ALNY vs WAT

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and Waters Corp (WAT, Company).

Both ALNY and WAT are from the Healthcare sector.

5-Year PerformanceALNY has outperformed WAT, delivering a return of +9.8% compared to +0.4%

ALNY vs WAT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ALNY(COMPANY)	WAT(COMPANY)
Market Cap	$37B	$37B
Max Drawdown	83.58%	80.12%
Sharpe Ratio	-0.24	0.65
5Y Beta	0.80	0.94
Industry	Biotechnology	Diagnostics & Research
P/E Ratio	117.96	102.79
Forward P/E	32.79	25.84
PEG Ratio	N/A	1.42
5Y EPS CAGR	N/A	15.00%
Debt to Equity	0.00%	31.75%
Free Cash Flow Yield	1.26%	1.06%

Market Cap

Winner

ALNY

$37B

WAT

$37B

Max Drawdown

ALNY

83.58%

Winner

WAT

80.12%

Sharpe Ratio

ALNY

-0.24

Winner

WAT

0.65

5Y Beta

Winner

ALNY

0.80

WAT

0.94

Industry

ALNY

Biotechnology

WAT

Diagnostics & Research

P/E Ratio

ALNY

117.96

Winner

WAT

102.79

Forward P/E

ALNY

32.79

Winner

WAT

25.84

PEG Ratio

ALNY

N/A

WAT

1.42

5Y EPS CAGR

ALNY

N/A

WAT

15.00%

Debt to Equity

Winner

ALNY

0.00%

WAT

31.75%

Free Cash Flow Yield

Winner

ALNY

1.26%

WAT

1.06%

ALNY vs WAT - Historical Returns

Returns include dividend reinvestment.

Period	ALNY	WAT
1 month	+0.44%	+4.90%
3 months	-11.55%	+18.54%
6 months	-21.19%	-2.37%
1 year	-12.29%	+30.61%
5 years(CAGR)	+9.79%	+0.40%
10 years(CAGR)	+15.94%	+9.77%
Max(CAGR)	+18.21%	+10.66%

ALNY

+0.44%

Winner

WAT

+4.90%

ALNY

-11.55%

Winner

WAT

+18.54%

ALNY

-21.19%

Winner

WAT

-2.37%

ALNY

-12.29%

Winner

WAT

+30.61%

5Y(CAGR)

Winner

ALNY

+9.79%

WAT

+0.40%

10Y(CAGR)

Winner

ALNY

+15.94%

WAT

+9.77%

Max(CAGR)

Winner

ALNY

+18.21%

WAT

+10.66%

ALNY vs WAT - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ALNY	WAT
2026	-29.24%	-0.99%
2025	+70.21%	+3.14%
2024	+20.72%	+12.89%
2023	-18.06%	-4.73%
2022	+36.65%	-6.04%
2021	+32.38%	+48.95%
2020	+12.41%	+5.26%
2019	+58.29%	+27.39%
2018	-44.70%	-3.60%
2017	+228.80%	+41.60%
2016	-59.75%	+3.10%
2015	-3.71%	+18.18%
2014	+51.89%	+13.61%
2013	+235.42%	+12.73%
2012	+110.74%	+14.72%
2011	-18.58%	-5.19%
2010	-45.64%	+26.09%
2009	-29.94%	+62.67%
2008	-14.49%	-52.25%
2007	+34.82%	+61.76%
2006	+65.12%	+28.53%
2005	+76.25%	-17.41%
2004	+6.71%	+41.27%
2003	N/A	+50.59%
2002	N/A	-43.79%
2001	N/A	-50.87%
2000	N/A	+224.27%
1999	N/A	+4.83%

ALNY vs WAT Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for WAT was -80.12%, occurring on Jul 22, 2002. Recovery took 2656 trading sessions.

The current ALNY drawdown is -42.36%. The current WAT drawdown is -10.95%.

Rank	ALNY	WAT
#1	-83.58% Oct 9, 2007 - Jul 3, 2013	-80.12% Sep 28, 2000 - Apr 21, 2011
#2	-77.36% Jun 22, 2015 - Nov 10, 2017	-44.27% Sep 8, 2021 - Oct 30, 2023
#3	-57.81% Mar 20, 2018 - Jun 19, 2020	-35.86% Apr 8, 2019 - Jan 5, 2021
#4	-52.18% Jun 9, 2004 - Jan 6, 2005	-28.07% May 19, 2011 - Jun 17, 2013
#5	-47.61% Jan 13, 2014 - Oct 24, 2014	-27.49% Mar 6, 2000 - Jun 2, 2000
#6	-43.39% Oct 20, 2025 - Jun 18, 2026	-20.65% Jan 29, 2018 - Jan 23, 2019
#7	-42.46% Oct 14, 2021 - Aug 3, 2022	-19.26% Jul 12, 2000 - Aug 21, 2000
#8	-40.61% Dec 21, 2022 - Jun 26, 2024	-17.37% Aug 23, 2016 - Apr 25, 2017
#9	-36.52% Mar 29, 2006 - Oct 31, 2006	-17.28% Feb 20, 2014 - Nov 20, 2014
#10	-36.33% Dec 8, 2006 - Jul 11, 2007	-16.98% Dec 31, 1999 - Jan 25, 2000
#11	-34.67% Sep 12, 2005 - Jan 10, 2006	-16.76% Jun 18, 2015 - Apr 18, 2016
#12	-32.55% Jan 10, 2005 - Sep 7, 2005	-13.96% Nov 1, 1999 - Dec 29, 1999
#13	-26.79% Jan 25, 2021 - Jun 18, 2021	-13.28% Aug 28, 2000 - Sep 25, 2000
#14	-26.77% Jul 20, 2020 - Jan 12, 2021	-11.58% Sep 26, 2013 - Jan 28, 2014
#15	-25.36% Oct 16, 2024 - May 30, 2025	-10.25% Feb 17, 2000 - Feb 25, 2000