SYRE vs THG

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Hanover Insurance Group Inc (THG, Company).

SYRE is from the Healthcare sector, while THG is from the Financial Services sector.

5-Year PerformanceTHG has outperformed SYRE, delivering a return of +11.4% compared to -11.3%

SYRE vs THG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	THG(COMPANY)
Market Cap	$6.96B	$6.97B
Max Drawdown	99.11%	90.12%
Sharpe Ratio	2.89	0.85
5Y Beta	1.76	0.34
Industry	Biotechnology	Insurance - Property & Casualty
P/E Ratio	-35.79	10.85
Forward P/E	N/A	11.34
PEG Ratio	N/A	0.07
Dividend Yield	N/A	1.86%
5Y Dividends CAGR	N/A	11.08%
5Y EPS CAGR	-2.15%	13.85%
Debt to Equity	0.00%	23.63%
Free Cash Flow Yield	-2.67%	17.92%

Market Cap

SYRE

$6.96B

Winner

THG

$6.97B

Max Drawdown

SYRE

99.11%

Winner

THG

90.12%

Sharpe Ratio

Winner

SYRE

2.89

THG

0.85

5Y Beta

SYRE

1.76

Winner

THG

0.34

Industry

SYRE

Biotechnology

THG

Insurance - Property & Casualty

P/E Ratio

Winner

SYRE

-35.79

THG

10.85

Forward P/E

SYRE

N/A

THG

11.34

PEG Ratio

SYRE

N/A

THG

0.07

Dividend Yield

SYRE

N/A

THG

1.86%

5Y Dividends CAGR

SYRE

N/A

THG

11.08%

5Y EPS CAGR

SYRE

-2.15%

Winner

THG

13.85%

Debt to Equity

Winner

SYRE

0.00%

THG

23.63%

Free Cash Flow Yield

SYRE

-2.67%

Winner

THG

17.92%

SYRE vs THG - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	THG
1 month	+26.06%	+0.68%
3 months	+105.16%	+16.71%
6 months	+163.94%	+7.94%
1 year	+485.81%	+21.02%
5 years(CAGR)	-11.31%	+11.36%
10 years(CAGR)	-2.30%	+12.32%
Max(CAGR)	-9.49%	+7.09%

Winner

SYRE

+26.06%

THG

+0.68%

Winner

SYRE

+105.16%

THG

+16.71%

Winner

SYRE

+163.94%

THG

+7.94%

Winner

SYRE

+485.81%

THG

+21.02%

5Y(CAGR)

SYRE

-11.31%

Winner

THG

+11.36%

10Y(CAGR)

SYRE

-2.30%

Winner

THG

+12.32%

Max(CAGR)

SYRE

-9.49%

Winner

THG

+7.09%

SYRE vs THG - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYRE	THG
2026	+188.88%	+11.68%
2025	+37.36%	+22.40%
2024	+8.79%	+29.01%
2023	+104.27%	-8.17%
2022	-90.57%	+5.29%
2021	-44.51%	+16.88%
2020	+1.55%	-12.07%
2019	-4.98%	+28.32%
2018	+39.22%	+11.54%
2017	+18.38%	+21.12%
2016	-55.48%	+16.52%
2015	N/A	+17.70%
2014	N/A	+24.30%
2013	N/A	+56.55%
2012	N/A	+13.94%
2011	N/A	-23.17%
2010	N/A	+7.08%
2009	N/A	+5.78%
2008	N/A	-3.40%
2007	N/A	-5.87%
2006	N/A	+14.26%
2005	N/A	+29.10%
2004	N/A	+6.45%
2003	N/A	+204.96%
2002	N/A	-76.57%
2001	N/A	-33.33%
2000	N/A	+36.05%
1999	N/A	+1.24%

SYRE vs THG Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for THG was -89.84%, occurring on Oct 9, 2002. Recovery took 3234 trading sessions.

The current SYRE drawdown is -70.53%. The current THG drawdown is -0.87%.

Rank	SYRE	THG
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-89.84% Dec 29, 2000 - Nov 8, 2013
#2	N/A	-40.84% Nov 8, 1999 - May 24, 2000
#3	N/A	-40.05% Feb 4, 2020 - Apr 27, 2021
#4	N/A	-30.38% Apr 20, 2022 - Aug 30, 2024
#5	N/A	-18.50% Aug 21, 2018 - May 10, 2019
#6	N/A	-17.77% Apr 1, 2016 - Dec 8, 2016
#7	N/A	-14.04% Aug 27, 2021 - Feb 3, 2022
#8	N/A	-13.98% Apr 2, 2025 - May 30, 2025
#9	N/A	-13.34% Jan 10, 2014 - Mar 31, 2014
#10	N/A	-12.87% May 24, 2000 - Jul 27, 2000
#11	N/A	-11.94% Oct 3, 2000 - Dec 7, 2000
#12	N/A	-11.73% Mar 15, 2017 - Jul 20, 2017
#13	N/A	-11.07% Aug 16, 2017 - Oct 10, 2017
#14	N/A	-10.68% Nov 11, 2015 - Mar 11, 2016
#15	N/A	-10.32% Nov 29, 2024 - Feb 6, 2025

Correlation

Correlation between SYRE and THG is -0.56 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.56

-101