PTGX vs APLD

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Applied Digital Corporation (APLD, Company).

PTGX is from the Healthcare sector, while APLD is from the Technology sector.

5-Year PerformanceAPLD has outperformed PTGX, delivering a return of +24.4% compared to +23.2%

PTGX vs APLD - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	APLD(COMPANY)
Market Cap	$9B	$8.97B
Max Drawdown	85.79%	99.70%
Sharpe Ratio	1.98	1.60
5Y Beta	0.24	2.78
Industry	Biotechnology	Information Technology Services
P/E Ratio	-76.12	-52.80
Forward P/E	29.15	526.32
PEG Ratio	0.00	1.83
5Y EPS CAGR	1.43%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-1.31%	-0.40%
P/S Ratio	121.63	27.13
P/B Ratio	13.82	5.97

Market Cap

Winner

PTGX

$9B

APLD

$8.97B

Max Drawdown

Winner

PTGX

85.79%

APLD

99.70%

Sharpe Ratio

Winner

PTGX

1.98

APLD

1.60

5Y Beta

Winner

PTGX

0.24

APLD

2.78

Industry

PTGX

Biotechnology

APLD

Information Technology Services

P/E Ratio

Winner

PTGX

-76.12

APLD

-52.80

Forward P/E

Winner

PTGX

29.15

APLD

526.32

PEG Ratio

Winner

PTGX

0.00

APLD

1.83

5Y EPS CAGR

PTGX

1.43%

APLD

N/A

Debt to Equity

PTGX

0.00%

APLD

0.00%

Free Cash Flow Yield

PTGX

-1.31%

Winner

APLD

-0.40%

P/S Ratio

PTGX

121.63

Winner

APLD

27.13

P/B Ratio

PTGX

13.82

Winner

APLD

5.97

PTGX vs APLD - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	APLD
1 month	+24.25%	-19.96%
3 months	+32.99%	+18.62%
6 months	+63.82%	-17.33%
1 year	+148.78%	+233.87%
5 years(CAGR)	+23.25%	+24.43%
10 years(CAGR)	+27.64%	+83.54%
Max(CAGR)	+27.64%	+15.57%

Winner

PTGX

+24.25%

APLD

-19.96%

Winner

PTGX

+32.99%

APLD

+18.62%

Winner

PTGX

+63.82%

APLD

-17.33%

PTGX

+148.78%

Winner

APLD

+233.87%

5Y(CAGR)

PTGX

+23.25%

Winner

APLD

+24.43%

10Y(CAGR)

PTGX

+27.64%

Winner

APLD

+83.54%

Max(CAGR)

Winner

PTGX

+27.64%

APLD

+15.57%

PTGX vs APLD - Annual Returns (2008 - 2026)

Returns include dividend reinvestment.

Year	PTGX	APLD
2026	+50.75%	+10.81%
2025	+124.06%	+214.36%
2024	+64.82%	+9.77%
2023	+112.71%	+266.30%
2022	-69.11%	-92.45%
2021	+74.49%	+11073.33%
2020	+190.91%	+389.35%
2019	+2.32%	-35.14%
2018	-68.18%	+83.33%
2017	-1.79%	-33.33%
2016	+87.95%	-41.18%
2015	N/A	+68.32%
2014	N/A	+461.11%
2013	N/A	-81.82%
2012	N/A	+108.33%
2011	N/A	-98.29%
2010	N/A	-22.22%
2009	N/A	+380.00%
2008	N/A	-93.75%

PTGX vs APLD Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for APLD was -99.70%, occurring on Dec 30, 2011. Recovery took 2705 trading sessions.

The current PTGX drawdown is -6.70%. The current APLD drawdown is -37.26%.

Rank	PTGX	APLD
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-99.70% Oct 22, 2008 - Apr 16, 2021
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-97.10% Oct 26, 2021 - Oct 10, 2025
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-61.84% May 3, 2021 - Aug 27, 2021
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-50.31% Jan 27, 2026 - May 6, 2026
#5	-19.04% Mar 19, 2021 - May 18, 2021	-44.15% Oct 15, 2025 - Jan 12, 2026
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-38.87% Aug 27, 2021 - Oct 7, 2021
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-38.15% May 28, 2026 - Jul 7, 2026
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-36.31% Apr 27, 2021 - May 3, 2021
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-32.28% Apr 16, 2021 - Apr 20, 2021
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-21.60% May 14, 2026 - May 21, 2026
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-9.08% Jan 12, 2026 - Jan 27, 2026
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-7.46% Oct 13, 2021 - Oct 18, 2021
#13	-7.43% Mar 31, 2026 - Apr 15, 2026	-6.76% May 6, 2026 - May 11, 2026
#14	-7.20% Jun 14, 2021 - Jun 16, 2021	-6.00% May 21, 2026 - May 27, 2026
#15	-6.70% Jul 7, 2026 - Jul 10, 2026	-1.48% May 11, 2026 - May 13, 2026