SYRE vs MRCY

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Mercury Systems Inc (MRCY, Company).

SYRE is from the Healthcare sector, while MRCY is from the Industrials sector.

5-Year PerformanceMRCY has outperformed SYRE, delivering a return of +8.3% compared to -16.9%

SYRE vs MRCY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	MRCY(COMPANY)
Market Cap	$5.67B	$5.64B
Max Drawdown	99.11%	95.95%
Sharpe Ratio	2.60	1.50
5Y Beta	1.75	1.06
Industry	Biotechnology	Aerospace & Defense
P/E Ratio	-29.14	-402.66
Forward P/E	N/A	61.35
5Y EPS CAGR	-2.15%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-3.27%	1.30%

Market Cap

Winner

SYRE

$5.67B

MRCY

$5.64B

Max Drawdown

SYRE

99.11%

Winner

MRCY

95.95%

Sharpe Ratio

Winner

SYRE

2.60

MRCY

1.50

5Y Beta

SYRE

1.75

Winner

MRCY

1.06

Industry

SYRE

Biotechnology

MRCY

Aerospace & Defense

P/E Ratio

SYRE

-29.14

Winner

MRCY

-402.66

Forward P/E

SYRE

N/A

MRCY

61.35

5Y EPS CAGR

SYRE

-2.15%

MRCY

N/A

Debt to Equity

SYRE

0.00%

MRCY

0.00%

Free Cash Flow Yield

SYRE

-3.27%

Winner

MRCY

1.30%

SYRE vs MRCY - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	MRCY
1 month	-2.00%	+12.71%
3 months	+66.44%	+8.19%
6 months	+206.43%	+43.39%
1 year	+367.01%	+97.32%
5 years(CAGR)	-16.95%	+8.34%
10 years(CAGR)	-9.09%	+16.47%
Max(CAGR)	-11.38%	+5.33%

SYRE

-2.00%

Winner

MRCY

+12.71%

Winner

SYRE

+66.44%

MRCY

+8.19%

Winner

SYRE

+206.43%

MRCY

+43.39%

Winner

SYRE

+367.01%

MRCY

+97.32%

5Y(CAGR)

SYRE

-16.95%

Winner

MRCY

+8.34%

10Y(CAGR)

SYRE

-9.09%

Winner

MRCY

+16.47%

Max(CAGR)

SYRE

-11.38%

Winner

MRCY

+5.33%

SYRE vs MRCY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYRE	MRCY
2026	+135.19%	+24.70%
2025	+37.36%	+72.52%
2024	+8.79%	+16.50%
2023	+104.27%	-17.93%
2022	-90.57%	-21.22%
2021	-44.51%	-34.79%
2020	+1.55%	+24.05%
2019	-4.98%	+51.32%
2018	+39.22%	-5.80%
2017	+18.38%	+71.17%
2016	-55.48%	+67.61%
2015	N/A	+36.10%
2014	N/A	+26.55%
2013	N/A	+17.62%
2012	N/A	-32.85%
2011	N/A	-29.35%
2010	N/A	+57.63%
2009	N/A	+65.56%
2008	N/A	-60.01%
2007	N/A	+19.51%
2006	N/A	-33.99%
2005	N/A	-30.33%
2004	N/A	+16.67%
2003	N/A	-20.62%
2002	N/A	-22.87%
2001	N/A	-4.61%
2000	N/A	+42.89%
1999	N/A	+46.60%

SYRE vs MRCY Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for MRCY was -95.95%, occurring on Dec 1, 2008. Recovery took 4748 trading sessions.

The current SYRE drawdown is -76.01%. The current MRCY drawdown is -7.97%.

Rank	SYRE	MRCY
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-95.95% Mar 23, 2000 - Feb 7, 2019
#2	N/A	-71.73% Apr 29, 2020 - Jan 9, 2026
#3	N/A	-35.66% Aug 21, 2019 - Apr 29, 2020
#4	N/A	-32.19% Jan 16, 2026 - Mar 30, 2026
#5	N/A	-24.04% Feb 9, 2000 - Feb 29, 2000
#6	N/A	-16.74% Nov 29, 1999 - Dec 27, 1999
#7	N/A	-15.71% Dec 31, 1999 - Jan 20, 2000
#8	N/A	-15.65% Jan 20, 2000 - Jan 25, 2000
#9	N/A	-14.68% May 6, 2019 - Jul 31, 2019
#10	N/A	-12.28% Nov 8, 1999 - Nov 22, 1999
#11	N/A	-10.85% Feb 20, 2019 - Apr 10, 2019
#12	N/A	-9.45% Mar 10, 2000 - Mar 17, 2000
#13	N/A	-9.27% Mar 1, 2000 - Mar 9, 2000
#14	N/A	-6.98% Jan 26, 2000 - Feb 7, 2000
#15	N/A	-5.29% Jul 31, 2019 - Aug 8, 2019