SYRE vs PCTY

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Paylocity Holding Corp (PCTY, Company).

SYRE is from the Healthcare sector, while PCTY is from the Technology sector.

5-Year PerformanceSYRE has outperformed PCTY, delivering a return of -7.9% compared to -8.0%

SYRE vs PCTY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	PCTY(COMPANY)
Market Cap	$7.72B	$7.75B
Max Drawdown	99.11%	68.90%
Sharpe Ratio	2.88	-0.71
5Y Beta	1.76	0.60
Industry	Biotechnology	Software - Application
P/E Ratio	-39.65	30.35
Forward P/E	N/A	15.70
PEG Ratio	N/A	1.81
5Y EPS CAGR	-2.15%	32.33%
Debt to Equity	0.00%	6.88%
Free Cash Flow Yield	-2.41%	6.28%
P/S Ratio	650.22	4.49
P/B Ratio	16.86	6.29

Market Cap

SYRE

$7.72B

Winner

PCTY

$7.75B

Max Drawdown

SYRE

99.11%

Winner

PCTY

68.90%

Sharpe Ratio

Winner

SYRE

2.88

PCTY

-0.71

5Y Beta

SYRE

1.76

Winner

PCTY

0.60

Industry

SYRE

Biotechnology

PCTY

Software - Application

P/E Ratio

Winner

SYRE

-39.65

PCTY

30.35

Forward P/E

SYRE

N/A

PCTY

15.70

PEG Ratio

SYRE

N/A

PCTY

1.81

5Y EPS CAGR

SYRE

-2.15%

Winner

PCTY

32.33%

Debt to Equity

Winner

SYRE

0.00%

PCTY

6.88%

Free Cash Flow Yield

SYRE

-2.41%

Winner

PCTY

6.28%

P/S Ratio

SYRE

650.22

Winner

PCTY

4.49

P/B Ratio

SYRE

16.86

Winner

PCTY

6.29

SYRE vs PCTY - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	PCTY
1 month	+14.33%	+30.79%
3 months	+36.33%	+29.60%
6 months	+217.39%	+1.28%
1 year	+487.04%	-26.66%
5 years(CAGR)	-7.91%	-8.00%
10 years(CAGR)	-1.66%	+11.84%
Max(CAGR)	-8.16%	+15.09%

SYRE

+14.33%

Winner

PCTY

+30.79%

Winner

SYRE

+36.33%

PCTY

+29.60%

Winner

SYRE

+217.39%

PCTY

+1.28%

Winner

SYRE

+487.04%

PCTY

-26.66%

5Y(CAGR)

Winner

SYRE

-7.91%

PCTY

-8.00%

10Y(CAGR)

SYRE

-1.66%

Winner

PCTY

+11.84%

Max(CAGR)

SYRE

-8.16%

Winner

PCTY

+15.09%

SYRE vs PCTY - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SYRE	PCTY
2026	+231.92%	-6.17%
2025	+37.36%	-21.82%
2024	+8.79%	+22.52%
2023	+104.27%	-14.38%
2022	-90.57%	-16.21%
2021	-44.51%	+18.66%
2020	+1.55%	+62.42%
2019	-4.98%	+102.89%
2018	+39.22%	+26.15%
2017	+18.38%	+56.73%
2016	-55.48%	-22.17%
2015	N/A	+57.97%
2014	N/A	+8.61%

SYRE vs PCTY Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for PCTY was -68.90%, occurring on Apr 10, 2026. This drawdown has not yet recovered.

The current SYRE drawdown is -66.14%. The current PCTY drawdown is -55.29%.

Rank	SYRE	PCTY
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-68.90% Nov 1, 2021 - Apr 10, 2026
#2	N/A	-50.57% Feb 4, 2020 - Jul 1, 2020
#3	N/A	-45.55% Nov 19, 2015 - Aug 4, 2016
#4	N/A	-40.41% Mar 21, 2014 - Nov 7, 2014
#5	N/A	-36.70% Aug 8, 2016 - Jun 1, 2017
#6	N/A	-35.97% Sep 14, 2018 - Feb 19, 2019
#7	N/A	-26.96% Dec 23, 2020 - Aug 5, 2021
#8	N/A	-23.64% Nov 21, 2014 - Feb 19, 2015
#9	N/A	-22.59% Aug 5, 2015 - Nov 6, 2015
#10	N/A	-19.66% Oct 31, 2017 - Mar 12, 2018
#11	N/A	-17.47% Mar 20, 2015 - May 8, 2015
#12	N/A	-16.92% Jul 2, 2020 - Sep 28, 2020
#13	N/A	-15.07% Aug 27, 2019 - Nov 15, 2019
#14	N/A	-13.76% Jul 26, 2019 - Aug 9, 2019
#15	N/A	-13.09% May 16, 2019 - Jul 11, 2019

Correlation

Correlation between SYRE and PCTY is -0.45 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.45

-101