BCYC vs ASYS

Comparison between Bicycle Therapeutics Plc (BCYC, Company) and Amtech Systems Inc (ASYS, Company).

BCYC is from the Healthcare sector, while ASYS is from the Technology sector.

5-Year PerformanceASYS has outperformed BCYC, delivering a return of +19.7% compared to -33.0%

BCYC vs ASYS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	BCYC(COMPANY)	ASYS(COMPANY)
Market Cap	$281M	$280M
Max Drawdown	93.41%	90.02%
Sharpe Ratio	-1.22	2.35
5Y Beta	1.28	1.14
Industry	Biotechnology	Semiconductor Equipment & Materials
P/E Ratio	-1.28	113.76
Forward P/E	N/A	23.09
PEG Ratio	-0.18	0.37
5Y EPS CAGR	11.06%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-82.48%	3.47%
P/S Ratio	4.43	4.23
P/B Ratio	0.51	5.76

Market Cap

Winner

BCYC

$281M

ASYS

$280M

Max Drawdown

BCYC

93.41%

Winner

ASYS

90.02%

Sharpe Ratio

BCYC

-1.22

Winner

ASYS

2.35

5Y Beta

BCYC

1.28

Winner

ASYS

1.14

Industry

BCYC

Biotechnology

ASYS

Semiconductor Equipment & Materials

P/E Ratio

Winner

BCYC

-1.28

ASYS

113.76

Forward P/E

BCYC

N/A

ASYS

23.09

PEG Ratio

Winner

BCYC

-0.18

ASYS

0.37

5Y EPS CAGR

BCYC

11.06%

ASYS

N/A

Debt to Equity

BCYC

0.00%

ASYS

0.00%

Free Cash Flow Yield

BCYC

-82.48%

Winner

ASYS

3.47%

P/S Ratio

BCYC

4.43

Winner

ASYS

4.23

P/B Ratio

Winner

BCYC

0.51

ASYS

5.76

BCYC vs ASYS - Historical Returns

Returns include dividend reinvestment.

Period	BCYC	ASYS
1 month	-14.19%	+14.46%
3 months	-19.64%	+87.72%
6 months	-45.64%	+118.49%
1 year	-53.39%	+450.23%
5 years(CAGR)	-32.99%	+19.75%
10 years(CAGR)	N/A	+13.89%
Max(CAGR)	-14.27%	+9.54%

BCYC

-14.19%

Winner

ASYS

+14.46%

BCYC

-19.64%

Winner

ASYS

+87.72%

BCYC

-45.64%

Winner

ASYS

+118.49%

BCYC

-53.39%

Winner

ASYS

+450.23%

5Y(CAGR)

BCYC

-32.99%

Winner

ASYS

+19.75%

10Y(CAGR)

BCYC

N/A

ASYS

+13.89%

Max(CAGR)

BCYC

-14.27%

Winner

ASYS

+9.54%

BCYC vs ASYS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	BCYC	ASYS
2026	-39.37%	+85.25%
2025	-50.70%	+124.11%
2024	-24.08%	+25.87%
2023	-39.73%	-47.37%
2022	-50.25%	-22.21%
2021	+217.03%	+55.35%
2020	+82.79%	-12.12%
2019	-21.42%	+46.72%
2018	N/A	-57.30%
2017	N/A	+142.07%
2016	N/A	-31.45%
2015	N/A	-39.05%
2014	N/A	+44.68%
2013	N/A	+105.31%
2012	N/A	-62.82%
2011	N/A	-67.26%
2010	N/A	+128.01%
2009	N/A	+193.63%
2008	N/A	-71.46%
2007	N/A	+68.48%
2006	N/A	+4.08%
2005	N/A	+89.51%
2004	N/A	-24.32%
2003	N/A	+77.29%
2002	N/A	-51.45%
2001	N/A	-0.39%
2000	N/A	+60.00%
1999	N/A	+135.29%

BCYC vs ASYS Drawdown Comparison

The maximum drawdown for BCYC was -93.41%, occurring on Jun 10, 2026. This drawdown has not yet recovered.

The maximum drawdown for ASYS was -90.02%, occurring on Dec 7, 2012. This drawdown has not yet recovered.

The current BCYC drawdown is -93.38%. The current ASYS drawdown is -17.48%.

Rank	BCYC	ASYS
#1	-93.41% Nov 15, 2021 - Jun 10, 2026	-90.02% Jan 12, 2011 - Dec 7, 2012
#2	-53.96% Jun 19, 2019 - Feb 14, 2020	-89.72% Aug 28, 2000 - Dec 6, 2010
#3	-41.61% Mar 10, 2020 - May 28, 2020	-61.47% Mar 6, 2000 - Aug 17, 2000
#4	-25.95% Feb 5, 2021 - Apr 1, 2021	-20.47% Jan 21, 2000 - Feb 18, 2000
#5	-20.84% Jul 23, 2021 - Aug 30, 2021	-15.79% Nov 4, 1999 - Nov 30, 1999
#6	-18.83% Feb 26, 2020 - Mar 4, 2020	-15.00% Dec 30, 1999 - Jan 19, 2000
#7	-18.70% Jul 15, 2020 - Sep 16, 2020	-14.56% Aug 17, 2000 - Aug 24, 2000
#8	-16.36% Apr 8, 2021 - Jul 13, 2021	-14.16% Mar 1, 2000 - Mar 6, 2000
#9	-15.98% Jun 8, 2020 - Jul 14, 2020	-10.58% Nov 30, 1999 - Dec 13, 1999
#10	-15.96% Nov 30, 2020 - Jan 14, 2021	-9.64% Feb 23, 2000 - Mar 1, 2000
#11	-15.70% Mar 4, 2020 - Mar 10, 2020	-8.74% Dec 28, 2010 - Jan 11, 2011
#12	-14.32% Jan 19, 2021 - Feb 5, 2021	-8.51% Dec 17, 1999 - Dec 29, 1999
#13	-14.18% May 24, 2019 - Jun 14, 2019	-8.11% Dec 10, 2010 - Dec 20, 2010
#14	-13.83% Oct 14, 2021 - Nov 15, 2021	-6.64% Dec 14, 1999 - Dec 16, 1999
#15	-12.02% Sep 21, 2020 - Nov 17, 2020	-4.44% Dec 6, 2010 - Dec 10, 2010