ALNY vs RVMD

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and Revolution Medicines Inc (RVMD, Company).

Both ALNY and RVMD are from the Healthcare sector.

5-Year PerformanceRVMD has outperformed ALNY, delivering a return of +43.2% compared to +9.8%

ALNY vs RVMD - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ALNY(COMPANY)	RVMD(COMPANY)
Market Cap	$37B	$37B
Max Drawdown	83.58%	73.29%
Sharpe Ratio	-0.24	2.59
5Y Beta	0.80	1.10
Industry	Biotechnology	Biotechnology
P/E Ratio	117.96	-26.15
Forward P/E	32.79	N/A
PEG Ratio	N/A	-0.33
5Y EPS CAGR	N/A	30.12%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	1.26%	-2.90%

Market Cap

Winner

ALNY

$37B

RVMD

$37B

Max Drawdown

ALNY

83.58%

Winner

RVMD

73.29%

Sharpe Ratio

ALNY

-0.24

Winner

RVMD

2.59

5Y Beta

Winner

ALNY

0.80

RVMD

1.10

Industry

ALNY

Biotechnology

RVMD

Biotechnology

P/E Ratio

ALNY

117.96

Winner

RVMD

-26.15

Forward P/E

ALNY

32.79

RVMD

N/A

PEG Ratio

ALNY

N/A

RVMD

-0.33

5Y EPS CAGR

ALNY

N/A

RVMD

30.12%

Debt to Equity

ALNY

0.00%

RVMD

0.00%

Free Cash Flow Yield

Winner

ALNY

1.26%

RVMD

-2.90%

ALNY vs RVMD - Historical Returns

Returns include dividend reinvestment.

Period	ALNY	RVMD
1 month	+0.44%	+14.43%
3 months	-11.55%	+20.04%
6 months	-21.19%	+48.97%
1 year	-12.29%	+366.61%
5 years(CAGR)	+9.79%	+43.16%
10 years(CAGR)	+15.94%	N/A
Max(CAGR)	+18.21%	+32.87%

ALNY

+0.44%

Winner

RVMD

+14.43%

ALNY

-11.55%

Winner

RVMD

+20.04%

ALNY

-21.19%

Winner

RVMD

+48.97%

ALNY

-12.29%

Winner

RVMD

+366.61%

5Y(CAGR)

ALNY

+9.79%

Winner

RVMD

+43.16%

10Y(CAGR)

ALNY

+15.94%

RVMD

N/A

Max(CAGR)

ALNY

+18.21%

Winner

RVMD

+32.87%

ALNY vs RVMD - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	ALNY	RVMD
2026	-29.24%	+126.75%
2025	+70.21%	+81.02%
2024	+20.72%	+54.94%
2023	-18.06%	+24.97%
2022	+36.65%	-8.94%
2021	+32.38%	-33.64%
2020	+12.41%	+36.99%
2019	+58.29%	N/A
2018	-44.70%	N/A
2017	+228.80%	N/A
2016	-59.75%	N/A
2015	-3.71%	N/A
2014	+51.89%	N/A
2013	+235.42%	N/A
2012	+110.74%	N/A
2011	-18.58%	N/A
2010	-45.64%	N/A
2009	-29.94%	N/A
2008	-14.49%	N/A
2007	+34.82%	N/A
2006	+65.12%	N/A
2005	+76.25%	N/A
2004	+6.71%	N/A

ALNY vs RVMD Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for RVMD was -73.29%, occurring on May 12, 2022. Recovery took 940 trading sessions.

The current ALNY drawdown is -42.36%. The current RVMD drawdown is -6.98%.

Rank	ALNY	RVMD
#1	-83.58% Oct 9, 2007 - Jul 3, 2013	-73.29% Feb 8, 2021 - Nov 1, 2024
#2	-77.36% Jun 22, 2015 - Nov 10, 2017	-48.63% Nov 11, 2024 - Nov 6, 2025
#3	-57.81% Mar 20, 2018 - Jun 19, 2020	-42.53% Jun 22, 2020 - Oct 6, 2020
#4	-52.18% Jun 9, 2004 - Jan 6, 2005	-42.34% Mar 4, 2020 - May 5, 2020
#5	-47.61% Jan 13, 2014 - Oct 24, 2014	-33.63% Oct 16, 2020 - Feb 2, 2021
#6	-43.39% Oct 20, 2025 - Jun 18, 2026	-24.95% Jan 15, 2026 - Apr 13, 2026
#7	-42.46% Oct 14, 2021 - Aug 3, 2022	-20.32% May 7, 2020 - Jun 15, 2020
#8	-40.61% Dec 21, 2022 - Jun 26, 2024	-13.68% Apr 15, 2026 - May 21, 2026
#9	-36.52% Mar 29, 2006 - Oct 31, 2006	-11.91% Jun 1, 2026 - Jun 22, 2026
#10	-36.33% Dec 8, 2006 - Jul 11, 2007	-6.98% Jun 29, 2026 - Jul 16, 2026
#11	-34.67% Sep 12, 2005 - Jan 10, 2006	-5.89% Jun 15, 2020 - Jun 22, 2020
#12	-32.55% Jan 10, 2005 - Sep 7, 2005	-5.73% Feb 26, 2020 - Mar 4, 2020
#13	-26.79% Jan 25, 2021 - Jun 18, 2021	-5.12% Dec 8, 2025 - Dec 22, 2025
#14	-26.77% Jul 20, 2020 - Jan 12, 2021	-3.52% Dec 24, 2025 - Jan 7, 2026
#15	-25.36% Oct 16, 2024 - May 30, 2025	-3.15% Nov 28, 2025 - Dec 4, 2025