31%	+326.67%
2019	+100.52%	-57.46%
2018	-5.54%	-65.50%
2017	-0.41%	+31.58%
2016	-30.16%	+39.67%
2015	-65.12%	-7.83%
2014	+62.67%	+4.48%
2013	+42.80%	+102.96%
2012	N/A	-19.66%
2011	N/A	+37.35%
2010	N/A	+100.00%
2009	N/A	-0.35%
2008	N/A	-63.38%
2007	N/A	-24.41%
2006	N/A	+29.37%
2005	N/A	+177.17%
2004	N/A	-6.10%
2003	N/A	+165.45%
2002	N/A	-25.17%
2001	N/A	+67.05%
2000	N/A	-66.67%
1999	N/A	+36.69%

KPTI vs CMT Drawdown Comparison

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The maximum drawdown for CMT was -96.21%, occurring on Apr 8, 2020. Recovery took 2090 trading sessions.

The current KPTI drawdown is -98.72%. The current CMT drawdown is -19.73%.

Rank	KPTI	CMT
#1	-99.50% Jun 13, 2014 - Apr 1, 2025	-96.21% Jun 10, 2015 - Sep 28, 2023
#2	-43.74% Mar 6, 2014 - Jun 13, 2014	-90.74% Jun 7, 2005 - Dec 27, 2013
#3	-10.42% Dec 20, 2013 - Jan 15, 2014	-76.87% Dec 22, 1999 - Aug 25, 2003
#4	-9.08% Jan 31, 2014 - Feb 12, 2014	-55.95% Oct 2, 2023 - Mar 3, 2025
#5	-8.83% Mar 4, 2014 - Mar 6, 2014	-42.96% Mar 31, 2004 - Mar 22, 2005
#6	-5.88% Jan 22, 2014 - Jan 30, 2014	-26.50% Apr 8, 2005 - Apr 28, 2005
#7	-4.87% Feb 27, 2014 - Mar 4, 2014	-22.48% Mar 6, 2014 - Mar 18, 2015
#8	-4.36% Feb 13, 2014 - Feb 20, 2014	-19.19% Oct 10, 2003 - Jan 21, 2004
#9	-3.39% Dec 9, 2013 - Dec 13, 2013	-17.02% Nov 11, 1999 - Dec 2, 1999
#10	-1.60% Nov 29, 2013 - Dec 6, 2013	-16.01% Dec 30, 2013 - Feb 14, 2014
#11	-1.48% Nov 8, 2013 - Nov 29, 2013	-15.07% Jan 23, 2004 - Feb 10, 2004
#12	-0.44% Nov 6, 2013 - Nov 8, 2013	-13.77% Mar 28, 2005 - Apr 6, 2005
#13	N/A	-13.74% May 12, 2005 - May 20, 2005
#14	N/A	-12.89% Dec 2, 1999 - Dec 16, 1999
#15	N/A	-10.86% Nov 2, 1999 - Nov 11, 1999