XBI vs URTH
Comparison between SPDR(R) S&P(R) BIOTECH ETF (XBI, ETF) and ISHARES MSCI WORLD ETF (URTH, ETF).
5-Year PerformanceURTH has outperformed XBI, delivering a return of +11.6% compared to +1.2%
XBI vs URTH - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
Winner
XBI
$7.40B
URTH
$7.30B
Expense Ratio
XBI
0.35%
Winner
URTH
0.24%
Max Drawdown
XBI
63.90%
Winner
URTH
34.01%
Sharpe Ratio
Winner
XBI
2.19
URTH
1.94
5Y Beta
XBI
0.97
Winner
URTH
0.91
P/E Ratio
Winner
XBI
-10.99
URTH
26.12
Forward P/E
Winner
XBI
11.82
URTH
20.25
5Y Dividends CAGR
Winner
XBI
9.74%
URTH
7.99%
5Y EPS CAGR
XBI
5.78%
Winner
URTH
24.38%
Debt to Equity
XBI
37.46%
Winner
URTH
21.61%
P/S Ratio
XBI
8.33
Winner
URTH
3.26
P/B Ratio
XBI
4.84
Winner
URTH
4.71
XBI vs URTH - Holdings Comparison
XBI and URTH have 13 common holdings. Overlap is 1.09%
XBI's top 25 holdings weight is 32.10%. URTH's top 25 holdings weight is 35.80%.
| Rank | XBI | URTH |
|---|---|---|
| #1 | APELLIS PHARMACEUTICALS INC (APLS) - 1.75% | NVIDIA CORP (NVDA) - 5.50% |
| #2 | SUMMIT THERAPEUTICS INC ORDINARY SHARES (SMMT) - 1.62% | APPLE INC (AAPL) - 4.82% |
| #3 | REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.60% | MICROSOFT CORP (MSFT) - 4.00% |
| #4 | TWIST BIOSCIENCE CORP (TWST) - 1.43% | AMAZON.COM INC (AMZN) - 2.61% |
| #5 | TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 1.40% | ALPHABET INC CLASS A (GOOGL) - 2.20% |
| #6 | TG THERAPEUTICS INC (TGTX) - 1.38% | BROADCOM INC (AVGO) - 1.87% |
| #7 | ERASCA INC (ERAS) - 1.34% | ALPHABET INC CLASS C (GOOG) - 1.85% |
| #8 | ARROWHEAD PHARMACEUTICALS INC (ARWR) - 1.31% | META PLATFORMS INC CLASS A (META) - 1.69% |
| #9 | MADRIGAL PHARMACEUTICALS INC (MDGL) - 1.31% | TESLA INC (TSLA) - 1.48% |
| #10 | APOGEE THERAPEUTICS INC (APGE) - 1.30% | JPMORGAN CHASE & CO (JPM) - 1.07% |
| #11 | ALKERMES PLC (ALKS) - 1.29% | ELI LILLY AND CO (LLY) - 1.04% |
| #12 | BEAM THERAPEUTICS INC (BEAM) - 1.26% | BERKSHIRE HATHAWAY INC CLASS B (BRK-B) - 0.82% |
| #13 | n/a (PRAX) - 1.23% | VISA INC CLASS A (V) - 0.71% |
| #14 | SCHOLAR ROCK HOLDING CORP (SRRK) - 1.19% | EXXON MOBIL CORP (XOM) - 0.63% |
| #15 | CRISPR THERAPEUTICS AG (CRSP) - 1.19% | JOHNSON & JOHNSON (JNJ) - 0.60% |
| #16 | EXELIXIS INC (EXEL) - 1.17% | WALMART INC (WMT) - 0.60% |
| #17 | PROTAGONIST THERAPEUTICS INC (PTGX) - 1.17% | MASTERCARD INC CLASS A (MA) - 0.58% |
| #18 | CELCUITY INC (CELC) - 1.16% | ASML HOLDING NV (n/a) - 0.54% |
| #19 | CG ONCOLOGY INC (CGON) - 1.16% | ABBVIE INC (ABBV) - 0.48% |
| #20 | PTC THERAPEUTICS INC (PTCT) - 1.15% | NETFLIX INC (NFLX) - 0.47% |
| #21 | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 1.15% | BANK OF AMERICA CORP (BAC) - 0.47% |
| #22 | BRIDGEBIO PHARMA INC (BBIO) - 1.14% | n/a (PLTR) - 0.46% |
| #23 | NUVALENT INC CLASS A (NUVL) - 1.14% | COSTCO WHOLESALE CORP (COST) - 0.45% |
| #24 | KRYSTAL BIOTECH INC (KRYS) - 1.14% | ADVANCED MICRO DEVICES INC (AMD) - 0.44% |
| #25 | UNITED THERAPEUTICS CORP (UTHR) - 1.12% | MICRON TECHNOLOGY INC (MU) - 0.42% |
| Total Holdings | 157 | 1340 |
XBI vs URTH - Historical Returns
Returns include dividend reinvestment.
