AGNCM vs PTGX

Comparison between AGNC Investment Corp (AGNCM, Company) and Protagonist Therapeutics Inc (PTGX, Company).

AGNCM is from the Real Estate sector, while PTGX is from the Healthcare sector.

5-Year PerformancePTGX has outperformed AGNCM, delivering a return of +24.8% compared to +7.6%

AGNCM vs PTGX - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	AGNCM(COMPANY)	PTGX(COMPANY)
Market Cap	$8.87B	$8.88B
Max Drawdown	56.16%	85.79%
Sharpe Ratio	0.93	2.09
5Y Beta	0.12	0.24
Industry	Reit - Mortgage	Biotechnology
P/E Ratio	30.46	110.94
Forward P/E	N/A	30.96
PEG Ratio	N/A	2.44
Dividend Yield	5.73%	N/A
5Y Dividends CAGR	9.54%	N/A
Debt to Equity	N/A	0.00%
Free Cash Flow Yield	N/A	1.47%
P/S Ratio	4.94	117.93
P/B Ratio	2.30	13.40

Market Cap

AGNCM

$8.87B

Winner

PTGX

$8.88B

Max Drawdown

Winner

AGNCM

56.16%

PTGX

85.79%

Sharpe Ratio

AGNCM

0.93

Winner

PTGX

2.09

5Y Beta

Winner

AGNCM

0.12

PTGX

0.24

Industry

AGNCM

Reit - Mortgage

PTGX

Biotechnology

P/E Ratio

Winner

AGNCM

30.46

PTGX

110.94

Forward P/E

AGNCM

N/A

PTGX

30.96

PEG Ratio

AGNCM

N/A

PTGX

2.44

Dividend Yield

AGNCM

5.73%

PTGX

N/A

5Y Dividends CAGR

AGNCM

9.54%

PTGX

N/A

Debt to Equity

AGNCM

N/A

PTGX

0.00%

Free Cash Flow Yield

AGNCM

N/A

PTGX

1.47%

P/S Ratio

Winner

AGNCM

4.94

PTGX

117.93

P/B Ratio

Winner

AGNCM

2.30

PTGX

13.40

AGNCM vs PTGX - Historical Returns

Returns include dividend reinvestment.

Period	AGNCM	PTGX
1 month	+1.08%	+3.56%
3 months	+2.89%	+47.57%
6 months	+5.05%	+72.65%
1 year	+9.17%	+186.24%
5 years(CAGR)	+7.57%	+24.83%
10 years(CAGR)	N/A	+28.74%
Max(CAGR)	+8.31%	+28.74%

AGNCM

+1.08%

Winner

PTGX

+3.56%

AGNCM

+2.89%

Winner

PTGX

+47.57%

AGNCM

+5.05%

Winner

PTGX

+72.65%

AGNCM

+9.17%

Winner

PTGX

+186.24%

5Y(CAGR)

AGNCM

+7.57%

Winner

PTGX

+24.83%

10Y(CAGR)

AGNCM

N/A

PTGX

+28.74%

Max(CAGR)

AGNCM

+8.31%

Winner

PTGX

+28.74%

AGNCM vs PTGX - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	AGNCM	PTGX
2026	+6.24%	+67.32%
2025	+6.51%	+124.06%
2024	+16.94%	+64.82%
2023	+25.53%	+112.71%
2022	-16.89%	-69.11%
2021	+12.21%	+74.49%
2020	+3.83%	+190.91%
2019	+9.96%	+2.32%
2018	N/A	-68.18%
2017	N/A	-1.79%
2016	N/A	+87.95%

AGNCM vs PTGX Drawdown Comparison

The maximum drawdown for AGNCM was -55.99%, occurring on Mar 18, 2020. Recovery took 226 trading sessions.

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The current PTGX drawdown is -0.21%.

Rank	AGNCM	PTGX
#1	-55.99% Feb 3, 2020 - Dec 23, 2020	-85.79% Sep 1, 2021 - Mar 10, 2025
#2	-28.38% Jan 3, 2022 - Jul 28, 2023	-82.13% Dec 5, 2016 - Feb 16, 2021
#3	-13.96% Sep 29, 2023 - Dec 26, 2023	-31.58% Mar 11, 2025 - Aug 27, 2025
#4	-6.49% Apr 1, 2025 - Jun 20, 2025	-20.33% Oct 17, 2016 - Nov 10, 2016
#5	-3.93% Jul 12, 2021 - Dec 31, 2021	-19.04% Mar 19, 2021 - May 18, 2021
#6	-3.65% Feb 18, 2026 - Apr 15, 2026	-16.38% Dec 12, 2025 - Mar 9, 2026
#7	-3.32% May 7, 2021 - Jun 9, 2021	-15.52% Oct 10, 2025 - Nov 24, 2025
#8	-3.04% Dec 30, 2020 - Mar 5, 2021	-12.77% Feb 16, 2021 - Mar 2, 2021
#9	-2.45% Aug 29, 2019 - Dec 18, 2019	-12.03% Apr 17, 2026 - Jun 11, 2026
#10	-2.36% Oct 7, 2025 - Dec 17, 2025	-11.53% Aug 19, 2016 - Aug 31, 2016
#11	-2.03% Aug 2, 2023 - Aug 24, 2023	-9.62% Jun 8, 2021 - Jun 11, 2021
#12	-1.97% Jun 24, 2025 - Jul 15, 2025	-8.53% Aug 27, 2025 - Sep 18, 2025
#13	-1.88% Dec 31, 2024 - Apr 1, 2025	-7.78% Jul 7, 2026 - Jul 17, 2026
#14	-1.82% Apr 21, 2021 - May 4, 2021	-7.43% Mar 31, 2026 - Apr 15, 2026
#15	-1.63% Dec 28, 2023 - Jan 8, 2024	-7.20% Jun 14, 2021 - Jun 16, 2021