KPTI vs TPVG

Comparison between Karyopharm Therapeutics Inc (KPTI, Company) and TriplePoint Venture Growth BDC Corp (TPVG, Company).

KPTI is from the Healthcare sector, while TPVG is from the Financial Services sector.

5-Year PerformanceTPVG has outperformed KPTI, delivering a return of -7.5% compared to -43.7%

KPTI vs TPVG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KPTI(COMPANY)	TPVG(COMPANY)
Market Cap	$203M	$203M
Max Drawdown	99.50%	82.98%
Sharpe Ratio	1.19	-0.39
5Y Beta	0.85	0.70
Industry	Biotechnology	Asset Management
P/E Ratio	-0.61	4.74
Forward P/E	N/A	5.89
PEG Ratio	-0.01	0.31
Dividend Yield	N/A	19.30%
5Y Dividends CAGR	N/A	-4.24%
5Y EPS CAGR	-18.43%	N/A
Debt to Equity	0.00%	125.90%
Free Cash Flow Yield	-29.07%	-28.83%

Market Cap

Winner

KPTI

$203M

TPVG

$203M

Max Drawdown

KPTI

99.50%

Winner

TPVG

82.98%

Sharpe Ratio

Winner

KPTI

1.19

TPVG

-0.39

5Y Beta

KPTI

0.85

Winner

TPVG

0.70

Industry

KPTI

Biotechnology

TPVG

Asset Management

P/E Ratio

Winner

KPTI

-0.61

TPVG

4.74

Forward P/E

KPTI

N/A

TPVG

5.89

PEG Ratio

Winner

KPTI

-0.01

TPVG

0.31

Dividend Yield

KPTI

N/A

TPVG

19.30%

5Y Dividends CAGR

KPTI

N/A

TPVG

-4.24%

5Y EPS CAGR

KPTI

-18.43%

TPVG

N/A

Debt to Equity

Winner

KPTI

0.00%

TPVG

125.90%

Free Cash Flow Yield

KPTI

-29.07%

Winner

TPVG

-28.83%

KPTI vs TPVG - Historical Returns

Returns include dividend reinvestment.

Period	KPTI	TPVG
1 month	+26.33%	-9.62%
3 months	+7.38%	+1.24%
6 months	+41.60%	-13.20%
1 year	+103.15%	-12.57%
5 years(CAGR)	-43.65%	-7.45%
10 years(CAGR)	-22.42%	+5.67%
Max(CAGR)	-22.92%	+3.39%

Winner

KPTI

+26.33%

TPVG

-9.62%

Winner

KPTI

+7.38%

TPVG

+1.24%

Winner

KPTI

+41.60%

TPVG

-13.20%

Winner

KPTI

+103.15%

TPVG

-12.57%

5Y(CAGR)

KPTI

-43.65%

Winner

TPVG

-7.45%

10Y(CAGR)

KPTI

-22.42%

Winner

TPVG

+5.67%

Max(CAGR)

KPTI

-22.92%

Winner

TPVG

+3.39%

KPTI vs TPVG - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	KPTI	TPVG
2026	+25.45%	-17.90%
2025	-39.54%	+0.92%
2024	-24.96%	-21.30%
2023	-73.47%	+15.59%
2022	-52.11%	-34.25%
2021	-62.00%	+52.73%
2020	-17.31%	+5.20%
2019	+100.52%	+41.34%
2018	-5.54%	-3.87%
2017	-0.41%	+15.87%
2016	-30.16%	+9.87%
2015	-65.12%	-9.96%
2014	+62.67%	+2.88%
2013	+42.80%	N/A

KPTI vs TPVG Drawdown Comparison

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The maximum drawdown for TPVG was -81.82%, occurring on Mar 18, 2020. Recovery took 346 trading sessions.

The current KPTI drawdown is -98.72%. The current TPVG drawdown is -47.44%.

Rank	KPTI	TPVG
#1	-99.50% Jun 13, 2014 - Apr 1, 2025	-81.82% Sep 23, 2019 - Feb 5, 2021
#2	-43.74% Mar 6, 2014 - Jun 13, 2014	-54.72% Nov 22, 2021 - Mar 27, 2026
#3	-10.42% Dec 20, 2013 - Jan 15, 2014	-35.50% Jun 30, 2014 - Nov 30, 2016
#4	-9.08% Jan 31, 2014 - Feb 12, 2014	-20.61% Sep 28, 2018 - Feb 21, 2019
#5	-8.83% Mar 4, 2014 - Mar 6, 2014	-17.03% Nov 29, 2017 - Jul 18, 2018
#6	-5.88% Jan 22, 2014 - Jan 30, 2014	-12.15% May 5, 2021 - Jun 9, 2021
#7	-4.87% Feb 27, 2014 - Mar 4, 2014	-9.74% Apr 28, 2017 - Aug 25, 2017
#8	-4.36% Feb 13, 2014 - Feb 20, 2014	-9.55% Dec 8, 2016 - Jan 18, 2017
#9	-3.39% Dec 9, 2013 - Dec 13, 2013	-8.70% Apr 1, 2014 - Jun 27, 2014
#10	-1.60% Nov 29, 2013 - Dec 6, 2013	-7.98% Jun 11, 2021 - Sep 23, 2021
#11	-1.48% Nov 8, 2013 - Nov 29, 2013	-7.15% Feb 22, 2019 - Mar 26, 2019
#12	-0.44% Nov 6, 2013 - Nov 8, 2013	-6.74% Aug 6, 2018 - Sep 28, 2018
#13	N/A	-6.06% Aug 28, 2017 - Oct 18, 2017
#14	N/A	-5.79% May 3, 2019 - Jun 20, 2019
#15	N/A	-5.53% Mar 12, 2021 - Apr 5, 2021

Correlation

Correlation between KPTI and TPVG is -0.52 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.52

-101