SYRE vs KLIC

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Kulicke & Soffa Industries Inc (KLIC, Company).

SYRE is from the Healthcare sector, while KLIC is from the Technology sector.

5-Year PerformanceKLIC has outperformed SYRE, delivering a return of +17.2% compared to -13.2%

SYRE vs KLIC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	KLIC(COMPANY)
Market Cap	$7.01B	$7B
Max Drawdown	99.11%	97.35%
Sharpe Ratio	2.86	2.93
5Y Beta	1.75	1.68
Industry	Biotechnology	Semiconductor Equipment & Materials
P/E Ratio	-36.02	127.11
Forward P/E	N/A	30.21
PEG Ratio	N/A	0.72
Dividend Yield	N/A	0.64%
5Y Dividends CAGR	N/A	14.54%
5Y EPS CAGR	-2.15%	-9.89%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.65%	0.06%

Market Cap

Winner

SYRE

$7.01B

KLIC

$7B

Max Drawdown

SYRE

99.11%

Winner

KLIC

97.35%

Sharpe Ratio

SYRE

2.86

Winner

KLIC

2.93

5Y Beta

SYRE

1.75

Winner

KLIC

1.68

Industry

SYRE

Biotechnology

KLIC

Semiconductor Equipment & Materials

P/E Ratio

Winner

SYRE

-36.02

KLIC

127.11

Forward P/E

SYRE

N/A

KLIC

30.21

PEG Ratio

SYRE

N/A

KLIC

0.72

Dividend Yield

SYRE

N/A

KLIC

0.64%

5Y Dividends CAGR

SYRE

N/A

KLIC

14.54%

5Y EPS CAGR

Winner

SYRE

-2.15%

KLIC

-9.89%

Debt to Equity

SYRE

0.00%

KLIC

0.00%

Free Cash Flow Yield

SYRE

-2.65%

Winner

KLIC

0.06%

SYRE vs KLIC - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	KLIC
1 month	+25.26%	+12.16%
3 months	+82.07%	+89.66%
6 months	+183.29%	+152.14%
1 year	+458.90%	+234.53%
5 years(CAGR)	-13.19%	+17.23%
10 years(CAGR)	-3.31%	+27.58%
Max(CAGR)	-9.63%	+8.76%

Winner

SYRE

+25.26%

KLIC

+12.16%

SYRE

+82.07%

Winner

KLIC

+89.66%

Winner

SYRE

+183.29%

KLIC

+152.14%

Winner

SYRE

+458.90%

KLIC

+234.53%

5Y(CAGR)

SYRE

-13.19%

Winner

KLIC

+17.23%

10Y(CAGR)

SYRE

-3.31%

Winner

KLIC

+27.58%

Max(CAGR)

SYRE

-9.63%

Winner

KLIC

+8.76%

SYRE vs KLIC - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYRE	KLIC
2026	+183.29%	+152.14%
2025	+37.36%	-1.08%
2024	+8.79%	-10.00%
2023	+104.27%	+29.20%
2022	-90.57%	-31.27%
2021	-44.51%	+89.58%
2020	+1.55%	+17.82%
2019	-4.98%	+36.87%
2018	+39.22%	-15.80%
2017	+18.38%	+49.69%
2016	-55.48%	+41.03%
2015	N/A	-18.90%
2014	N/A	+10.80%
2013	N/A	+4.89%
2012	N/A	+26.21%
2011	N/A	+28.47%
2010	N/A	+31.15%
2009	N/A	+191.35%
2008	N/A	-74.32%
2007	N/A	-18.62%
2006	N/A	-6.87%
2005	N/A	+6.76%
2004	N/A	-38.65%
2003	N/A	+136.51%
2002	N/A	-68.12%
2001	N/A	+46.71%
2000	N/A	-45.86%
1999	N/A	+43.06%

SYRE vs KLIC Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for KLIC was -97.35%, occurring on Nov 20, 2008. Recovery took 5263 trading sessions.

The current SYRE drawdown is -71.10%. The current KLIC drawdown is -9.33%.

Rank	SYRE	KLIC
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-97.35% Mar 6, 2000 - Feb 4, 2021
#2	N/A	-60.44% Sep 7, 2021 - Feb 6, 2026
#3	N/A	-26.01% Apr 26, 2021 - Jun 25, 2021
#4	N/A	-19.62% Jun 28, 2021 - Aug 6, 2021
#5	N/A	-18.64% Nov 17, 1999 - Dec 21, 1999
#6	N/A	-18.14% Feb 17, 2021 - Apr 5, 2021
#7	N/A	-17.90% Feb 11, 2026 - Apr 9, 2026
#8	N/A	-13.98% Jan 18, 2000 - Feb 4, 2000
#9	N/A	-9.59% May 26, 2026 - Jun 11, 2026
#10	N/A	-9.55% Aug 10, 2021 - Sep 1, 2021
#11	N/A	-9.33% Jul 1, 2026 - Jul 2, 2026
#12	N/A	-8.65% Dec 21, 1999 - Jan 7, 2000
#13	N/A	-7.40% Apr 6, 2021 - Apr 23, 2021
#14	N/A	-7.03% Nov 9, 1999 - Nov 17, 1999
#15	N/A	-6.77% Feb 10, 2000 - Feb 22, 2000

Correlation

Correlation between SYRE and KLIC is -0.46 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.46

-101