1M
XBI
+3.11%
Winner
URTH
+6.92%
3M
Winner
XBI
+6.82%
URTH
+4.59%
6M
Winner
XBI
+24.03%
URTH
+10.80%
1Y
Winner
XBI
+73.24%
URTH
+30.13%
5Y(CAGR)
XBI
+1.17%
Winner
URTH
+11.57%
10Y(CAGR)
XBI
+10.10%
Winner
URTH
+13.23%
Max(CAGR)
XBI
+11.26%
Winner
URTH
+12.23%
XBI vs URTH - Annual Returns (2006 - 2026)
Returns include dividend reinvestment.
| Year | XBI | URTH |
|---|---|---|
| 2026 | +10.85% | +7.58% |
| 2025 | +33.70% | +21.59% |
| 2024 | -0.05% | +19.66% |
| 2023 | +9.54% | +24.14% |
| 2022 | -28.10% | -18.40% |
| 2021 | -20.55% | +23.13% |
| 2020 | +49.01% | +14.90% |
| 2019 | +30.54% | +28.12% |
| 2018 | -17.55% | -9.25% |
| 2017 | +42.81% | +21.83% |
| 2016 | -12.49% | +8.88% |
| 2015 | +12.40% | -0.62% |
| 2014 | +44.27% | +5.44% |
| 2013 | +42.97% | +26.35% |
| 2012 | +32.95% | +14.73% |
| 2011 | +3.91% | N/A |
| 2010 | +15.74% | N/A |
| 2009 | -0.82% | N/A |
| 2008 | -8.58% | N/A |
| 2007 | +30.24% | N/A |
| 2006 | -6.48% | N/A |
XBI vs URTH Drawdown Comparison
The maximum drawdown for XBI was -63.89%, occurring on May 11, 2022. This drawdown has not yet recovered.
The maximum drawdown for URTH was -34.01%, occurring on Mar 23, 2020. Recovery took 134 trading sessions.
The current XBI drawdown is -22.15%.
| Rank | XBI | URTH |
|---|---|---|
| #1 | -63.89% Feb 8, 2021 - May 11, 2022 | -34.01% Feb 12, 2020 - Aug 24, 2020 |
| #2 | -49.25% Jul 17, 2015 - Jan 12, 2018 | -26.04% Jan 3, 2022 - Dec 19, 2023 |
| #3 | -37.67% Aug 14, 2008 - Apr 14, 2011 | -18.89% May 19, 2015 - Dec 13, 2016 |
| #4 | -35.26% Jun 20, 2018 - May 11, 2020 | -18.57% Jan 26, 2018 - Apr 30, 2019 |
| #5 | -29.06% Feb 27, 2014 - Oct 28, 2014 | -16.94% Feb 18, 2025 - Jun 2, 2025 |
| #6 | -26.72% Jul 22, 2011 - Jan 27, 2012 | -11.39% Mar 27, 2012 - Sep 7, 2012 |
| #7 | -22.71% Dec 6, 2007 - Jul 15, 2008 | -10.77% May 21, 2013 - Jul 18, 2013 |
| #8 | -21.93% Feb 27, 2006 - Aug 8, 2007 | -9.32% Jul 3, 2014 - Feb 17, 2015 |
| #9 | -15.10% Sep 21, 2012 - Jan 14, 2013 | -9.06% Feb 25, 2026 - Apr 15, 2026 |
| #10 | -14.51% Jan 29, 2018 - Jun 5, 2018 | -8.23% Jul 16, 2024 - Aug 23, 2024 |
| #11 | -13.70% Jul 20, 2020 - Oct 12, 2020 | -8.10% Sep 2, 2020 - Nov 9, 2020 |
| #12 | -13.36% Oct 2, 2013 - Jan 7, 2014 | -7.00% Sep 14, 2012 - Dec 20, 2012 |
| #13 | -13.21% Mar 19, 2015 - May 29, 2015 | -6.85% Aug 9, 2013 - Sep 18, 2013 |
| #14 | -11.51% Jan 21, 2014 - Feb 20, 2014 | -6.07% Jul 24, 2019 - Oct 17, 2019 |
| #15 | -10.38% May 30, 2013 - Jul 10, 2013 | -6.07% May 3, 2019 - Jun 20, 2019 |
Correlation
Correlation between XBI and URTH is 0.71 which considered as a strong positive correlation - the stocks tend to move together.
0.71
-101
Dividend Comparison (2007 - 2025)
XBI vs URTH dividend yield comparison.
| Year | XBI | URTH |
|---|---|---|
| 2025 | 0.37% | 1.48% |
| 2024 | 0.15% | 1.47% |
| 2023 | 0.02% | 1.70% |
| 2022 | 0.00% | 1.68% |
| 2021 | 0.04% | 1.50% |
| 2020 | 0.20% | 1.52% |
| 2019 | 0.00% | 2.16% |
| 2018 | 0.28% | 2.30% |
| 2017 | 0.24% | 1.88% |
| 2016 | 0.26% | 2.15% |
| 2015 | 0.61% | 2.35% |
| 2014 | 1.07% | 2.31% |
| 2013 | 0.17% | 1.04% |
| 2012 | 0.22% | 2.69% |
| 2009 | 0.28% | 0.00% |
| 2008 | 1.27% | 0.00% |
| 2007 | 0.26% | 0.00% |
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