DNLI vs GPK

Comparison between Denali Therapeutics Inc (DNLI, Company) and Graphic Packaging Holding Company (GPK, Company).

DNLI is from the Healthcare sector, while GPK is from the Consumer Cyclical sector.

5-Year PerformanceGPK has outperformed DNLI, delivering a return of -7.7% compared to -21.1%

DNLI vs GPK - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	GPK(COMPANY)
Market Cap	$3.21B	$3.20B
Max Drawdown	87.74%	94.79%
Sharpe Ratio	0.94	-1.57
5Y Beta	N/A	0.64
Industry	Biotechnology	Packaging & Containers
P/E Ratio	-6.03	11.68
Forward P/E	N/A	13.72
PEG Ratio	-0.94	N/A
Dividend Yield	N/A	4.33%
5Y Dividends CAGR	N/A	12.89%
5Y EPS CAGR	N/A	14.72%
Debt to Equity	0.00%	176.53%
Free Cash Flow Yield	-13.16%	28.17%

Market Cap

Winner

DNLI

$3.21B

GPK

$3.20B

Max Drawdown

Winner

DNLI

87.74%

GPK

94.79%

Sharpe Ratio

Winner

DNLI

0.94

GPK

-1.57

5Y Beta

DNLI

N/A

GPK

0.64

Industry

DNLI

Biotechnology

GPK

Packaging & Containers

P/E Ratio

Winner

DNLI

-6.03

GPK

11.68

Forward P/E

DNLI

N/A

GPK

13.72

PEG Ratio

DNLI

-0.94

GPK

N/A

Dividend Yield

DNLI

N/A

GPK

4.33%

5Y Dividends CAGR

DNLI

N/A

GPK

12.89%

5Y EPS CAGR

DNLI

N/A

GPK

14.72%

Debt to Equity

Winner

DNLI

0.00%

GPK

176.53%

Free Cash Flow Yield

DNLI

-13.16%

Winner

GPK

28.17%

DNLI vs GPK - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	GPK
1 month	+1.35%	+12.71%
3 months	-4.58%	-10.53%
6 months	+4.18%	-31.68%
1 year	+52.99%	-51.45%
5 years(CAGR)	-21.07%	-7.70%
10 years(CAGR)	-0.70%	-0.21%
Max(CAGR)	-0.70%	+1.77%

DNLI

+1.35%

Winner

GPK

+12.71%

Winner

DNLI

-4.58%

GPK

-10.53%

Winner

DNLI

+4.18%

GPK

-31.68%

Winner

DNLI

+52.99%

GPK

-51.45%

5Y(CAGR)

DNLI

-21.07%

Winner

GPK

-7.70%

10Y(CAGR)

DNLI

-0.70%

Winner

GPK

-0.21%

Max(CAGR)

DNLI

-0.70%

Winner

GPK

+1.77%

DNLI vs GPK - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	DNLI	GPK
2026	+24.22%	-27.77%
2025	-20.78%	-42.52%
2024	-4.72%	+10.70%
2023	-22.33%	+15.31%
2022	-41.17%	+14.98%
2021	-37.06%	+17.26%
2020	+411.04%	+5.02%
2019	-9.88%	+57.60%
2018	+28.08%	-30.94%
2017	-27.09%	+24.45%
2016	N/A	-1.04%
2015	N/A	-4.14%
2014	N/A	+43.67%
2013	N/A	+46.56%
2012	N/A	+43.88%
2011	N/A	+5.19%
2010	N/A	+5.99%
2009	N/A	+177.60%
2008	N/A	-67.52%
2007	N/A	-16.70%
2006	N/A	+85.84%
2005	N/A	-68.38%
2004	N/A	+73.91%
2003	N/A	-26.98%
2002	N/A	+17.50%
2001	N/A	+251.45%
2000	N/A	-86.73%
1999	N/A	+25.76%

DNLI vs GPK Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for GPK was -94.79%, occurring on Feb 18, 2009. Recovery took 3658 trading sessions.

The current DNLI drawdown is -78.40%. The current GPK drawdown is -63.20%.

Rank	DNLI	GPK
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-94.79% Nov 15, 1999 - Jun 3, 2014
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-69.70% Sep 19, 2024 - Mar 20, 2026
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-37.67% Jan 11, 2018 - Nov 6, 2019
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-36.93% Dec 18, 2019 - Dec 17, 2020
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-30.81% Feb 20, 2015 - Oct 24, 2017
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-24.57% Jun 12, 2023 - Feb 22, 2024
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-21.12% Nov 2, 1999 - Nov 15, 1999
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-16.69% Sep 12, 2022 - Jan 26, 2023
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-15.69% Jun 2, 2022 - Aug 9, 2022
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-14.98% Sep 15, 2014 - Dec 11, 2014
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-14.03% Nov 16, 2021 - Apr 19, 2022
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-13.81% Jan 12, 2021 - Mar 18, 2021
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-13.73% Apr 9, 2024 - Jul 31, 2024
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-11.43% May 6, 2021 - Aug 11, 2021
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-9.84% May 4, 2022 - Jun 2, 2022