DNLI vs MCHB

Comparison between Denali Therapeutics Inc (DNLI, Company) and Mechanics Bancorp Class A Common Stock (MCHB, Company).

5-Year PerformanceDNLI has outperformed MCHB, delivering a return of -21.1% compared to -76.0%

DNLI vs MCHB - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	MCHB(COMPANY)
Market Cap	$3.21B	$3.20B
Max Drawdown	87.74%	99.97%
Sharpe Ratio	0.94	-0.37
Industry	Biotechnology	N/A
P/E Ratio	-6.03	11.32
PEG Ratio	-0.94	N/A
Debt to Equity	0.00%	4.61%
Free Cash Flow Yield	-13.16%	6.82%

Market Cap

Winner

DNLI

$3.21B

MCHB

$3.20B

Max Drawdown

Winner

DNLI

87.74%

MCHB

99.97%

Sharpe Ratio

Winner

DNLI

0.94

MCHB

-0.37

Industry

DNLI

Biotechnology

MCHB

N/A

P/E Ratio

Winner

DNLI

-6.03

MCHB

11.32

PEG Ratio

DNLI

-0.94

MCHB

N/A

Debt to Equity

Winner

DNLI

0.00%

MCHB

4.61%

Free Cash Flow Yield

DNLI

-13.16%

Winner

MCHB

6.82%

DNLI vs MCHB - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	MCHB
1 month	+1.35%	-3.92%
3 months	-4.58%	+9.11%
6 months	+4.18%	+2.90%
1 year	+52.99%	-99.95%
5 years(CAGR)	-21.07%	-75.97%
10 years(CAGR)	-0.70%	-50.71%
Max(CAGR)	-0.70%	-36.15%

Winner

DNLI

+1.35%

MCHB

-3.92%

DNLI

-4.58%

Winner

MCHB

+9.11%

Winner

DNLI

+4.18%

MCHB

+2.90%

Winner

DNLI

+52.99%

MCHB

-99.95%

5Y(CAGR)

Winner

DNLI

-21.07%

MCHB

-75.97%

10Y(CAGR)

Winner

DNLI

-0.70%

MCHB

-50.71%

Max(CAGR)

Winner

DNLI

-0.70%

MCHB

-36.15%

DNLI vs MCHB - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	DNLI	MCHB
2026	+24.22%	+5.63%
2025	-20.78%	-99.94%
2024	-4.72%	+16.95%
2023	-22.33%	+7.09%
2022	-41.17%	-1.18%
2021	-37.06%	+46.54%
2020	+411.04%	-32.97%
2019	-9.88%	-0.78%
2018	+28.08%	+5.97%
2017	-27.09%	+7.68%
2016	N/A	-3.45%
2015	N/A	+11.54%
2014	N/A	+100.00%
2013	N/A	+19.82%
2012	N/A	-5.22%

DNLI vs MCHB Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for MCHB was -99.97%, occurring on Sep 2, 2025. This drawdown has not yet recovered.

The current DNLI drawdown is -78.40%. The current MCHB drawdown is -99.96%.

Rank	DNLI	MCHB
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-99.97% Aug 28, 2025 - Sep 2, 2025
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-49.10% Aug 28, 2017 - Apr 1, 2024
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-19.59% Oct 25, 2024 - Apr 1, 2025
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-13.33% Jul 18, 2013 - May 15, 2014
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-8.44% Sep 20, 2012 - Feb 19, 2013
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-6.90% Dec 23, 2015 - Apr 11, 2017
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-5.31% Jun 7, 2017 - Aug 28, 2017
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-3.70% Apr 10, 2013 - Jul 18, 2013
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-3.23% Apr 11, 2017 - Jun 7, 2017
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-2.74% Jul 25, 2012 - Sep 20, 2012
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-2.33% Aug 21, 2014 - Sep 29, 2014
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-1.92% Apr 3, 2024 - Sep 9, 2024
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-1.92% Nov 4, 2014 - Dec 30, 2014
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-1.79% Sep 1, 2015 - Oct 23, 2015
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-1.54% Mar 1, 2013 - Apr 10, 2013