IONS vs NTNX

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Nutanix Inc - Class A (NTNX, Company).

IONS is from the Healthcare sector, while NTNX is from the Technology sector.

5-Year PerformanceIONS has outperformed NTNX, delivering a return of +15.7% compared to +10.0%

IONS vs NTNX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	NTNX(COMPANY)
Market Cap	$13B	$13B
Max Drawdown	91.72%	80.40%
Sharpe Ratio	1.90	-0.93
5Y Beta	0.75	1.20
Industry	Biotechnology	Software - Infrastructure
P/E Ratio	-72.93	47.76
Forward P/E	96.15	20.53
PEG Ratio	-1.54	0.98
5Y EPS CAGR	-21.44%	N/A
Debt to Equity	88.01%	-185.61%
Free Cash Flow Yield	-7.62%	6.12%
P/S Ratio	12.00	4.33
P/B Ratio	25.84	98.74

Market Cap

Winner

IONS

$13B

NTNX

$13B

Max Drawdown

IONS

91.72%

Winner

NTNX

80.40%

Sharpe Ratio

Winner

IONS

1.90

NTNX

-0.93

5Y Beta

Winner

IONS

0.75

NTNX

1.20

Industry

IONS

Biotechnology

NTNX

Software - Infrastructure

P/E Ratio

Winner

IONS

-72.93

NTNX

47.76

Forward P/E

IONS

96.15

Winner

NTNX

20.53

PEG Ratio

Winner

IONS

-1.54

NTNX

0.98

5Y EPS CAGR

IONS

-21.44%

NTNX

N/A

Debt to Equity

IONS

88.01%

Winner

NTNX

-185.61%

Free Cash Flow Yield

IONS

-7.62%

Winner

NTNX

6.12%

P/S Ratio

IONS

12.00

Winner

NTNX

4.33

P/B Ratio

Winner

IONS

25.84

NTNX

98.74

IONS vs NTNX - Historical Returns

Returns include dividend reinvestment.

Period	IONS	NTNX
1 month	+0.97%	+16.72%
3 months	-10.71%	+10.60%
6 months	+2.94%	-33.93%
1 year	+131.18%	-38.19%
5 years(CAGR)	+15.68%	+9.95%
10 years(CAGR)	+8.22%	+2.29%
Max(CAGR)	+7.64%	+2.29%

IONS

+0.97%

Winner

NTNX

+16.72%

IONS

-10.71%

Winner

NTNX

+10.60%

Winner

IONS

+2.94%

NTNX

-33.93%

Winner

IONS

+131.18%

NTNX

-38.19%

5Y(CAGR)

Winner

IONS

+15.68%

NTNX

+9.95%

10Y(CAGR)

Winner

IONS

+8.22%

NTNX

+2.29%

Max(CAGR)

Winner

IONS

+7.64%

NTNX

+2.29%

IONS vs NTNX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	NTNX
2026	-4.97%	-9.09%
2025	+128.05%	-15.65%
2024	-33.88%	+33.44%
2023	+34.62%	+81.33%
2022	+15.86%	-17.64%
2021	-46.41%	+2.08%
2020	-7.14%	-0.03%
2019	+12.35%	-25.46%
2018	+9.77%	+15.69%
2017	+6.25%	+34.09%
2016	-22.45%	-28.22%
2015	+0.58%	N/A
2014	+54.85%	N/A
2013	+268.21%	N/A
2012	+44.00%	N/A
2011	-29.93%	N/A
2010	-10.20%	N/A
2009	-23.22%	N/A
2008	-7.80%	N/A
2007	+44.10%	N/A
2006	+111.81%	N/A
2005	-9.66%	N/A
2004	-13.36%	N/A
2003	-4.97%	N/A
2002	-68.69%	N/A
2001	+130.55%	N/A
2000	+77.49%	N/A
1999	-44.34%	N/A

IONS vs NTNX Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for NTNX was -80.40%, occurring on Mar 16, 2020. Recovery took 1435 trading sessions.

The current IONS drawdown is -12.47%. The current NTNX drawdown is -44.63%.

Rank	IONS	NTNX
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-80.40% Jun 18, 2018 - Mar 1, 2024
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-67.48% Oct 3, 2016 - Mar 7, 2018
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-58.58% May 19, 2025 - Apr 10, 2026
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-37.30% May 21, 2024 - Feb 27, 2025
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-24.88% Mar 3, 2025 - May 13, 2025
#6	-28.35% Jul 12, 2013 - Sep 19, 2013	-13.36% Mar 14, 2018 - Apr 17, 2018
#7	-20.89% Sep 23, 2013 - Nov 27, 2013	-12.18% May 10, 2018 - Jun 12, 2018
#8	-19.78% Jan 12, 2015 - Mar 19, 2015	-10.96% Apr 5, 2024 - May 8, 2024
#9	-19.45% Feb 6, 2026 - Mar 24, 2026	-10.66% Apr 18, 2018 - May 7, 2018
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-7.17% Mar 8, 2024 - Apr 5, 2024
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-3.06% Mar 4, 2024 - Mar 8, 2024
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-2.94% May 9, 2024 - May 15, 2024
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-2.54% Jun 13, 2018 - Jun 18, 2018
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-2.11% May 13, 2025 - May 16, 2025
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-0.06% May 15, 2024 - May 17, 2024