SYRE vs VNOM

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Viper Energy Inc - Class A (VNOM, Company).

SYRE is from the Healthcare sector, while VNOM is from the Energy sector.

5-Year PerformanceVNOM has outperformed SYRE, delivering a return of +26.4% compared to -11.3%

SYRE vs VNOM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	VNOM(COMPANY)
Market Cap	$6.96B	$6.95B
Max Drawdown	99.11%	88.17%
Sharpe Ratio	2.89	0.33
5Y Beta	1.76	0.75
Industry	Biotechnology	Oil & Gas Midstream
P/E Ratio	-35.79	19.21
Forward P/E	N/A	21.32
PEG Ratio	N/A	0.65
Dividend Yield	N/A	5.32%
5Y Dividends CAGR	N/A	40.82%
5Y EPS CAGR	-2.15%	N/A
Debt to Equity	0.00%	56.73%
Free Cash Flow Yield	-2.67%	N/A
P/S Ratio	N/A	13.46
P/B Ratio	N/A	1.92

Market Cap

Winner

SYRE

$6.96B

VNOM

$6.95B

Max Drawdown

SYRE

99.11%

Winner

VNOM

88.17%

Sharpe Ratio

Winner

SYRE

2.89

VNOM

0.33

5Y Beta

SYRE

1.76

Winner

VNOM

0.75

Industry

SYRE

Biotechnology

VNOM

Oil & Gas Midstream

P/E Ratio

Winner

SYRE

-35.79

VNOM

19.21

Forward P/E

SYRE

N/A

VNOM

21.32

PEG Ratio

SYRE

N/A

VNOM

0.65

Dividend Yield

SYRE

N/A

VNOM

5.32%

5Y Dividends CAGR

SYRE

N/A

VNOM

40.82%

5Y EPS CAGR

SYRE

-2.15%

VNOM

N/A

Debt to Equity

Winner

SYRE

0.00%

VNOM

56.73%

Free Cash Flow Yield

SYRE

-2.67%

VNOM

N/A

P/S Ratio

SYRE

N/A

VNOM

13.46

P/B Ratio

SYRE

N/A

VNOM

1.92

SYRE vs VNOM - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	VNOM
1 month	+26.06%	-12.03%
3 months	+105.16%	-7.03%
6 months	+163.94%	+16.00%
1 year	+485.81%	+11.81%
5 years(CAGR)	-11.31%	+26.37%
10 years(CAGR)	-2.30%	+15.07%
Max(CAGR)	-9.49%	+8.54%

Winner

SYRE

+26.06%

VNOM

-12.03%

Winner

SYRE

+105.16%

VNOM

-7.03%

Winner

SYRE

+163.94%

VNOM

+16.00%

Winner

SYRE

+485.81%

VNOM

+11.81%

5Y(CAGR)

SYRE

-11.31%

Winner

VNOM

+26.37%

10Y(CAGR)

SYRE

-2.30%

Winner

VNOM

+15.07%

Max(CAGR)

SYRE

-9.49%

Winner

VNOM

+8.54%

SYRE vs VNOM - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SYRE	VNOM
2026	+188.88%	+14.36%
2025	+37.36%	-17.87%
2024	+8.79%	+67.82%
2023	+104.27%	+14.77%
2022	-90.57%	+53.66%
2021	-44.51%	+85.15%
2020	+1.55%	-52.92%
2019	-4.98%	-2.14%
2018	+39.22%	+18.28%
2017	+18.38%	+53.47%
2016	-55.48%	+22.08%
2015	N/A	-25.50%
2014	N/A	-43.22%

SYRE vs VNOM Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for VNOM was -86.96%, occurring on Mar 23, 2020. Recovery took 925 trading sessions.

The current SYRE drawdown is -70.53%. The current VNOM drawdown is -16.85%.

Rank	SYRE	VNOM
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-86.96% Oct 3, 2018 - Jun 7, 2022
#2	N/A	-60.00% Jun 23, 2014 - Apr 13, 2018
#3	N/A	-34.44% Nov 22, 2024 - Apr 10, 2025
#4	N/A	-32.44% Jun 7, 2022 - Nov 7, 2022
#5	N/A	-26.71% Nov 7, 2022 - Feb 14, 2024
#6	N/A	-20.06% May 21, 2018 - Jul 9, 2018
#7	N/A	-11.29% Aug 26, 2024 - Oct 3, 2024
#8	N/A	-10.66% Jul 10, 2018 - Aug 1, 2018
#9	N/A	-10.53% Apr 11, 2024 - Jul 15, 2024
#10	N/A	-8.71% Mar 5, 2024 - Mar 28, 2024
#11	N/A	-8.53% Jul 19, 2024 - Aug 6, 2024
#12	N/A	-7.17% Nov 6, 2024 - Nov 22, 2024
#13	N/A	-5.58% May 9, 2018 - May 18, 2018
#14	N/A	-5.20% Aug 27, 2018 - Sep 18, 2018
#15	N/A	-3.83% Aug 6, 2018 - Aug 9, 2018

Correlation

Correlation between SYRE and VNOM is -0.63 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.63

-101