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ZBIO vs SPY

Comparison between Zenas Biopharma Inc (ZBIO, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

ZBIO vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
ZBIO
$1.12B
Winner
SPY
$784B
Expense Ratio
ZBIO
N/A
SPY
0.09%
Max Drawdown
ZBIO
74.96%
Winner
SPY
56.47%
Sharpe Ratio
ZBIO
0.94
Winner
SPY
1.50
5Y Beta
ZBIO
1.30
Winner
SPY
1.00
Industry
ZBIO
Biotechnology
SPY
N/A
P/E Ratio
Winner
ZBIO
-2.19
SPY
28.29
Forward P/E
ZBIO
N/A
SPY
21.76
5Y Dividends CAGR
ZBIO
N/A
SPY
5.43%
5Y EPS CAGR
ZBIO
N/A
SPY
25.98%
Debt to Equity
Winner
ZBIO
0.00%
SPY
30.79%
Free Cash Flow Yield
ZBIO
-18.84%
SPY
N/A
P/S Ratio
ZBIO
119.50
Winner
SPY
3.79
P/B Ratio
Winner
ZBIO
3.36
SPY
5.67

ZBIO vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
ZBIO
+3.34%
SPY
+0.48%
3M
ZBIO
-19.18%
Winner
SPY
+11.67%
6M
ZBIO
-51.22%
Winner
SPY
+9.42%
1Y
Winner
ZBIO
+74.91%
SPY
+24.27%
5Y(CAGR)
ZBIO
N/A
SPY
+13.36%
10Y(CAGR)
ZBIO
N/A
SPY
+15.42%
Max(CAGR)
ZBIO
+5.12%
Winner
SPY
+8.49%

ZBIO vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearZBIOSPY
2026-42.61%+8.88%
2025+303.00%+18.00%
2024-54.88%+25.59%
2023N/A+26.72%
2022N/A-18.64%
2021N/A+30.52%
2020N/A+17.28%
2019N/A+31.09%
2018N/A-5.24%
2017N/A+20.78%
2016N/A+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

ZBIO vs SPY Drawdown Comparison

The maximum drawdown for ZBIO was -74.96%, occurring on Jan 28, 2025. Recovery took 240 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current ZBIO drawdown is -54.13%. The current SPY drawdown is -2.35%.

RankZBIOSPY
#1-74.96%
Oct 22, 2024 - Oct 8, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-64.79%
Dec 24, 2025 - Jan 6, 2026		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-19.71%
Dec 12, 2025 - Dec 22, 2025		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-14.88%
Nov 26, 2025 - Dec 12, 2025		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-13.92%
Oct 9, 2025 - Oct 27, 2025		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-12.01%
Sep 24, 2024 - Oct 15, 2024		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-11.92%
Oct 27, 2025 - Nov 6, 2025		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-6.22%
Nov 19, 2025 - Nov 24, 2025		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-3.47%
Sep 13, 2024 - Sep 20, 2024		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-3.39%
Nov 7, 2025 - Nov 11, 2025		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-2.23%
Nov 12, 2025 - Nov 17, 2025		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-2.16%
Sep 20, 2024 - Sep 24, 2024		-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-1.27%
Oct 15, 2024 - Oct 17, 2024		-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-0.56%
Oct 17, 2024 - Oct 21, 2024		-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between ZBIO and SPY is 0.58 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.58
-101

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