CIO vs BCYC

Comparison between CITY OFFICE REIT, INC. (CIO, Company) and Bicycle Therapeutics Plc (BCYC, Company).

CIO is from the Real Estate sector, while BCYC is from the Healthcare sector.

5-Year PerformanceCIO has outperformed BCYC, delivering a return of +0.4% compared to -33.0%

CIO vs BCYC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CIO(COMPANY)	BCYC(COMPANY)
Market Cap	$282M	$281M
Max Drawdown	83.69%	93.41%
Sharpe Ratio	0.95	-1.22
5Y Beta	N/A	1.28
Industry	Reit - Office	Biotechnology
P/E Ratio	-2.32	-1.28
Forward P/E	384.62	N/A
PEG Ratio	-0.00	-0.18
Dividend Yield	4.29%	N/A
5Y Dividends CAGR	-13.03%	N/A
5Y EPS CAGR	N/A	11.06%
Debt to Equity	65.30%	0.00%
Free Cash Flow Yield	16.87%	-82.48%
P/S Ratio	N/A	4.43
P/B Ratio	N/A	0.51

Market Cap

Winner

CIO

$282M

BCYC

$281M

Max Drawdown

Winner

CIO

83.69%

BCYC

93.41%

Sharpe Ratio

Winner

CIO

0.95

BCYC

-1.22

5Y Beta

CIO

N/A

BCYC

1.28

Industry

CIO

Reit - Office

BCYC

Biotechnology

P/E Ratio

Winner

CIO

-2.32

BCYC

-1.28

Forward P/E

CIO

384.62

BCYC

N/A

PEG Ratio

CIO

-0.00

Winner

BCYC

-0.18

Dividend Yield

CIO

4.29%

BCYC

N/A

5Y Dividends CAGR

CIO

-13.03%

BCYC

N/A

5Y EPS CAGR

CIO

N/A

BCYC

11.06%

Debt to Equity

CIO

65.30%

Winner

BCYC

0.00%

Free Cash Flow Yield

Winner

CIO

16.87%

BCYC

-82.48%

P/S Ratio

CIO

N/A

BCYC

4.43

P/B Ratio

CIO

N/A

BCYC

0.51

CIO vs BCYC - Historical Returns

Returns include dividend reinvestment.

Period	CIO	BCYC
1 month	+0.58%	-14.19%
3 months	+0.43%	-19.64%
6 months	+27.71%	-45.64%
1 year	+37.94%	-53.39%
5 years(CAGR)	+0.37%	-32.99%
10 years(CAGR)	+1.63%	N/A
Max(CAGR)	+2.20%	-14.27%

Winner

CIO

+0.58%

BCYC

-14.19%

Winner

CIO

+0.43%

BCYC

-19.64%

Winner

CIO

+27.71%

BCYC

-45.64%

Winner

CIO

+37.94%

BCYC

-53.39%

5Y(CAGR)

Winner

CIO

+0.37%

BCYC

-32.99%

10Y(CAGR)

CIO

+1.63%

BCYC

N/A

Max(CAGR)

Winner

CIO

+2.20%

BCYC

-14.27%

CIO vs BCYC - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	CIO	BCYC
2026	+0.14%	-39.37%
2025	+36.42%	-50.70%
2024	-5.33%	-24.08%
2023	-20.35%	-39.73%
2022	-55.54%	-50.25%
2021	+117.79%	+217.03%
2020	-20.68%	+82.79%
2019	+41.86%	-21.42%
2018	-14.64%	N/A
2017	+4.93%	N/A
2016	+15.61%	N/A
2015	-0.04%	N/A
2014	+8.52%	N/A

CIO vs BCYC Drawdown Comparison

The maximum drawdown for CIO was -80.90%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The maximum drawdown for BCYC was -93.41%, occurring on Jun 10, 2026. This drawdown has not yet recovered.

The current CIO drawdown is -56.00%. The current BCYC drawdown is -93.38%.

Rank	CIO	BCYC
#1	-80.90% Jan 6, 2022 - Oct 27, 2023	-93.41% Nov 15, 2021 - Jun 10, 2026
#2	-52.69% Feb 18, 2020 - Jul 26, 2021	-53.96% Jun 19, 2019 - Feb 14, 2020
#3	-24.56% Oct 5, 2017 - Jul 5, 2018	-41.61% Mar 10, 2020 - May 28, 2020
#4	-21.53% Apr 7, 2015 - Mar 18, 2016	-25.95% Feb 5, 2021 - Apr 1, 2021
#5	-21.53% Aug 28, 2018 - Jun 13, 2019	-20.84% Jul 23, 2021 - Aug 30, 2021
#6	-15.24% Oct 26, 2021 - Dec 22, 2021	-18.83% Feb 26, 2020 - Mar 4, 2020
#7	-13.83% Mar 18, 2016 - Jun 30, 2016	-18.70% Jul 15, 2020 - Sep 16, 2020
#8	-13.15% Aug 1, 2016 - Aug 31, 2017	-16.36% Apr 8, 2021 - Jul 13, 2021
#9	-11.77% Sep 26, 2019 - Jan 21, 2020	-15.98% Jun 8, 2020 - Jul 14, 2020
#10	-8.03% Jun 16, 2014 - Jul 10, 2014	-15.96% Nov 30, 2020 - Jan 14, 2021
#11	-7.34% Oct 14, 2014 - Apr 2, 2015	-15.70% Mar 4, 2020 - Mar 10, 2020
#12	-6.37% Jun 20, 2019 - Jul 30, 2019	-14.32% Jan 19, 2021 - Feb 5, 2021
#13	-5.00% Sep 7, 2021 - Sep 22, 2021	-14.18% May 24, 2019 - Jun 14, 2019
#14	-4.86% Jul 11, 2014 - Aug 27, 2014	-13.83% Oct 14, 2021 - Nov 15, 2021
#15	-4.43% Aug 27, 2014 - Sep 19, 2014	-12.02% Sep 21, 2020 - Nov 17, 2020