TPB vs SEPN

Comparison between Turning Point Brands Inc (TPB, Company) and Septerna Inc (SEPN, Company).

TPB is from the Consumer Defensive sector, while SEPN is from the Healthcare sector.

TPB vs SEPN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TPB(COMPANY)	SEPN(COMPANY)
Market Cap	$1.54B	$1.53B
Max Drawdown	72.85%	81.47%
Sharpe Ratio	0.24	1.78
5Y Beta	0.56	1.24
Industry	Tobacco	Biotechnology
P/E Ratio	23.65	-42.26
Forward P/E	59.17	107.53
PEG Ratio	0.92	N/A
Dividend Yield	0.37%	N/A
5Y Dividends CAGR	8.17%	N/A
5Y EPS CAGR	43.77%	N/A
Debt to Equity	76.24%	0.00%
Free Cash Flow Yield	0.08%	6.99%
P/S Ratio	3.22	21.25
P/B Ratio	4.29	4.11

Market Cap

Winner

TPB

$1.54B

SEPN

$1.53B

Max Drawdown

Winner

TPB

72.85%

SEPN

81.47%

Sharpe Ratio

TPB

0.24

Winner

SEPN

1.78

5Y Beta

Winner

TPB

0.56

SEPN

1.24

Industry

TPB

Tobacco

SEPN

Biotechnology

P/E Ratio

TPB

23.65

Winner

SEPN

-42.26

Forward P/E

Winner

TPB

59.17

SEPN

107.53

PEG Ratio

TPB

0.92

SEPN

N/A

Dividend Yield

TPB

0.37%

SEPN

N/A

5Y Dividends CAGR

TPB

8.17%

SEPN

N/A

5Y EPS CAGR

TPB

43.77%

SEPN

N/A

Debt to Equity

TPB

76.24%

Winner

SEPN

0.00%

Free Cash Flow Yield

TPB

0.08%

Winner

SEPN

6.99%

P/S Ratio

Winner

TPB

3.22

SEPN

21.25

P/B Ratio

TPB

4.29

Winner

SEPN

4.11

TPB vs SEPN - Historical Returns

Returns include dividend reinvestment.

Period	TPB	SEPN
1 month	+5.45%	-3.36%
3 months	+12.82%	+30.54%
6 months	-32.45%	+27.82%
1 year	+1.60%	+173.60%
5 years(CAGR)	+13.07%	N/A
10 years(CAGR)	+22.25%	N/A
Max(CAGR)	+23.15%	+29.86%

Winner

TPB

+5.45%

SEPN

-3.36%

TPB

+12.82%

Winner

SEPN

+30.54%

TPB

-32.45%

Winner

SEPN

+27.82%

TPB

+1.60%

Winner

SEPN

+173.60%

5Y(CAGR)

TPB

+13.07%

SEPN

N/A

10Y(CAGR)

TPB

+22.25%

SEPN

N/A

Max(CAGR)

TPB

+23.15%

Winner

SEPN

+29.86%

TPB vs SEPN - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	TPB	SEPN
2026	-27.69%	+20.37%
2025	+79.40%	+30.59%
2024	+132.30%	+7.01%
2023	+22.88%	N/A
2022	-40.89%	N/A
2021	-11.74%	N/A
2020	+60.31%	N/A
2019	+4.72%	N/A
2018	+31.62%	N/A
2017	+69.97%	N/A
2016	+21.05%	N/A

TPB vs SEPN Drawdown Comparison

The maximum drawdown for TPB was -72.75%, occurring on Mar 18, 2020. Recovery took 392 trading sessions.

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The current TPB drawdown is -44.25%. The current SEPN drawdown is -10.99%.

Rank	TPB	SEPN
#1	-72.75% Jul 18, 2019 - Feb 5, 2021	-81.47% Dec 23, 2024 - Nov 24, 2025
#2	-66.44% Feb 12, 2021 - Nov 14, 2024	-25.18% Feb 24, 2026 - May 28, 2026
#3	-50.58% Feb 25, 2026 - Apr 21, 2026	-21.10% Dec 19, 2025 - Feb 17, 2026
#4	-39.36% May 17, 2016 - Aug 15, 2016	-16.77% Dec 4, 2024 - Dec 23, 2024
#5	-37.90% Oct 8, 2018 - Mar 5, 2019	-16.60% Jul 9, 2026 - Jul 16, 2026
#6	-24.78% Sep 8, 2016 - Apr 10, 2017	-16.19% Nov 7, 2024 - Dec 4, 2024
#7	-22.38% Mar 3, 2025 - May 7, 2025	-13.97% Nov 26, 2025 - Dec 19, 2025
#8	-17.32% Sep 23, 2025 - Nov 7, 2025	-10.63% Feb 17, 2026 - Feb 24, 2026
#9	-17.29% Mar 18, 2019 - May 1, 2019	-10.36% Jun 26, 2026 - Jul 9, 2026
#10	-16.98% Oct 17, 2017 - Dec 27, 2017	-6.45% Oct 25, 2024 - Oct 31, 2024
#11	-15.63% Aug 2, 2018 - Sep 5, 2018	-5.55% Jun 23, 2026 - Jun 26, 2026
#12	-15.19% Apr 24, 2017 - Aug 30, 2017	-4.76% Oct 31, 2024 - Nov 4, 2024
#13	-14.12% Dec 6, 2024 - Feb 6, 2025	-3.65% Jun 18, 2026 - Jun 23, 2026
#14	-14.05% Aug 15, 2016 - Aug 24, 2016	-3.57% May 28, 2026 - Jun 4, 2026
#15	-13.77% Jan 12, 2018 - May 10, 2018	-3.45% Nov 4, 2024 - Nov 6, 2024