CIO vs PALI

Comparison between CITY OFFICE REIT, INC. (CIO, Company) and Palisade Bio Inc (PALI, Company).

CIO is from the Real Estate sector, while PALI is from the Healthcare sector.

5-Year PerformanceCIO has outperformed PALI, delivering a return of +0.4% compared to -77.7%

CIO vs PALI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CIO(COMPANY)	PALI(COMPANY)
Market Cap	$282M	$281M
Max Drawdown	83.69%	100.00%
Sharpe Ratio	0.95	1.31
5Y Beta	N/A	0.00
Industry	Reit - Office	Biotechnology
P/E Ratio	-2.32	-9.72
Forward P/E	384.62	N/A
PEG Ratio	-0.00	N/A
Dividend Yield	4.29%	N/A
5Y Dividends CAGR	-13.03%	N/A
Debt to Equity	65.30%	0.00%
Free Cash Flow Yield	16.87%	-4.41%
P/S Ratio	N/A	11.78
P/B Ratio	N/A	2.29

Market Cap

Winner

CIO

$282M

PALI

$281M

Max Drawdown

Winner

CIO

83.69%

PALI

100.00%

Sharpe Ratio

CIO

0.95

Winner

PALI

1.31

5Y Beta

CIO

N/A

PALI

0.00

Industry

CIO

Reit - Office

PALI

Biotechnology

P/E Ratio

CIO

-2.32

Winner

PALI

-9.72

Forward P/E

CIO

384.62

PALI

N/A

PEG Ratio

CIO

-0.00

PALI

N/A

Dividend Yield

CIO

4.29%

PALI

N/A

5Y Dividends CAGR

CIO

-13.03%

PALI

N/A

Debt to Equity

CIO

65.30%

Winner

PALI

0.00%

Free Cash Flow Yield

Winner

CIO

16.87%

PALI

-4.41%

P/S Ratio

CIO

N/A

PALI

11.78

P/B Ratio

CIO

N/A

PALI

2.29

CIO vs PALI - Historical Returns

Returns include dividend reinvestment.

Period	CIO	PALI
1 month	+0.58%	-7.65%
3 months	+0.43%	-15.08%
6 months	+27.71%	-6.63%
1 year	+37.94%	+175.69%
5 years(CAGR)	+0.37%	-77.65%
10 years(CAGR)	+1.63%	-70.80%
Max(CAGR)	+2.20%	-51.60%

Winner

CIO

+0.58%

PALI

-7.65%

Winner

CIO

+0.43%

PALI

-15.08%

Winner

CIO

+27.71%

PALI

-6.63%

CIO

+37.94%

Winner

PALI

+175.69%

5Y(CAGR)

Winner

CIO

+0.37%

PALI

-77.65%

10Y(CAGR)

Winner

CIO

+1.63%

PALI

-70.80%

Max(CAGR)

Winner

CIO

+2.20%

PALI

-51.60%

CIO vs PALI - Annual Returns (2006 - 2026)

Returns include dividend reinvestment.

Year	CIO	PALI
2026	+0.14%	-32.40%
2025	+36.42%	+26.34%
2024	-5.33%	-81.00%
2023	-20.35%	-84.55%
2022	-55.54%	-93.11%
2021	+117.79%	-78.96%
2020	-20.68%	-20.00%
2019	+41.86%	-84.99%
2018	-14.64%	-84.58%
2017	+4.93%	-57.46%
2016	+15.61%	-73.46%
2015	-0.04%	-63.35%
2014	+8.52%	-13.92%
2013	N/A	+140.50%
2012	N/A	+9.00%
2011	N/A	-55.53%
2010	N/A	+14.59%
2009	N/A	+7.19%
2008	N/A	-55.00%
2007	N/A	+48.02%
2006	N/A	+50.00%

CIO vs PALI Drawdown Comparison

The maximum drawdown for CIO was -80.90%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The maximum drawdown for PALI was -100.00%, occurring on Sep 10, 2025. This drawdown has not yet recovered.

The current CIO drawdown is -56.00%. The current PALI drawdown is -100.00%.

Rank	CIO	PALI
#1	-80.90% Jan 6, 2022 - Oct 27, 2023	-100.00% Apr 9, 2014 - Sep 10, 2025
#2	-52.69% Feb 18, 2020 - Jul 26, 2021	-88.86% Apr 26, 2007 - Mar 17, 2014
#3	-24.56% Oct 5, 2017 - Jul 5, 2018	-24.62% Jan 10, 2007 - Mar 26, 2007
#4	-21.53% Apr 7, 2015 - Mar 18, 2016	-18.87% Mar 20, 2014 - Apr 9, 2014
#5	-21.53% Aug 28, 2018 - Jun 13, 2019	-16.00% Dec 29, 2006 - Jan 10, 2007
#6	-15.24% Oct 26, 2021 - Dec 22, 2021	-16.00% Dec 21, 2006 - Dec 29, 2006
#7	-13.83% Mar 18, 2016 - Jun 30, 2016	-7.58% Mar 26, 2007 - Apr 13, 2007
#8	-13.15% Aug 1, 2016 - Aug 31, 2017	-5.95% Mar 17, 2014 - Mar 20, 2014
#9	-11.77% Sep 26, 2019 - Jan 21, 2020	-5.63% Apr 18, 2007 - Apr 26, 2007
#10	-8.03% Jun 16, 2014 - Jul 10, 2014	N/A
#11	-7.34% Oct 14, 2014 - Apr 2, 2015	N/A
#12	-6.37% Jun 20, 2019 - Jul 30, 2019	N/A
#13	-5.00% Sep 7, 2021 - Sep 22, 2021	N/A
#14	-4.86% Jul 11, 2014 - Aug 27, 2014	N/A
#15	-4.43% Aug 27, 2014 - Sep 19, 2014	N/A