KPTI vs DYORU

Comparison between Karyopharm Therapeutics Inc (KPTI, Company) and Insight Digital Partners II - Units (1 Ord Cls A & 1/2 War) (DYORU, Company).

KPTI is from the Healthcare sector, while DYORU is from the Financial Services sector.

KPTI vs DYORU - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KPTI(COMPANY)	DYORU(COMPANY)
Market Cap	$202M	$202M
Max Drawdown	99.50%	4.41%
Sharpe Ratio	1.20	-0.38
5Y Beta	0.89	-0.09
Industry	Biotechnology	Shell Companies
P/E Ratio	-0.61	N/A
PEG Ratio	-0.01	N/A
5Y EPS CAGR	-18.43%	N/A
Debt to Equity	0.00%	-527.88%
Free Cash Flow Yield	-29.20%	0.00%
P/S Ratio	1.36	N/A
P/B Ratio	12.05	N/A

Market Cap

Winner

KPTI

$202M

DYORU

$202M

Max Drawdown

KPTI

99.50%

Winner

DYORU

4.41%

Sharpe Ratio

Winner

KPTI

1.20

DYORU

-0.38

5Y Beta

KPTI

0.89

Winner

DYORU

-0.09

Industry

KPTI

Biotechnology

DYORU

Shell Companies

P/E Ratio

KPTI

-0.61

DYORU

N/A

PEG Ratio

KPTI

-0.01

DYORU

N/A

5Y EPS CAGR

KPTI

-18.43%

DYORU

N/A

Debt to Equity

KPTI

0.00%

Winner

DYORU

-527.88%

Free Cash Flow Yield

KPTI

-29.20%

Winner

DYORU

0.00%

P/S Ratio

KPTI

1.36

DYORU

N/A

P/B Ratio

KPTI

12.05

DYORU

N/A

KPTI vs DYORU - Historical Returns

Returns include dividend reinvestment.

Period	KPTI	DYORU
1 month	-3.51%	+0.20%
3 months	+2.95%	+0.30%
6 months	+57.91%	+1.00%
1 year	+113.15%	N/A
5 years(CAGR)	-41.65%	N/A
10 years(CAGR)	-23.93%	N/A
Max(CAGR)	-22.94%	+0.00%

KPTI

-3.51%

Winner

DYORU

+0.20%

Winner

KPTI

+2.95%

DYORU

+0.30%

Winner

KPTI

+57.91%

DYORU

+1.00%

KPTI

+113.15%

DYORU

N/A

5Y(CAGR)

KPTI

-41.65%

DYORU

N/A

10Y(CAGR)

KPTI

-23.93%

DYORU

N/A

Max(CAGR)

KPTI

-22.94%

Winner

DYORU

+0.00%

KPTI vs DYORU - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	KPTI	DYORU
2026	+26.29%	+0.60%
2025	-39.54%	-0.59%
2024	-24.96%	N/A
2023	-73.47%	N/A
2022	-52.11%	N/A
2021	-62.00%	N/A
2020	-17.31%	N/A
2019	+100.52%	N/A
2018	-5.54%	N/A
2017	-0.41%	N/A
2016	-30.16%	N/A
2015	-65.12%	N/A
2014	+62.67%	N/A
2013	+42.80%	N/A

KPTI vs DYORU Drawdown Comparison

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The maximum drawdown for DYORU was -4.41%, occurring on Apr 10, 2026. This drawdown has not yet recovered.

The current KPTI drawdown is -98.72%. The current DYORU drawdown is -3.84%.

Rank	KPTI	DYORU
#1	-99.50% Jun 13, 2014 - Apr 1, 2025	-4.41% Mar 30, 2026 - Apr 10, 2026
#2	-43.74% Mar 6, 2014 - Jun 13, 2014	-1.47% Nov 3, 2025 - Jan 14, 2026
#3	-10.42% Dec 20, 2013 - Jan 15, 2014	-0.88% Jan 14, 2026 - Mar 30, 2026
#4	-9.08% Jan 31, 2014 - Feb 12, 2014	-0.05% Oct 30, 2025 - Nov 3, 2025
#5	-8.83% Mar 4, 2014 - Mar 6, 2014	N/A
#6	-5.88% Jan 22, 2014 - Jan 30, 2014	N/A
#7	-4.87% Feb 27, 2014 - Mar 4, 2014	N/A
#8	-4.36% Feb 13, 2014 - Feb 20, 2014	N/A
#9	-3.39% Dec 9, 2013 - Dec 13, 2013	N/A
#10	-1.60% Nov 29, 2013 - Dec 6, 2013	N/A
#11	-1.48% Nov 8, 2013 - Nov 29, 2013	N/A
#12	-0.44% Nov 6, 2013 - Nov 8, 2013	N/A