SYRE vs FRHC

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Freedom Holding Corp (FRHC, Company).

SYRE is from the Healthcare sector, while FRHC is from the Financial Services sector.

5-Year PerformanceFRHC has outperformed SYRE, delivering a return of +18.2% compared to -8.5%

SYRE vs FRHC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	FRHC(COMPANY)
Market Cap	$9.19B	$9.16B
Max Drawdown	99.11%	45.93%
Sharpe Ratio	2.99	-0.41
5Y Beta	1.79	1.17
Industry	Biotechnology	Financial Conglomerates
P/E Ratio	-45.95	59.66
Forward P/E	N/A	12.29
PEG Ratio	N/A	0.62
5Y EPS CAGR	-2.73%	30.78%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.27%	-0.15%
P/S Ratio	650.22	5.82
P/B Ratio	16.58	6.60

Market Cap

Winner

SYRE

$9.19B

FRHC

$9.16B

Max Drawdown

SYRE

99.11%

Winner

FRHC

45.93%

Sharpe Ratio

Winner

SYRE

2.99

FRHC

-0.41

5Y Beta

SYRE

1.79

Winner

FRHC

1.17

Industry

SYRE

Biotechnology

FRHC

Financial Conglomerates

P/E Ratio

Winner

SYRE

-45.95

FRHC

59.66

Forward P/E

SYRE

N/A

FRHC

12.29

PEG Ratio

SYRE

N/A

FRHC

0.62

5Y EPS CAGR

SYRE

-2.73%

Winner

FRHC

30.78%

Debt to Equity

SYRE

0.00%

FRHC

0.00%

Free Cash Flow Yield

SYRE

-2.27%

Winner

FRHC

-0.15%

P/S Ratio

SYRE

650.22

Winner

FRHC

5.82

P/B Ratio

SYRE

16.58

Winner

FRHC

6.60

SYRE vs FRHC - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	FRHC
1 month	+11.33%	-2.66%
3 months	+43.52%	+7.16%
6 months	+198.72%	+21.36%
1 year	+588.39%	-19.88%
5 years(CAGR)	-8.54%	+18.20%
10 years(CAGR)	-0.91%	+63.38%
Max(CAGR)	-7.85%	+63.38%

Winner

SYRE

+11.33%

FRHC

-2.66%

Winner

SYRE

+43.52%

FRHC

+7.16%

Winner

SYRE

+198.72%

FRHC

+21.36%

Winner

SYRE

+588.39%

FRHC

-19.88%

5Y(CAGR)

SYRE

-8.54%

Winner

FRHC

+18.20%

10Y(CAGR)

SYRE

-0.91%

Winner

FRHC

+63.38%

Max(CAGR)

SYRE

-7.85%

Winner

FRHC

+63.38%

SYRE vs FRHC - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	SYRE	FRHC
2026	+243.07%	+19.92%
2025	+37.36%	-8.68%
2024	+8.79%	+63.69%
2023	+104.27%	+39.78%
2022	-90.57%	-16.73%
2021	-44.51%	+38.74%
2020	+1.55%	+249.29%
2019	-4.98%	+75.60%
2018	+39.22%	+29.06%
2017	+18.38%	+227.84%
2016	-55.48%	N/A

SYRE vs FRHC Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for FRHC was -45.93%, occurring on Jun 16, 2022. Recovery took 320 trading sessions.

The current SYRE drawdown is -65.00%. The current FRHC drawdown is -21.65%.

Rank	SYRE	FRHC
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-45.93% Nov 8, 2021 - Feb 16, 2023
#2	N/A	-41.08% Aug 6, 2025 - Feb 19, 2026
#3	N/A	-38.69% Oct 17, 2017 - Nov 15, 2017
#4	N/A	-35.24% Aug 30, 2023 - Oct 17, 2024
#5	N/A	-29.13% Feb 13, 2025 - May 13, 2025
#6	N/A	-27.84% Feb 19, 2020 - May 26, 2020
#7	N/A	-25.25% Feb 7, 2018 - Sep 27, 2018
#8	N/A	-25.20% Feb 16, 2021 - Jun 15, 2021
#9	N/A	-24.46% May 20, 2025 - Jul 31, 2025
#10	N/A	-22.51% Dec 3, 2018 - Jan 18, 2019
#11	N/A	-16.57% Jun 13, 2023 - Aug 18, 2023
#12	N/A	-16.49% Jan 18, 2019 - May 9, 2019
#13	N/A	-15.73% Jan 12, 2018 - Jan 26, 2018
#14	N/A	-13.44% Feb 16, 2023 - May 5, 2023
#15	N/A	-13.28% Nov 30, 2017 - Dec 28, 2017