ANTA vs SPRO

Comparison between Antalpha Platform Holding Company (ANTA, Company) and Spero Therapeutics Inc (SPRO, Company).

ANTA is from the Financial Services sector, while SPRO is from the Healthcare sector.

ANTA vs SPRO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ANTA(COMPANY)	SPRO(COMPANY)
Market Cap	$147M	$147M
Max Drawdown	60.62%	97.46%
Sharpe Ratio	-0.54	0.09
5Y Beta	1.40	0.60
Industry	Credit Services	Biotechnology
P/E Ratio	6.00	9.31
Forward P/E	35.46	N/A
PEG Ratio	0.02	0.00
5Y Dividends CAGR	N/A	30.26%
Debt to Equity	13.20%	0.00%
Free Cash Flow Yield	-2.88%	4.93%
P/S Ratio	1.83	2.42
P/B Ratio	1.29	2.81

Market Cap

ANTA

$147M

Winner

SPRO

$147M

Max Drawdown

Winner

ANTA

60.62%

SPRO

97.46%

Sharpe Ratio

ANTA

-0.54

Winner

SPRO

0.09

5Y Beta

ANTA

1.40

Winner

SPRO

0.60

Industry

ANTA

Credit Services

SPRO

Biotechnology

P/E Ratio

Winner

ANTA

6.00

SPRO

9.31

Forward P/E

ANTA

35.46

SPRO

N/A

PEG Ratio

ANTA

0.02

Winner

SPRO

0.00

5Y Dividends CAGR

ANTA

N/A

SPRO

30.26%

Debt to Equity

ANTA

13.20%

Winner

SPRO

0.00%

Free Cash Flow Yield

ANTA

-2.88%

Winner

SPRO

4.93%

P/S Ratio

Winner

ANTA

1.83

SPRO

2.42

P/B Ratio

Winner

ANTA

1.29

SPRO

2.81

ANTA vs SPRO - Historical Returns

Returns include dividend reinvestment.

Period	ANTA	SPRO
1 month	-21.74%	+12.20%
3 months	-11.63%	+10.04%
6 months	-32.35%	+22.84%
1 year	-44.84%	-1.38%
5 years(CAGR)	N/A	-28.65%
10 years(CAGR)	N/A	-2.10%
Max(CAGR)	-43.98%	-0.31%

ANTA

-21.74%

Winner

SPRO

+12.20%

ANTA

-11.63%

Winner

SPRO

+10.04%

ANTA

-32.35%

Winner

SPRO

+22.84%

ANTA

-44.84%

Winner

SPRO

-1.38%

5Y(CAGR)

ANTA

N/A

SPRO

-28.65%

10Y(CAGR)

ANTA

N/A

SPRO

-2.10%

Max(CAGR)

ANTA

-43.98%

Winner

SPRO

-0.31%

ANTA vs SPRO - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	ANTA	SPRO
2026	-25.08%	+21.28%
2025	-30.55%	+115.74%
2024	N/A	-32.24%
2023	N/A	-15.52%
2022	N/A	-88.58%
2021	N/A	-10.71%
2020	N/A	+96.45%
2019	N/A	+53.59%
2018	N/A	-49.34%
2017	N/A	+2.17%
2015	N/A	+125.03%
2014	N/A	-36.85%
2013	N/A	+87.73%
2012	N/A	-15.94%
2011	N/A	-18.88%
2010	N/A	-29.17%
2009	N/A	+37.55%
2008	N/A	-59.66%
2007	N/A	+44.06%
2006	N/A	+26.56%
2005	N/A	-15.34%
2004	N/A	+7.04%

ANTA vs SPRO Drawdown Comparison

The maximum drawdown for ANTA was -60.62%, occurring on Jun 8, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPRO was -97.46%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current ANTA drawdown is -58.24%. The current SPRO drawdown is -87.09%.

Rank	ANTA	SPRO
#1	-60.62% May 14, 2025 - Jun 8, 2026	-97.46% Dec 28, 2020 - Apr 8, 2025
#2	N/A	-85.13% Jul 17, 2007 - Nov 2, 2017
#3	N/A	-70.48% Apr 12, 2018 - Dec 8, 2020
#4	N/A	-42.56% May 17, 2005 - Feb 16, 2007
#5	N/A	-32.47% Nov 13, 2017 - Apr 9, 2018
#6	N/A	-18.79% Mar 12, 2007 - Jun 19, 2007
#7	N/A	-9.16% Jun 25, 2007 - Jul 3, 2007
#8	N/A	-8.75% Dec 3, 2004 - Mar 28, 2005
#9	N/A	-5.73% Feb 21, 2007 - Mar 7, 2007
#10	N/A	-5.34% Dec 8, 2020 - Dec 16, 2020
#11	N/A	-4.94% Mar 28, 2005 - May 11, 2005
#12	N/A	-4.48% Dec 17, 2020 - Dec 21, 2020
#13	N/A	-4.01% Jul 9, 2007 - Jul 13, 2007
#14	N/A	-2.82% Nov 22, 2004 - Nov 24, 2004
#15	N/A	-2.50% Nov 24, 2004 - Dec 1, 2004

Correlation

Correlation between ANTA and SPRO is -0.40 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.40

-101