TYRA vs ZBIO
Comparison between Tyra Biosciences Inc (TYRA, Company) and Zenas Biopharma Inc (ZBIO, Company).
Both TYRA and ZBIO are from the Healthcare sector.
TYRA vs ZBIO - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
TYRA
$1.75B
ZBIO
$1.75B
Max Drawdown
TYRA
83.22%
Winner
ZBIO
74.96%
Sharpe Ratio
Winner
TYRA
2.14
ZBIO
1.56
5Y Beta
Winner
TYRA
1.04
ZBIO
1.26
Industry
TYRA
Biotechnology
ZBIO
Biotechnology
P/E Ratio
Winner
TYRA
-12.36
ZBIO
-3.43
PEG Ratio
TYRA
-0.43
ZBIO
N/A
Debt to Equity
TYRA
0.00%
ZBIO
0.00%
Free Cash Flow Yield
Winner
TYRA
-5.86%
ZBIO
-12.05%
P/S Ratio
TYRA
N/A
ZBIO
119.50
P/B Ratio
Winner
TYRA
4.51
ZBIO
5.26
TYRA vs ZBIO - Historical Returns
Returns include dividend reinvestment.
1M
TYRA
+6.84%
Winner
ZBIO
+58.96%
3M
TYRA
-22.70%
Winner
ZBIO
+26.89%
6M
Winner
TYRA
+14.30%
ZBIO
-21.07%
1Y
Winner
TYRA
+204.68%
ZBIO
+166.44%
5Y(CAGR)
TYRA
+3.47%
ZBIO
N/A
Max(CAGR)
TYRA
+3.47%
Winner
ZBIO
+25.30%
TYRA vs ZBIO - Annual Returns (2021 - 2026)
Returns include dividend reinvestment.
| Year | TYRA | ZBIO |
|---|---|---|
| 2026 | +14.30% | -21.07% |
| 2025 | +82.19% | +303.00% |
| 2024 | -1.00% | -54.88% |
| 2023 | +95.90% | N/A |
| 2022 | -46.06% | N/A |
| 2021 | -45.88% | N/A |
TYRA vs ZBIO Drawdown Comparison
The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.
The maximum drawdown for ZBIO was -74.96%, occurring on Jan 28, 2025. Recovery took 240 trading sessions.
The current TYRA drawdown is -22.70%. The current ZBIO drawdown is -36.92%.
| Rank | TYRA | ZBIO |
|---|---|---|
| #1 | -83.22% Nov 4, 2021 - Jan 27, 2026 | -74.96% Oct 22, 2024 - Oct 8, 2025 |
| #2 | -48.23% Sep 15, 2021 - Nov 3, 2021 | -64.79% Dec 24, 2025 - Jan 6, 2026 |
| #3 | -35.82% Apr 2, 2026 - Jun 10, 2026 | -19.71% Dec 12, 2025 - Dec 22, 2025 |
| #4 | -13.45% Jan 29, 2026 - Feb 23, 2026 | -14.88% Nov 26, 2025 - Dec 12, 2025 |
| #5 | -9.38% Mar 19, 2026 - Mar 31, 2026 | -13.92% Oct 9, 2025 - Oct 27, 2025 |
| #6 | -5.74% Feb 25, 2026 - Mar 4, 2026 | -12.01% Sep 24, 2024 - Oct 15, 2024 |
| #7 | -4.31% Mar 4, 2026 - Mar 11, 2026 | -11.92% Oct 27, 2025 - Nov 6, 2025 |
| #8 | -1.48% Mar 11, 2026 - Mar 16, 2026 | -6.22% Nov 19, 2025 - Nov 24, 2025 |
| #9 | -1.02% Jan 27, 2026 - Jan 29, 2026 | -3.47% Sep 13, 2024 - Sep 20, 2024 |
| #10 | -0.05% Mar 31, 2026 - Apr 2, 2026 | -3.39% Nov 7, 2025 - Nov 11, 2025 |
| #11 | N/A | -2.23% Nov 12, 2025 - Nov 17, 2025 |
| #12 | N/A | -2.16% Sep 20, 2024 - Sep 24, 2024 |
| #13 | N/A | -1.27% Oct 15, 2024 - Oct 17, 2024 |
| #14 | N/A | -0.56% Oct 17, 2024 - Oct 21, 2024 |
Correlation
Correlation between TYRA and ZBIO is 0.53 which considered as a moderate positive correlation - the stocks show some tendency to move together.
0.53
-101
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