KPTI vs TBI

Comparison between Karyopharm Therapeutics Inc (KPTI, Company) and TrueBlue Inc (TBI, Company).

KPTI is from the Healthcare sector, while TBI is from the Industrials sector.

5-Year PerformanceTBI has outperformed KPTI, delivering a return of -24.8% compared to -43.7%

KPTI vs TBI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KPTI(COMPANY)	TBI(COMPANY)
Market Cap	$203M	$204M
Max Drawdown	99.50%	89.87%
Sharpe Ratio	1.19	0.24
5Y Beta	0.85	0.89
Industry	Biotechnology	Staffing & Employment Services
P/E Ratio	-0.61	-3.78
Forward P/E	N/A	68.03
PEG Ratio	-0.01	N/A
5Y EPS CAGR	-18.43%	N/A
Debt to Equity	0.00%	28.86%
Free Cash Flow Yield	-29.07%	-29.25%

Market Cap

KPTI

$203M

Winner

TBI

$204M

Max Drawdown

KPTI

99.50%

Winner

TBI

89.87%

Sharpe Ratio

Winner

KPTI

1.19

TBI

0.24

5Y Beta

Winner

KPTI

0.85

TBI

0.89

Industry

KPTI

Biotechnology

TBI

Staffing & Employment Services

P/E Ratio

KPTI

-0.61

Winner

TBI

-3.78

Forward P/E

KPTI

N/A

TBI

68.03

PEG Ratio

KPTI

-0.01

TBI

N/A

5Y EPS CAGR

KPTI

-18.43%

TBI

N/A

Debt to Equity

Winner

KPTI

0.00%

TBI

28.86%

Free Cash Flow Yield

Winner

KPTI

-29.07%

TBI

-29.25%

KPTI vs TBI - Historical Returns

Returns include dividend reinvestment.

Period	KPTI	TBI
1 month	+26.33%	+20.07%
3 months	+7.38%	+89.27%
6 months	+41.60%	+38.43%
1 year	+103.15%	-5.37%
5 years(CAGR)	-43.65%	-24.79%
10 years(CAGR)	-22.42%	-10.06%
Max(CAGR)	-22.92%	-2.05%

Winner

KPTI

+26.33%

TBI

+20.07%

KPTI

+7.38%

Winner

TBI

+89.27%

Winner

KPTI

+41.60%

TBI

+38.43%

Winner

KPTI

+103.15%

TBI

-5.37%

5Y(CAGR)

KPTI

-43.65%

Winner

TBI

-24.79%

10Y(CAGR)

KPTI

-22.42%

Winner

TBI

-10.06%

Max(CAGR)

KPTI

-22.92%

Winner

TBI

-2.05%

KPTI vs TBI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	KPTI	TBI
2026	+25.45%	+52.27%
2025	-39.54%	-41.96%
2024	-24.96%	-45.03%
2023	-73.47%	-22.80%
2022	-52.11%	-30.69%
2021	-62.00%	+50.46%
2020	-17.31%	-22.35%
2019	+100.52%	+9.71%
2018	-5.54%	-18.65%
2017	-0.41%	+10.00%
2016	-30.16%	-0.32%
2015	-65.12%	+19.37%
2014	+62.67%	-13.26%
2013	+42.80%	+55.30%
2012	N/A	+9.60%
2011	N/A	-24.57%
2010	N/A	+16.67%
2009	N/A	+49.90%
2008	N/A	-29.63%
2007	N/A	-21.73%
2006	N/A	-13.70%
2005	N/A	+22.61%
2004	N/A	+25.80%
2003	N/A	+104.05%
2002	N/A	+15.47%
2001	N/A	+63.52%
2000	N/A	-72.25%
1999	N/A	+4.30%

KPTI vs TBI Drawdown Comparison

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The maximum drawdown for TBI was -89.87%, occurring on Mar 27, 2026. This drawdown has not yet recovered.

The current KPTI drawdown is -98.72%. The current TBI drawdown is -79.50%.

Rank	KPTI	TBI
#1	-99.50% Jun 13, 2014 - Apr 1, 2025	-89.87% Oct 25, 2021 - Mar 27, 2026
#2	-43.74% Mar 6, 2014 - Jun 13, 2014	-82.20% Dec 6, 1999 - Jun 16, 2004
#3	-10.42% Dec 20, 2013 - Jan 15, 2014	-78.37% Jul 19, 2007 - Feb 28, 2014
#4	-9.08% Jan 31, 2014 - Feb 12, 2014	-61.50% Jun 22, 2015 - Oct 8, 2021
#5	-8.83% Mar 4, 2014 - Mar 6, 2014	-45.31% Apr 24, 2006 - Jul 19, 2007
#6	-5.88% Jan 22, 2014 - Jan 30, 2014	-35.73% Jul 18, 2014 - Jun 22, 2015
#7	-4.87% Feb 27, 2014 - Mar 4, 2014	-26.22% Jun 25, 2004 - Nov 12, 2004
#8	-4.36% Feb 13, 2014 - Feb 20, 2014	-20.59% Jul 20, 2005 - Apr 19, 2006
#9	-3.39% Dec 9, 2013 - Dec 13, 2013	-16.31% Apr 1, 2014 - Jul 16, 2014
#10	-1.60% Nov 29, 2013 - Dec 6, 2013	-13.24% Mar 30, 2005 - May 18, 2005
#11	-1.48% Nov 8, 2013 - Nov 29, 2013	-10.19% Jan 3, 2005 - Feb 3, 2005
#12	-0.44% Nov 6, 2013 - Nov 8, 2013	-9.94% Nov 16, 1999 - Dec 6, 1999
#13	N/A	-9.06% Nov 3, 1999 - Nov 16, 1999
#14	N/A	-7.23% Mar 7, 2005 - Mar 30, 2005
#15	N/A	-6.98% Feb 16, 2005 - Mar 7, 2005