ZBIO vs TYRA
Comparison between Zenas Biopharma Inc (ZBIO, Company) and Tyra Biosciences Inc (TYRA, Company).
Both ZBIO and TYRA are from the Healthcare sector.
ZBIO vs TYRA - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
ZBIO
$1.75B
Winner
TYRA
$1.75B
Max Drawdown
Winner
ZBIO
74.96%
TYRA
83.22%
Sharpe Ratio
ZBIO
1.56
Winner
TYRA
2.14
5Y Beta
ZBIO
1.26
Winner
TYRA
1.04
Industry
ZBIO
Biotechnology
TYRA
Biotechnology
P/E Ratio
ZBIO
-3.43
Winner
TYRA
-12.36
PEG Ratio
ZBIO
N/A
TYRA
-0.43
Debt to Equity
ZBIO
0.00%
TYRA
0.00%
Free Cash Flow Yield
ZBIO
-12.05%
Winner
TYRA
-5.86%
P/S Ratio
ZBIO
119.50
TYRA
N/A
P/B Ratio
ZBIO
5.26
Winner
TYRA
4.51
ZBIO vs TYRA - Historical Returns
Returns include dividend reinvestment.
1M
Winner
ZBIO
+58.96%
TYRA
+6.84%
3M
Winner
ZBIO
+26.89%
TYRA
-22.70%
6M
ZBIO
-21.07%
Winner
TYRA
+14.30%
1Y
ZBIO
+166.44%
Winner
TYRA
+204.68%
5Y(CAGR)
ZBIO
N/A
TYRA
+3.47%
Max(CAGR)
Winner
ZBIO
+25.30%
TYRA
+3.47%
ZBIO vs TYRA - Annual Returns (2021 - 2026)
Returns include dividend reinvestment.
| Year | ZBIO | TYRA |
|---|---|---|
| 2026 | -21.07% | +14.30% |
| 2025 | +303.00% | +82.19% |
| 2024 | -54.88% | -1.00% |
| 2023 | N/A | +95.90% |
| 2022 | N/A | -46.06% |
| 2021 | N/A | -45.88% |
ZBIO vs TYRA Drawdown Comparison
The maximum drawdown for ZBIO was -74.96%, occurring on Jan 28, 2025. Recovery took 240 trading sessions.
The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.
The current ZBIO drawdown is -36.92%. The current TYRA drawdown is -22.70%.
| Rank | ZBIO | TYRA |
|---|---|---|
| #1 | -74.96% Oct 22, 2024 - Oct 8, 2025 | -83.22% Nov 4, 2021 - Jan 27, 2026 |
| #2 | -64.79% Dec 24, 2025 - Jan 6, 2026 | -48.23% Sep 15, 2021 - Nov 3, 2021 |
| #3 | -19.71% Dec 12, 2025 - Dec 22, 2025 | -35.82% Apr 2, 2026 - Jun 10, 2026 |
| #4 | -14.88% Nov 26, 2025 - Dec 12, 2025 | -13.45% Jan 29, 2026 - Feb 23, 2026 |
| #5 | -13.92% Oct 9, 2025 - Oct 27, 2025 | -9.38% Mar 19, 2026 - Mar 31, 2026 |
| #6 | -12.01% Sep 24, 2024 - Oct 15, 2024 | -5.74% Feb 25, 2026 - Mar 4, 2026 |
| #7 | -11.92% Oct 27, 2025 - Nov 6, 2025 | -4.31% Mar 4, 2026 - Mar 11, 2026 |
| #8 | -6.22% Nov 19, 2025 - Nov 24, 2025 | -1.48% Mar 11, 2026 - Mar 16, 2026 |
| #9 | -3.47% Sep 13, 2024 - Sep 20, 2024 | -1.02% Jan 27, 2026 - Jan 29, 2026 |
| #10 | -3.39% Nov 7, 2025 - Nov 11, 2025 | -0.05% Mar 31, 2026 - Apr 2, 2026 |
| #11 | -2.23% Nov 12, 2025 - Nov 17, 2025 | N/A |
| #12 | -2.16% Sep 20, 2024 - Sep 24, 2024 | N/A |
| #13 | -1.27% Oct 15, 2024 - Oct 17, 2024 | N/A |
| #14 | -0.56% Oct 17, 2024 - Oct 21, 2024 | N/A |
Correlation
Correlation between ZBIO and TYRA is 0.53 which considered as a moderate positive correlation - the stocks show some tendency to move together.
0.53
-101
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