AAOI vs PTGX

Comparison between Applied Optoelectronics Inc (AAOI, Company) and Protagonist Therapeutics Inc (PTGX, Company).

AAOI is from the Technology sector, while PTGX is from the Healthcare sector.

5-Year PerformanceAAOI has outperformed PTGX, delivering a return of +71.7% compared to +23.2%

AAOI vs PTGX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AAOI(COMPANY)	PTGX(COMPANY)
Market Cap	$9.04B	$9B
Max Drawdown	98.49%	85.79%
Sharpe Ratio	1.68	1.98
5Y Beta	3.81	0.24
Industry	Communication Equipment	Biotechnology
P/E Ratio	-185.08	-76.12
Forward P/E	84.03	29.15
PEG Ratio	0.78	0.00
5Y EPS CAGR	-23.67%	1.43%
Debt to Equity	3.73%	0.00%
Free Cash Flow Yield	-4.62%	-1.31%
P/S Ratio	18.11	121.63
P/B Ratio	8.78	13.82

Market Cap

Winner

AAOI

$9.04B

PTGX

$9B

Max Drawdown

AAOI

98.49%

Winner

PTGX

85.79%

Sharpe Ratio

AAOI

1.68

Winner

PTGX

1.98

5Y Beta

AAOI

3.81

Winner

PTGX

0.24

Industry

AAOI

Communication Equipment

PTGX

Biotechnology

P/E Ratio

Winner

AAOI

-185.08

PTGX

-76.12

Forward P/E

AAOI

84.03

Winner

PTGX

29.15

PEG Ratio

AAOI

0.78

Winner

PTGX

0.00

5Y EPS CAGR

AAOI

-23.67%

Winner

PTGX

1.43%

Debt to Equity

AAOI

3.73%

Winner

PTGX

0.00%

Free Cash Flow Yield

AAOI

-4.62%

Winner

PTGX

-1.31%

P/S Ratio

Winner

AAOI

18.11

PTGX

121.63

P/B Ratio

Winner

AAOI

8.78

PTGX

13.82

AAOI vs PTGX - Historical Returns

Returns include dividend reinvestment.

Period	AAOI	PTGX
1 month	-31.53%	+24.25%
3 months	-20.37%	+32.99%
6 months	+252.29%	+63.82%
1 year	+324.50%	+148.78%
5 years(CAGR)	+71.73%	+23.25%
10 years(CAGR)	+26.92%	+27.64%
Max(CAGR)	+21.48%	+27.64%

AAOI

-31.53%

Winner

PTGX

+24.25%

AAOI

-20.37%

Winner

PTGX

+32.99%

Winner

AAOI

+252.29%

PTGX

+63.82%

Winner

AAOI

+324.50%

PTGX

+148.78%

5Y(CAGR)

Winner

AAOI

+71.73%

PTGX

+23.25%

10Y(CAGR)

AAOI

+26.92%

Winner

PTGX

+27.64%

Max(CAGR)

AAOI

+21.48%

Winner

PTGX

+27.64%

AAOI vs PTGX - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	AAOI	PTGX
2026	+202.83%	+50.75%
2025	-2.08%	+124.06%
2024	+97.22%	+64.82%
2023	+927.66%	+112.71%
2022	-64.14%	-69.11%
2021	-41.32%	+74.49%
2020	-31.92%	+190.91%
2019	-25.19%	+2.32%
2018	-59.30%	-68.18%
2017	+63.72%	-1.79%
2016	+43.89%	+87.95%
2015	+59.04%	N/A
2014	-23.31%	N/A
2013	+50.70%	N/A

AAOI vs PTGX Drawdown Comparison

The maximum drawdown for AAOI was -98.49%, occurring on Jul 11, 2022. Recovery took 2156 trading sessions.

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The current AAOI drawdown is -46.25%. The current PTGX drawdown is -6.70%.

Rank	AAOI	PTGX
#1	-98.49% Aug 1, 2017 - Mar 2, 2026	-85.79% Sep 1, 2021 - Mar 10, 2025
#2	-69.44% Mar 10, 2014 - Jan 12, 2017	-82.13% Dec 5, 2016 - Feb 16, 2021
#3	-48.72% May 13, 2026 - Jul 7, 2026	-31.58% Mar 11, 2025 - Aug 27, 2025
#4	-33.40% Mar 11, 2026 - Apr 8, 2026	-20.33% Oct 17, 2016 - Nov 10, 2016
#5	-31.83% Mar 27, 2017 - May 9, 2017	-19.04% Mar 19, 2021 - May 18, 2021
#6	-21.75% Jun 2, 2017 - Jul 13, 2017	-16.38% Dec 12, 2025 - Mar 9, 2026
#7	-20.81% Dec 11, 2013 - Feb 20, 2014	-15.52% Oct 10, 2025 - Nov 24, 2025
#8	-18.84% May 1, 2026 - May 11, 2026	-12.77% Feb 16, 2021 - Mar 2, 2021
#9	-16.03% Apr 20, 2026 - Apr 30, 2026	-12.03% Apr 17, 2026 - Jun 11, 2026
#10	-13.09% Mar 7, 2017 - Mar 24, 2017	-11.53% Aug 19, 2016 - Aug 31, 2016
#11	-9.60% Oct 22, 2013 - Nov 29, 2013	-9.62% Jun 8, 2021 - Jun 11, 2021
#12	-7.11% Feb 21, 2014 - Feb 28, 2014	-8.53% Aug 27, 2025 - Sep 18, 2025
#13	-6.99% Mar 2, 2026 - Mar 9, 2026	-7.43% Mar 31, 2026 - Apr 15, 2026
#14	-6.95% Apr 13, 2026 - Apr 16, 2026	-7.20% Jun 14, 2021 - Jun 16, 2021
#15	-6.67% Nov 29, 2013 - Dec 6, 2013	-6.70% Jul 7, 2026 - Jul 10, 2026