IONS vs VICR

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Vicor Corp (VICR, Company).

IONS is from the Healthcare sector, while VICR is from the Technology sector.

5-Year PerformanceVICR has outperformed IONS, delivering a return of +24.2% compared to +15.7%

IONS vs VICR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	VICR(COMPANY)
Market Cap	$13B	$13B
Max Drawdown	91.72%	92.90%
Sharpe Ratio	1.90	2.80
5Y Beta	0.75	2.00
Industry	Biotechnology	Electronic Components
P/E Ratio	-72.93	136.20
Forward P/E	96.15	98.04
PEG Ratio	-1.54	0.21
5Y Dividends CAGR	N/A	-17.40%
5Y EPS CAGR	-21.44%	24.34%
Debt to Equity	88.01%	0.00%
Free Cash Flow Yield	-7.62%	0.69%
P/S Ratio	12.00	29.95
P/B Ratio	25.84	15.17

Market Cap

Winner

IONS

$13B

VICR

$13B

Max Drawdown

Winner

IONS

91.72%

VICR

92.90%

Sharpe Ratio

IONS

1.90

Winner

VICR

2.80

5Y Beta

Winner

IONS

0.75

VICR

2.00

Industry

IONS

Biotechnology

VICR

Electronic Components

P/E Ratio

Winner

IONS

-72.93

VICR

136.20

Forward P/E

Winner

IONS

96.15

VICR

98.04

PEG Ratio

Winner

IONS

-1.54

VICR

0.21

5Y Dividends CAGR

IONS

N/A

VICR

-17.40%

5Y EPS CAGR

IONS

-21.44%

Winner

VICR

24.34%

Debt to Equity

IONS

88.01%

Winner

VICR

0.00%

Free Cash Flow Yield

IONS

-7.62%

Winner

VICR

0.69%

P/S Ratio

Winner

IONS

12.00

VICR

29.95

P/B Ratio

IONS

25.84

Winner

VICR

15.17

IONS vs VICR - Historical Returns

Returns include dividend reinvestment.

Period	IONS	VICR
1 month	+0.97%	+42.49%
3 months	-10.71%	+61.26%
6 months	+2.94%	+193.34%
1 year	+131.18%	+524.17%
5 years(CAGR)	+15.68%	+24.20%
10 years(CAGR)	+8.22%	+39.32%
Max(CAGR)	+7.64%	+9.14%

IONS

+0.97%

Winner

VICR

+42.49%

IONS

-10.71%

Winner

VICR

+61.26%

IONS

+2.94%

Winner

VICR

+193.34%

IONS

+131.18%

Winner

VICR

+524.17%

5Y(CAGR)

IONS

+15.68%

Winner

VICR

+24.20%

10Y(CAGR)

IONS

+8.22%

Winner

VICR

+39.32%

Max(CAGR)

IONS

+7.64%

Winner

VICR

+9.14%

IONS vs VICR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	VICR
2026	-4.97%	+119.47%
2025	+128.05%	+127.29%
2024	-33.88%	+15.10%
2023	+34.62%	-17.15%
2022	+15.86%	-56.65%
2021	-46.41%	+40.74%
2020	-7.14%	+89.17%
2019	+12.35%	+24.45%
2018	+9.77%	+78.68%
2017	+6.25%	+35.71%
2016	-22.45%	+64.85%
2015	+0.58%	-22.91%
2014	+54.85%	-4.87%
2013	+268.21%	+132.18%
2012	+44.00%	-33.74%
2011	-29.93%	-51.35%
2010	-10.20%	+75.80%
2009	-23.22%	+46.46%
2008	-7.80%	-54.55%
2007	+44.10%	+39.64%
2006	+111.81%	-27.59%
2005	-9.66%	+18.49%
2004	-13.36%	+15.68%
2003	-4.97%	+28.35%
2002	-68.69%	-49.04%
2001	+130.55%	-40.00%
2000	+77.49%	-22.85%
1999	-44.34%	+42.41%

IONS vs VICR Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for VICR was -92.26%, occurring on Mar 9, 2009. Recovery took 4446 trading sessions.

The current IONS drawdown is -12.47%. The current VICR drawdown is -8.51%.

Rank	IONS	VICR
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-92.26% Oct 2, 2000 - Jun 6, 2018
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-80.47% Nov 17, 2021 - Jan 22, 2026
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-60.03% Jan 24, 2000 - Sep 21, 2000
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-57.41% Aug 9, 2018 - Jun 3, 2020
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-32.01% Mar 2, 2026 - Apr 17, 2026
#6	-28.35% Jul 12, 2013 - Sep 19, 2013	-26.74% Feb 12, 2021 - Jun 29, 2021
#7	-20.89% Sep 23, 2013 - Nov 27, 2013	-17.60% Sep 2, 2020 - Dec 15, 2020
#8	-19.78% Jan 12, 2015 - Mar 19, 2015	-15.84% Jan 12, 2021 - Feb 12, 2021
#9	-19.45% Feb 6, 2026 - Mar 24, 2026	-15.09% Jun 8, 2018 - Jul 17, 2018
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-13.61% Jan 29, 2026 - Feb 23, 2026
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-11.80% Dec 29, 1999 - Jan 20, 2000
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-11.41% Nov 18, 1999 - Dec 17, 1999
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-9.08% Apr 24, 2026 - May 6, 2026
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-8.51% May 6, 2026 - May 8, 2026
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-8.09% Jan 22, 2026 - Jan 29, 2026