BRKR vs PTGX

Comparison between Bruker Corp (BRKR, Company) and Protagonist Therapeutics Inc (PTGX, Company).

Both BRKR and PTGX are from the Healthcare sector.

5-Year PerformancePTGX has outperformed BRKR, delivering a return of +27.4% compared to -8.6%

BRKR vs PTGX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	BRKR(COMPANY)	PTGX(COMPANY)
Market Cap	$6.67B	$6.67B
Max Drawdown	94.83%	85.79%
Sharpe Ratio	0.49	1.87
5Y Beta	1.22	0.26
Industry	Medical Devices	Biotechnology
P/E Ratio	-326.87	-56.45
Forward P/E	15.22	23.75
PEG Ratio	1.52	0.00
Dividend Yield	0.45%	N/A
5Y Dividends CAGR	4.56%	N/A
5Y EPS CAGR	N/A	1.43%
Debt to Equity	67.41%	0.00%
Free Cash Flow Yield	0.77%	-1.77%
P/S Ratio	1.93	90.08
P/B Ratio	2.75	9.75

Market Cap

Winner

BRKR

$6.67B

PTGX

$6.67B

Max Drawdown

BRKR

94.83%

Winner

PTGX

85.79%

Sharpe Ratio

BRKR

0.49

Winner

PTGX

1.87

5Y Beta

BRKR

1.22

Winner

PTGX

0.26

Industry

BRKR

Medical Devices

PTGX

Biotechnology

P/E Ratio

Winner

BRKR

-326.87

PTGX

-56.45

Forward P/E

Winner

BRKR

15.22

PTGX

23.75

PEG Ratio

BRKR

1.52

Winner

PTGX

0.00

Dividend Yield

BRKR

0.45%

PTGX

N/A

5Y Dividends CAGR

BRKR

4.56%

PTGX

N/A

5Y EPS CAGR

BRKR

N/A

PTGX

1.43%

Debt to Equity

BRKR

67.41%

Winner

PTGX

0.00%

Free Cash Flow Yield

Winner

BRKR

0.77%

PTGX

-1.77%

P/S Ratio

Winner

BRKR

1.93

PTGX

90.08

P/B Ratio

Winner

BRKR

2.75

PTGX

9.75

BRKR vs PTGX - Historical Returns

Returns include dividend reinvestment.

Period	BRKR	PTGX
1 month	+8.61%	-3.09%
3 months	+17.62%	+25.39%
6 months	+3.29%	+20.77%
1 year	+17.49%	+130.08%
5 years(CAGR)	-8.64%	+27.37%
10 years(CAGR)	+5.09%	+24.87%
Max(CAGR)	+2.60%	+24.87%

Winner

BRKR

+8.61%

PTGX

-3.09%

BRKR

+17.62%

Winner

PTGX

+25.39%

BRKR

+3.29%

Winner

PTGX

+20.77%

BRKR

+17.49%

Winner

PTGX

+130.08%

5Y(CAGR)

BRKR

-8.64%

Winner

PTGX

+27.37%

10Y(CAGR)

BRKR

+5.09%

Winner

PTGX

+24.87%

Max(CAGR)

BRKR

+2.60%

Winner

PTGX

+24.87%

BRKR vs PTGX - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	BRKR	PTGX
2026	-10.74%	+17.21%
2025	-19.50%	+124.06%
2024	-18.68%	+64.82%
2023	+6.70%	+112.71%
2022	-15.34%	-69.11%
2021	+57.75%	+74.49%
2020	+5.77%	+190.91%
2019	+74.60%	+2.32%
2018	-13.33%	-68.18%
2017	+59.94%	-1.79%
2016	-9.90%	+87.95%
2015	+23.64%	N/A
2014	+0.56%	N/A
2013	+23.52%	N/A
2012	+20.84%	N/A
2011	-24.95%	N/A
2010	+36.51%	N/A
2009	+175.34%	N/A
2008	-69.28%	N/A
2007	+83.70%	N/A
2006	+52.02%	N/A
2005	+24.94%	N/A
2004	-22.05%	N/A
2003	-10.26%	N/A
2002	-70.00%	N/A
2001	-20.71%	N/A
2000	+2.17%	N/A

BRKR vs PTGX Drawdown Comparison

The maximum drawdown for BRKR was -94.83%, occurring on Mar 12, 2003. Recovery took 4734 trading sessions.

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The current BRKR drawdown is -54.11%. The current PTGX drawdown is -3.59%.

Rank	BRKR	PTGX
#1	-94.83% Aug 31, 2000 - Jun 28, 2019	-85.79% Sep 1, 2021 - Mar 10, 2025
#2	-68.72% Mar 21, 2024 - Sep 3, 2025	-82.13% Dec 5, 2016 - Feb 16, 2021
#3	-46.31% Sep 3, 2021 - Mar 7, 2024	-31.58% Mar 11, 2025 - Aug 27, 2025
#4	-41.49% Jan 16, 2020 - Dec 7, 2020	-20.33% Oct 17, 2016 - Nov 10, 2016
#5	-22.01% Jul 5, 2019 - Nov 27, 2019	-19.04% Mar 19, 2021 - May 18, 2021
#6	-8.91% Jan 20, 2021 - Feb 16, 2021	-16.38% Dec 12, 2025 - Mar 9, 2026
#7	-8.70% Feb 24, 2021 - Mar 31, 2021	-15.52% Oct 10, 2025 - Nov 24, 2025
#8	-6.67% Aug 16, 2000 - Aug 21, 2000	-12.77% Feb 16, 2021 - Mar 2, 2021
#9	-5.11% Apr 27, 2021 - Jun 8, 2021	-11.53% Aug 19, 2016 - Aug 31, 2016
#10	-4.64% Nov 27, 2019 - Dec 20, 2019	-9.62% Jun 8, 2021 - Jun 11, 2021
#11	-4.63% Jun 15, 2021 - Jun 28, 2021	-8.53% Aug 27, 2025 - Sep 18, 2025
#12	-4.51% Aug 22, 2000 - Aug 24, 2000	-7.43% Mar 31, 2026 - Apr 15, 2026
#13	-3.94% Aug 9, 2000 - Aug 16, 2000	-7.20% Jun 14, 2021 - Jun 16, 2021
#14	-3.91% Dec 18, 2020 - Jan 6, 2021	-7.18% Apr 17, 2026 - May 1, 2026
#15	-3.26% Feb 16, 2021 - Feb 24, 2021	-6.02% Nov 26, 2025 - Dec 8, 2025