ALNY vs MTB

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and M & T Bank Corp (MTB, Company).

ALNY is from the Healthcare sector, while MTB is from the Financial Services sector.

5-Year PerformanceMTB has outperformed ALNY, delivering a return of +16.9% compared to +9.8%

ALNY vs MTB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ALNY(COMPANY)	MTB(COMPANY)
Market Cap	$37B	$37B
Max Drawdown	83.58%	75.55%
Sharpe Ratio	-0.24	1.23
5Y Beta	0.80	0.88
Industry	Biotechnology	Banks - Regional
P/E Ratio	117.96	14.12
Forward P/E	32.79	12.97
PEG Ratio	N/A	1.10
Dividend Yield	N/A	2.41%
5Y Dividends CAGR	N/A	10.81%
5Y EPS CAGR	N/A	4.55%
Debt to Equity	0.00%	68.02%
Free Cash Flow Yield	1.26%	9.12%
P/S Ratio	N/A	3.80
P/B Ratio	N/A	1.39

Market Cap

ALNY

$37B

Winner

MTB

$37B

Max Drawdown

ALNY

83.58%

Winner

MTB

75.55%

Sharpe Ratio

ALNY

-0.24

Winner

MTB

1.23

5Y Beta

Winner

ALNY

0.80

MTB

0.88

Industry

ALNY

Biotechnology

MTB

Banks - Regional

P/E Ratio

ALNY

117.96

Winner

MTB

14.12

Forward P/E

ALNY

32.79

Winner

MTB

12.97

PEG Ratio

ALNY

N/A

MTB

1.10

Dividend Yield

ALNY

N/A

MTB

2.41%

5Y Dividends CAGR

ALNY

N/A

MTB

10.81%

5Y EPS CAGR

ALNY

N/A

MTB

4.55%

Debt to Equity

Winner

ALNY

0.00%

MTB

68.02%

Free Cash Flow Yield

ALNY

1.26%

Winner

MTB

9.12%

P/S Ratio

ALNY

N/A

MTB

3.80

P/B Ratio

ALNY

N/A

MTB

1.39

ALNY vs MTB - Historical Returns

Returns include dividend reinvestment.

Period	ALNY	MTB
1 month	+0.44%	+11.28%
3 months	-11.55%	+17.96%
6 months	-21.19%	+21.38%
1 year	-12.29%	+35.91%
5 years(CAGR)	+9.79%	+16.93%
10 years(CAGR)	+15.94%	+11.05%
Max(CAGR)	+18.21%	+9.15%

ALNY

+0.44%

Winner

MTB

+11.28%

ALNY

-11.55%

Winner

MTB

+17.96%

ALNY

-21.19%

Winner

MTB

+21.38%

ALNY

-12.29%

Winner

MTB

+35.91%

5Y(CAGR)

ALNY

+9.79%

Winner

MTB

+16.93%

10Y(CAGR)

Winner

ALNY

+15.94%

MTB

+11.05%

Max(CAGR)

Winner

ALNY

+18.21%

MTB

+9.15%

ALNY vs MTB - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ALNY	MTB
2026	-29.24%	+26.28%
2025	+70.21%	+10.48%
2024	+20.72%	+39.71%
2023	-18.06%	-1.61%
2022	+36.65%	-5.85%
2021	+32.38%	+24.76%
2020	+12.41%	-22.69%
2019	+58.29%	+20.18%
2018	-44.70%	-14.69%
2017	+228.80%	+11.15%
2016	-59.75%	+36.28%
2015	-3.71%	-1.12%
2014	+51.89%	+11.72%
2013	+235.42%	+18.22%
2012	+110.74%	+30.33%
2011	-18.58%	-10.03%
2010	-45.64%	+34.50%
2009	-29.94%	+23.24%
2008	-14.49%	-25.55%
2007	+34.82%	-31.82%
2006	+65.12%	+12.19%
2005	+76.25%	+4.73%
2004	+6.71%	+12.23%
2003	N/A	+22.06%
2002	N/A	+10.99%
2001	N/A	+13.92%
2000	N/A	+69.50%
1999	N/A	-16.09%

ALNY vs MTB Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for MTB was -73.52%, occurring on Mar 5, 2009. Recovery took 1428 trading sessions.

The current ALNY drawdown is -42.36%.

Rank	ALNY	MTB
#1	-83.58% Oct 9, 2007 - Jul 3, 2013	-73.52% Feb 20, 2007 - Oct 17, 2012
#2	-77.36% Jun 22, 2015 - Nov 10, 2017	-52.97% Mar 9, 2018 - Jan 7, 2022
#3	-57.81% Mar 20, 2018 - Jun 19, 2020	-40.69% Sep 12, 2022 - Sep 19, 2024
#4	-52.18% Jun 9, 2004 - Jan 6, 2005	-28.19% Nov 25, 2024 - Jan 8, 2026
#5	-47.61% Jan 13, 2014 - Oct 24, 2014	-26.75% Nov 2, 1999 - Aug 4, 2000
#6	-43.39% Oct 20, 2025 - Jun 18, 2026	-23.95% May 17, 2002 - May 30, 2003
#7	-42.46% Oct 14, 2021 - Aug 3, 2022	-23.47% Jul 22, 2015 - Nov 9, 2016
#8	-40.61% Dec 21, 2022 - Jun 26, 2024	-19.77% Jul 20, 2001 - Mar 14, 2002
#9	-36.52% Mar 29, 2006 - Oct 31, 2006	-18.02% Feb 16, 2022 - Aug 10, 2022
#10	-36.33% Dec 8, 2006 - Jul 11, 2007	-16.99% Feb 6, 2026 - Jun 25, 2026
#11	-34.67% Sep 12, 2005 - Jan 10, 2006	-16.08% Mar 1, 2017 - Dec 1, 2017
#12	-32.55% Jan 10, 2005 - Sep 7, 2005	-15.04% Dec 30, 2003 - Aug 18, 2004
#13	-26.79% Jan 25, 2021 - Jun 18, 2021	-13.61% Jan 14, 2022 - Feb 16, 2022
#14	-26.77% Jul 20, 2020 - Jan 12, 2021	-12.43% Mar 7, 2001 - Mar 30, 2001
#15	-25.36% Oct 16, 2024 - May 30, 2025	-12.30% Dec 5, 2014 - Mar 20, 2015