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ALNY vs SPY

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceALNY has outperformed SPY, delivering a return of +17.6% compared to +13.3%

ALNY vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
ALNY
$40B
Winner
SPY
$652B
Expense Ratio
ALNY
N/A
SPY
0.09%
Max Drawdown
ALNY
83.58%
Winner
SPY
56.47%
Sharpe Ratio
ALNY
0.26
Winner
SPY
2.07
5Y Beta
Winner
ALNY
0.81
SPY
1.00
Industry
ALNY
Biotechnology
SPY
N/A
P/E Ratio
ALNY
128.05
Winner
SPY
28.24
Forward P/E
ALNY
31.95
Winner
SPY
21.85
PEG Ratio
ALNY
0.51
SPY
N/A
5Y Dividends CAGR
ALNY
N/A
SPY
5.43%
5Y EPS CAGR
ALNY
N/A
SPY
25.79%
Debt to Equity
Winner
ALNY
0.00%
SPY
22.35%
Free Cash Flow Yield
ALNY
1.16%
SPY
N/A
P/S Ratio
ALNY
9.44
Winner
SPY
3.55
P/B Ratio
ALNY
37.38
Winner
SPY
5.29

ALNY vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
ALNY
-9.84%
Winner
SPY
+9.11%
3M
ALNY
-7.80%
Winner
SPY
+6.59%
6M
ALNY
-33.35%
Winner
SPY
+10.56%
1Y
ALNY
+14.21%
Winner
SPY
+32.04%
5Y(CAGR)
Winner
ALNY
+17.57%
SPY
+13.35%
10Y(CAGR)
Winner
ALNY
+17.71%
SPY
+15.49%
Max(CAGR)
Winner
ALNY
+18.60%
SPY
+8.50%

ALNY vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearALNYSPY
2026-26.27%+8.27%
2025+70.21%+18.00%
2024+20.72%+25.59%
2023-18.06%+26.72%
2022+36.65%-18.64%
2021+32.38%+30.52%
2020+12.41%+17.28%
2019+58.29%+31.09%
2018-44.70%-5.24%
2017+228.80%+20.78%
2016-59.75%+13.59%
2015-3.71%+1.31%
2014+51.89%+14.56%
2013+235.42%+29.00%
2012+110.74%+14.17%
2011-18.58%+0.85%
2010-45.64%+13.14%
2009-29.94%+22.67%
2008-14.49%-36.25%
2007+34.82%+5.32%
2006+65.12%+13.85%
2005+76.25%+5.32%
2004+6.71%+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

ALNY vs SPY Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current ALNY drawdown is -39.94%.

RankALNYSPY
#1-83.58%
Oct 9, 2007 - Jul 3, 2013
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-77.36%
Jun 22, 2015 - Nov 10, 2017
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-57.81%
Mar 20, 2018 - Jun 19, 2020
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-52.18%
Jun 9, 2004 - Jan 6, 2005
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-47.61%
Jan 13, 2014 - Oct 24, 2014
-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-42.46%
Oct 14, 2021 - Aug 3, 2022
-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-40.61%
Dec 21, 2022 - Jun 26, 2024
-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-39.94%
Oct 20, 2025 - May 8, 2026
-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-36.52%
Mar 29, 2006 - Oct 31, 2006
-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-36.33%
Dec 8, 2006 - Jul 11, 2007
-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-34.67%
Sep 12, 2005 - Jan 10, 2006
-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-32.55%
Jan 10, 2005 - Sep 7, 2005
-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-26.79%
Jan 25, 2021 - Jun 18, 2021
-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-26.77%
Jul 20, 2020 - Jan 12, 2021
-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-25.36%
Oct 16, 2024 - May 30, 2025
-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between ALNY and SPY is 0.95 which considered as a very strong positive correlation - the stocks move almost identically together.

0.95
-101

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